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Biomedical subjects

C Kelty

Publications and source records attributed to C Kelty.

7 recordsLinked to original sources
PubMed2001

The history of photodetection and photodynamic therapy.

Light has been employed in the treatment of disease since antiquity. Many ancient civilizations utilized phototherapy, but it was not until early last century that this form of therapy reappeared. Following the scientific discoveries by early pioneers such as Finsen, Raab and Von Tappeiner, the combination of light and drug administration led to the emergence of photochemotherapy as a therapeutic tool. The isolation of porphyrins and the subsequent discovery of their tumor-localizing properties and phototoxic effects on tumor tissue led to the development of modern photodetection (PD) and photodynamic therapy (PDT). This review traces the origins and development of PD and PDT from antiquity to the present day.

Aminolevulinic Acid↗
PubMed2000

Traumatic abscess of pectoralis major.

Pectoralis major rupture is a well-recognised but uncommon injury that rarely leads to complications. We present an unusual case where the resultant haematoma following a partial rupture became infected and caused problems with diagnosis. We are only aware of one previous report of this.

Abscess↗
PubMed1999

Out-of-hours work in cardiothoracic surgery: implications of the New Deal and Calman for training.

With the introduction of the New Deal and the Calman Report, the duration of higher specialist training will be halved. We have examined the effect of reduced on-call rotas on exposure to relatively uncommon out-of-hours emergencies in cardiothoracic surgery. Operations for post-infarction ventricular septal defect, aortic dissection or transection, oesophageal perforation and pulmonary embolus performed out-of-hours between 1990 and 1995 were identified from hospital records. Over 6 years, the period of higher specialist training in cardiothoracic surgery, a trainee would see seven aortic emergencies on a 1:2 rota, four on a 1:4 rota and two on a 1:6 rota. These figures provide a powerful argument in support of the English Clause which allows trainees to be available for 83 hours a week, equivalent to a 1:4 rota, rather than 56 hours a week, equivalent to a 1:6 rota under the New Deal. This may need supplementation by a mechanism whereby trainees are 'on call for training'.

Education, Medical, Graduate↗