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Biomedical subjects

C Kuehner

Publications and source records attributed to C Kuehner.

5 recordsLinked to original sources

[Stalking--what does the family doctor need to know?].

Stalking is a widespread phenomenon, which for the stalked person is associated with a not inconsiderable risk of becoming the victim of an act of violence. Furthermore, stalked persons may develop significant psychological problems, and therefore often seek out a doctor as their first contact. Another reason for this is the still unsatisfactory legal situation and widespread ignorance of the stalking problem on the part of the police and the courts. In the light of the above, it is of great importance that the physician should thoroughly familiarize himself with the problems associated with stalking.

Aggression↗

Gender differences in unipolar depression: an update of epidemiological findings and possible explanations.

OBJECTIVE: To give an update on epidemiological findings on sex differences in the prevalence of unipolar depression and putative risk factors. MATERIAL AND METHODS: Systematic review of the literature. RESULTS: Recent epidemiological research yields additional evidence for a female preponderance in unipolar depression, holding true across different cultural settings. Current explanations include artefacts, genetic, hormonal, psychological and psychosocial risk factors. Rather consistently, intrapsychic and psychosocial gender role related risk factors have been identified which may contribute to the higher depression risk in women. Gender role aspects are also reflected in endocrine stress reactions and possibly influence associated neuropsychological processes. CONCLUSION: There is a need for more integrative models taking into account psychological, psychosocial, and macrosocial risk factors as well as their interactions, which also connect these factors with physiological and endocrine responses. Furthermore, it is conceivable that across the life span, as well as across cultural settings, individual risk factors will add with varying emphasis to the higher prevalence of depression in women.

Adolescent↗

Gender differences in the short-term course of unipolar depression in a follow-up sample of depressed inpatients.

OBJECTIVE: This paper examined sex differences in the short-term course of depression and assessed the impact of possibly outcome-affecting factors, including sex-specific recall artefacts and demographic and clinical characteristics. METHODS: A cohort of 179 unipolar depressed inpatients was followed up 1 (T1) and 7 months (T2) after discharge. RESULTS: Residual depression at T1 was comparable in both sexes as was the rate of follow-up nonremissions in patients who had failed to remit from the index episode at T1. In contrast, female gender was a significant predictor of relapse. This sex difference was partly attributable to women who relapsed after T1 and were again in remission at T2. Potential sex-related recall artefacts were tested by contrasting the patients' retrospective assessment of their T1-depression status reported at T2 with their interviewer-rated depression status assessed at T1. Results suggest that the observed sex difference in relapses could neither be explained by memory artefacts nor by differences in demographic and clinical sample compositions. CONCLUSIONS: It is concluded that due to their higher risk for early relapses, particular efforts with regard to continuation treatment are required for women during the critical period of remission.

Adolescent↗

Responses to depression in unipolar depressed patients: an investigation of Nolen-Hoeksema's response styles theory.

BACKGROUND: The response styles theory suggests that rumination in response to depressed mood exacerbates and prolongs depression, while distraction ameliorates and shortens it. Gender differences in response styles are said to contribute to the observed gender differences in the prevalence of unipolar depression. While empirical support for the theory has been found from a variety of non-clinical studies, its generalizability to clinically depressed patient populations remains unclear. METHODS: A cohort of 52 unipolar depressed in-patients was assessed with the Response Styles Questionnaire during in-patient stay (T1) and 4 weeks after discharge (T2). The patients were followed up 4 months after discharge (T3). Clinical assessment included the SCAN-PSE-10. RESULTS: Moderate and statistically significant retest-stabilities for rumination and distraction were found, comparable for patients with stable and changing depression status from T1 to T2. A cross-sectional diagnosis of a major depressive episode was associated with rumination, while gender was not. Post-discharge baseline rumination (T2), adjusted for concurrent depression, predicted follow-up levels of depression (T3), and, in patients who were non-remitted at post-discharge baseline, it predicted presence of a major depressive episode at follow-up (T3). Results on distraction were more ambiguous. CONCLUSIONS: Our results suggest that rumination is likely to have a deteriorating impact on the course of clinical episodes of depression in unipolar depressed patients. Larger longitudinal patient studies are needed to validate these findings.

Adaptation, Psychological↗