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Biomedical subjects

C Korthals

Publications and source records attributed to C Korthals.

9 recordsLinked to original sources
PubMed1984

[Acute pancreatitis].

The acute pancreatitis, especially the more severe cases with tissue necrosis, requires a high degree of intensive care monitoring and treatment. For the determination of the most suitable moment for surgical intervention, close cooperation between internist and surgeon is inevitable. The initial therapy is principally conservative; in especially severe cases and in cases of biliary pancreatitis, an early operation may be necessary, whereas in most cases of grade II pancreatitis, delayed surgery will be performed. Prerequisite for the success of any operation is optimal pre- and postoperative medical treatment.

Acute Disease↗
PubMed1981

[Therapy of hypertensive crises with a mono-substance with alpha- and beta-blocking properties (labetalol)].

For treatment of hypertensive emergencies 36 patients received an intravenous bolus of 100 mg labetalol. The mean blood pressure of the whole group was decreased from 220/128 mm Hg to 167/107 mm Hg. Mean heart rate dropped from 85 to 76 per minute. 7 patients did not respond to treatment. Thereafter 4 patients received a second dose of 100 mg or 500 mg labetalol respectively, whereupon 2 showed a distinct drop in blood pressure. Simple handling and intensive efficacy and the lack of troublesome side effects recommend labetalol for the treatment of hypertensive emergencies.

Adult↗
PubMed1980

[Results of computerized tomography of the skull in hemodialysis patients].

Psychiatric and neurological symptoms as well as the clinical diagnosis of 22 patients on chronic hemodialysis were set in contrast with the findings of the cranial computerized tomography. The cranial computerized tomography turns out to be a valuable diagnostic aid to recognise or exclude morphologic lesions in the central nervous system, particularly because the complex overlap of the various pathogenetic mechanisms in hemodialysed patients points out frequently the little value of the clinical symptoms.

Adult↗
PubMed1980

[Virus hepatitis B in hemodialysis wards: ways of distribution and possibilities of their interruption (author's transl)].

An attempt was made to describe differentiated problems in connection with virus hepatitis B in hemodialysis wards in a form as brief and precise as possible and to present some suggestions as to the elimination of this insidious disease. A through consideration of the hepatitis question yielding to a well established and legally sanctioned prevention concept would not only be of great importance to hemodialysis patients and their family members and the dialyses personnel but it would also play a great role for the protection of the general population. Finally, a statement by Baruch Blumberg (Nobel Price winner in Medicine, 1976) should visualize the universal importance of the hepatitis question once more: "If we succeeded in bringing hepatitis B under control, this would bring about a reduction of the rate of chronic liver diseases and of primary liver carcinoma."

Austria↗
PubMed1980

[The natural history of dialysis encephalopathy (author's transl)].

18 data with etiopathogenetic relations to the dialysis encephalopathy, such as plasma aluminum levels, parameters of azotemia and parathyroid function, blood pressure, IQ, and EEG-findings, were compared between 5 patients suffering with encephalopathy and 54 dialysis-patients without neurological symptoms. The investigations, including statistical computations (variance analysis, multiple linear regression, multivariate analysis) elicited the following results: 1. All patients suffering from encephalopathy showed higher plasma aluminum concentrations (505 +/- 58 microgram/L : 228.9 +/- 213 microgram/L, p = greater than 0.01), higher serum calcium levels (2.48 +/- 0.15 mmol/L : 2.35 +/- 0.11 mmol/L, p = less than 0.001), higher rates of osteopathy and abnormal EEG's (5 of 5 : 7 in 41 patients). 2. Age, duration of dialysis treatment, quality of dialysis treatment, blood pressure, did not show any pathogenetic influence. 3. Hyperaluminemia was caused by the oral administration of aluminum hydroxide. After reduction of the daily dose from originally 6.18 +/- 3.24 gm to 1.52 +/- 0.45 gm, the plasma aluminum levels decreased to 54.05 +/- 34.59 microgram/L without any adverse effects on the serum phosphate levels. The results suggest that dialysis-patients need less AI-OH than is usually indicated. 4. Encephalopathy did not occur after normalisation of plasma aluminum levels. 5. With respect to the aluminum toxicity in dialysis-patients, dialysis encephalopathy should not be classified as a complication of multifactorial etiology. Only hyperparathyroidism seems to be an additional risk factor.

Adult↗