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Biomedical subjects

C Kirkland

Publications and source records attributed to C Kirkland.

6 recordsLinked to original sources
PubMed1990

Intersalt in Newfoundland and Labrador.

In Intersalt, positive relations between 24-hour urinary sodium and potassium excretion and blood pressure were observed in over 10,000 men and women in 52 centers around the world. Body mass index (BMI), alcohol intake and smoking showed different associations with blood pressure in various population groups. We investigated these variables in the 2 Canadian centers and could not confirm the sodium-potassium relationship. In a multiple stepwise regression analysis, BMI and alcohol had the strongest relation with blood pressure in men. Among the female participants, BMI and sodium were the most influential factors on systolic blood pressure. For diastolic blood pressure, BMI and smoking showed the strongest significance. Neither in men nor in women could the influence of high sodium and low potassium excretion on blood pressure be discerned.

Adult↗
PubMed1987

A subretinal neovascular membrane as a complication of endogenous Candida endophthalmitis.

A 21-year-old woman developed endophthalmitis and a macular chorioretinal lesion secondarily to a Candida infection. She had been receiving intensive systemic antibiotic and steroid therapy for pelvic inflammatory disease. Blood cultures confirmed a Candida albicans septicemia, and amphotericin B was administered intravenously. As the eye inflammation resolved, healing of the chorioretinal lesion was complicated by the development of a subretinal neovascular membrane. The authors hypothesize that the formation of the membrane was related to an inflammatory alteration of the pigment epithelium--Bruch's membrane--choriocapillaris complex. To the authors' knowledge, this is the first such report following a Candida infection of the eye.

Adult↗
PubMed1984

Vision and eye problems in seven year olds: a report from the Dunedin Multidisciplinary Health and Development Research Unit.

An eye examination, including tests of distance visual acuity, near visual acuity, cover tests, and an examination of pupils, eyes, adnexia, and eye movements, was carried out on 988 Dunedin children within approximately one month of their seventh birthday. Information concerning glasses and patching of one eye was obtained by questionnaire. Eye defects were noted in 9.4% of the children with several having more than one problem. Eye defects noted included 5.1% with unaided distance visual acuity of 6/12 or worse in one or both eyes, 4.4% with near visual acuity of the equivalent of N8 or worse in one or both eyes, 3.9% had manifest strabismus, 2.9% had had occlusion of one eye for amblyopia, and 1.2% had other important eye defects. Glasses had been prescribed for 3.6%.

Amblyopia↗
PubMed1983

A preliminary evaluation of the use of an automatic impedance tympanometer in the diagnosis of otitis media with effusion in children: a report from the Dunedin Multidisciplinary Health and Development Research Unit.

Microscopic examination by two trained examiners, conventional impedance tympanometry by a trained audiometrist, automatic impedance tympanometry by a person with minimal training and puretone audiometry by trained audiometrists were compared in 468 ears, studied blind. There was complete examiner agreement in microscopic examination in 465 (99.3%) ears, minor disagreement in three (0.7%) ears. There was a more complex relationship between examination methods, with microscopic evidence of effusion being present in 88.2% of ears showing B tympanograms to conventional tympanometry and in 66.7% of ears to automatic tympanometry. Automatic tympanometry provides a reasonably accurate method of detecting middle ear effusion, but tends to overdiagnose this condition compared to alternate methods.

Acoustic Impedance Tests↗