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Biomedical subjects

C Knight

Publications and source records attributed to C Knight.

At least 91 records · Page 5Linked to original sources
PubMed1990

Use of support groups with adult female survivors of child sexual abuse.

Adult survivors of child sexual abuse suffer from a variety of interpersonal and intrapersonal problems. The support group, with its emphasis on self-help and mutuality, represents a potentially powerful form of intervention to assist survivors in dealing with their sexual abuse and the problems resulting from it. In this article, the author explores the use of this form of group work, including the unique role of the group leader, the value of a time-limited approach, the stages of group development, and treatment themes.

Adult↗
PubMed1988

Women's attitudes to withdrawal bleeding and their knowledge and beliefs about the oral contraceptive pill.

One hundred and fifty-eight attenders at general practices and family-planning clinics, and 20 young female doctors volunteered to complete a questionnaire about how women take the oral contraceptive pill, their knowledge of the Pill and their attitudes to withdrawal bleeding. Forty-three per cent of female patients has used the Pill to alter the time of withdrawal bleeding. Twenty-two per cent of female patients had taken the Pill daily for more than six weeks on at least one occasion and all reported positive experiences. However, 83% of female patients believed that it was necessary to bleed monthly when taking the Pill and 69% of the female patients believed that continuous use of active medication is undesirable. The over-all knowledge of the Pill was poor and 43% of female patients did not know what to do if they missed two consecutive Pills. Female doctors were better informed but had similar attitudes about the Pill to those of other women. Forty-six per cent of the female patients and 55% of young female doctors would chose to bleed at intervals of three months or greater if they could determine their own Pill regimen.

Adult↗
PubMed1988

Translocation 5;21 and interstitial deletion of chromosome 7 in a case of chronic myelomonocytic leukemia.

We report a case of chronic myelomonocytic leukemia with a translocation involving chromosome 5 and 21, namely, t(5;21)(q35.3;q22.1), and an interstitial deletion of the long arm of chromosome 7. High-resolution analysis at the 900-band stage has shown that the lesion in chromosome 7 is an interstitial deletion involving loss of the segments q22-q35 of the long arm of chromosome 7 and retaining the telomere.

Aged↗
PubMed1987

Self-expanding endovascular prosthesis: an experimental study.

A new type of endovascular prosthesis was inserted in 28 animals and evaluated for several factors, including thrombogenicity, tendency to migrate, critical implant zones, and incorporation into the vascular wall. The new prosthesis is a woven, multifilament structure of stainless steel alloy; its inherent elastic, self-expanding characteristics hold it against the vessel walls. Forty-seven endoprostheses (3-5 mm in diameter, 15-50 mm long) were percutaneously implanted with either a 6-F introducer sheath, a coaxial 9-F catheter, or a 0.014-inch (0.036-cm) guide wire into the femoropopliteal, coronary, carotid, and renal arteries and iliac veins. Anticoagulant or platelet antiaggregating agents were not used before or after implantation. Angiographic and histologic analyses showed that the prosthesis had a very low thrombogenicity when it was well adapted to the native vessel diameter and that it was incorporated into the vessel wall by a new intima by the 3d week after implantation. No migration occurred, and branch vessel flow was preserved even in those vessels in which ostia were traversed by the prosthesis. This prosthesis has potential for clinical application in the treatment of postangioplasty restenoses, particularly in the coronary arteries.

Animals↗
PubMed1985

Menstruation, menstrual protection and menstrual cycle problems. The knowledge, attitudes and practices of young Australian women.

The results of a survey of 1377 young Australian women aged 14 to 19 years, conducted to determine their attitudes, state of knowledge and practices with regard to menstruation, are presented. The young women, as a group, lacked sufficient information about menstruation, about the time of ovulation, about menstrual discharge, and about the use of tampons. A high proportion (80%) considered menstruation to be inconvenient or embarrassing. Certain measures aimed at remedial action are suggested.

Adolescent↗
PubMed1985

Menstruation as medicine.

Traditional healing rituals in many parts of the world seem to derive from a model of cyclical renewal provided in the first instance by menstruation. Health is seen as dependent upon a correct balance between polar opposite states such as 'heat' and 'cold','dryness' and 'wetness' etc. Nature seems to achieve such balance by alternating regularly between opposites such as night and day, wet season and dry. In this way, periodic 'death' (night, winter etc.) alternates with 'life'. The logic of healing rites is that humans, too, should be able to move through 'death' to 'new life' by keeping closely in tune with wider rhythms of renewal. It is argued here that ideally, women should achieve this by menstruating in synchrony with the moon, which periodically 'dies' and is 'reborn'. Failing this--runs the traditional logic--men themselves must learn to 'menstruate' in some symbolic sense in order to safeguard the rhythms of renewal.

Attitude to Death↗
PubMed1985

Screening for early diabetic nephropathy: which sample to detect microalbuminuria?

In a study to monitor the acceptability of using a timed overnight urine collection to measure microalbuminuria in a large diabetic population, it was found that only 184 (69.4%) of 265 diabetics returned the urine collection to the hospital laboratory. Three proposals for an initial screening test to predict high risk microalbuminuria were analysed. Proposal I: a random urinary albumin concentration (RAC) greater than 25 micrograms/ml predicts an overnight albumin excretion rate (AER) greater than 30 micrograms/min. In 159 diabetics, the sensitivity of this screening test was 56%, specificity 81%, and predictive value 15%. Proposal II: an albumin concentration greater than 20 micrograms/ml in an early morning urine sample predicts an overnight AER greater than 30 micrograms/min. In 175 diabetics, the sensitivity of this screening test was 86%, specificity 97%, and predictive value 71%. Proposal III: an albumin/creatinine ratio (albumin mg/l creatinine mmol/l) greater than 3.5 in an early morning urine sample predicts an overnight AER greater than 30 micrograms/minute. In 171 diabetics, the sensitivity of this screening test was 100%, specificity 95%, and predictive value 64%. It is concluded that an albumin/creatinine ratio performed on an early morning urine sample brought to the diabetic clinic would be a useful initial screening test to detect an overnight AER greater than 30 micrograms/min.

Albuminuria↗
PubMed1981

Transcutaneous oxygen and carbon dioxide monitoring. Use in adult surgical patients in an intensive care unit.

We evaluated a combined transcutaneous oxygen and carbon dioxide (tcPO2 and tcPO2) monitor in 33 adult surgical patients in an intensive care unit. Surgical procedures included cardiothoracic, general, vascular, and orthopedic operations. Ninety-three paired, transcutaneous values were compared with simultaneously determined arterial blood gas measurements. The correlation coefficient for PaO2 was .75 (P less than .01) whereas for PaCO2 it was .55 (P less than .01). Although statistically significant, individual transcutaneous values differed by as much as 50 mm Hg from levels determined from arterial samples. Such differences make it inappropriate to use this monitor to predict actual PaO2 or PaCO2. By contrast, continuous monitoring allowed observation of acute changes associated with respiratory-care procedures and cardiovascular decompensation. Such acute changes changes were appreciated on the tcPO2 tracing but not the tcPO2 tracing. We conclude that the tcPO2 monitor is a valuable trend indicator of cardiopulmonary dysfunction, but that the tcPCO2 monitor is not.

Adult↗