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Biomedical subjects

C Kirtley

Publications and source records attributed to C Kirtley.

6 recordsLinked to original sources

EMG fatigue patterns accompanying isometric fatiguing knee-extensions are different in mono- and bi-articular muscles.

OBJECTIVES AND METHODS: Isometric, fatiguing knee-extensions at 30%, 50% and 70% maximum voluntary contraction (MVC) were performed by 18 healthy human subjects. Surface electromyographic (SEMG) activity was recorded from the mono-articular vastus medialis (VM) and vastus lateralis (VL) muscles, and the bi-articular rectus femoris muscle (RF). To make the bi-articular muscle work under (1) constant and (2) similar working conditions as the two mono-articulars do, the hip was fixed in a flexed position. The root mean square (RMS) SEMG recorded during fatigue was standardized to the respective values of MVC. The mean coefficients of regression of the RMS and median frequency (MF) changes were then analyzed by multivariate analysis of variance. RESULTS: The load effect upon the muscle fatigue changes, as measured by increase in RMS EMG, differed between the bi-articular muscle and the two mono-articulars, in that the parameter dropped with maximum load for the bi-articular, whilst it remained stable or even increased for the mono-articulars. This might suggest that the mono- and bi-articular muscles have different roles in fatigue tasks where the bi-articulars function purely as mono-articulars. By contrast, such a clear dichotomy between the bi-articular RF and the two mono-articulars, VM and VL, was lacking for the fatigue parameter of MF. CONCLUSIONS: As these findings were confined to the changes in RMS EMG, different neuronal coding mechanisms for the mono- and bi-articular muscles in the central nervous system may be inferred.

Adult

Calculation of multi-segment rigid body joint dynamics using MATLAB.

A computational model of the human upper limb was developed utilizing a matrix calculation software package (MATLAB) and a public domain suite of subroutines [Robotics Toolbox (1)]. An easily configurable model of a rigid body, serially linked manipulator was established, avoiding the need for complex numerical equations to be formulated. A generalized model of the upper limb was used to study throwing action of individual subjects by incorporating body segment parameters and kinematic data. Estimates of joint moments were calculated for multiple time instances. This technique can be utilized and adapted for modelling any arbitrary serially linked manipulator system. Inverse and forward kinematics and kinetics can be calculated, enabling biomechanical simulations to be undertaken.

Biomechanical Phenomena

Control of functional electrical stimulation with extended physiological proprioception.

The use of functional electrical stimulation (FES) of muscle for paraplegic locomotion, or grasp augmentation in tetraplegia, is limited by the variability in muscle response to stimulation as a result of several external and internal factors. Previous approaches to this problem have used position-servo controllers, which have been shown to function satisfactorily in the laboratory. However, such systems will fail should obstacles be encountered or should the stimulation hardware develop a fault. To prevent such potentially dangerous failures some form of sensory feedback is required. This paper describes the first application of a technique known as extended physiological proprioception (EPP) to the control of FES to compensate for muscle response variability and provide proprioceptive feedback via the appropriate sensory pathways. In the experimental system described, a paraplegic subject controlled the extension of his paralysed knee by shoulder protraction. A Bowden cable linked the two joints, and a dynamometer in this cable was used to derive the control signal for a computer-controlled stimulator which delivered surface stimulation to the quadriceps muscle group. Modelling and parameter identification were performed by analysis of the step response, and the controller was designed from consideration of the root locus. The advantages of the system, in terms of improved proprioceptive feedback and reduced limb-positioning error were assessed in a test of joint positioning accuracy with vision occluded. The EPP system showed improvements over both open and closed-loop position-servo controllers.

Artificial Limbs

Rhyme, rime, and the onset of reading.

There is recent evidence that children naturally divide syllables into the opening consonant or consonant cluster (the onset) and the rest of the syllable (the rime). This suggests an explanation for the fact that preschool children are sensitive to rhyme, but often find tasks in which they have to isolate single phonemes extremely difficult. Words which rhyme share a common rime and thus can be categorized on that speech unit. Single phonemes on the other hand may only be part of one of these speech units. This analysis leads to some clear predictions. Young children, even children not yet able to read, should manage to categorize words on the basis of a single phoneme when the phoneme coincides with the word's onset ("cat," "cup") but not when it is only part of the rime ("cat," "pit"). They should find it easier to work out that two monosyllabic words have a common vowel which is not shared by another word when all three words end with the same consonant ("lip," "hop," "tip") but the odd word has a different rime than when the three words all start with the same consonant ("cap," "can," "cot") and thus all share the same onset. The hypothesis also suggests that children should be aware of single phonemes when these coincide with the onset before they learn to read. We tested these predictions in two studies of children aged 5, 6, and 7 years. The results clearly support these predictions.

Child

Influence of walking speed on gait parameters.

Modern three-dimensional gait analysis systems give information on joint angles and moments in the sagittal and coronal planes, for which normal ranges may not be readily available in the literature. Since patients with joint disease tend to walk slowly and with a short stride, it is essential that normal ranges for gait parameters should be defined with reference to speed of walking. This we have done using a population of 10 normal male subjects aged from 18 to 63 years, walking at speeds which range from very slow to very fast. The ranges of knee angle and moment are given, together with the changes in these parameters with walking speed. Peak knee flexion moment is strongly related to walking speed, whereas coronal plane knee angle is virtually independent of it. The stride length is probably the best basis for deciding the normal range for a particular measurement.

Adolescent