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C L BAUGH

Publications and source records attributed to C L BAUGH.

5 recordsLinked to original sources
PubMed1964

EFFECTS OF BICARBONATE ON GROWTH OF PASTEURELLA PESTIS. I. DIFFERENTIAL RESPONSE OF VIRULENT AND AVIRULENT CELLS.

Surgalla, M. J. (Fort Detrick, Frederick, Md.), A. W. Andrews, and C. L. Baugh. Effects of bicarbonate on growth of Pasteurella pestis. I. Differential response of virulent and avirulent cells. J. Bacteriol. 88:269-272. 1964.-Virulent Pasteurella pestis and the avirulent mutants always present in a virulent inoculum have been demonstrated to give growth responses in opposite directions upon addition of bicarbonate to broth cultures under certain conditions. The effect of supplemental bicarbonate on initiation of growth from a virulent inoculum was found to be either stimulation of both virulent and avirulent cells at low levels of added bicarbonate, depression of both virulent and avirulent cells at higher initial concentrations, or depression of avirulent mutants with simultaneous stimulation of virulent cells at a narrow range of intermediate levels.

Animals↗
PubMed1964

EFFECTS OF BICARBONATE ON GROWTH OF PASTEURELLA PESTIS. II. CARBON DIOXIDE FIXATION INTO OXALACETATE BY CELL-FREE EXTRACTS.

Baugh, C. L. (Fort Detrick, Frederick, Md.), J. W. Lanham, and M. J. Surgalla. Effects of bicarbonate on growth of Pasteurella pestis. II. Carbon dioxide fixation into oxalacetate by cell-free extracts. J. Bacteriol. 88:553-558. 1964.-Enzyme preparations from Pasteurella pestis will carboxylate phosphoenolpyruvate to form oxalacetate by two distinct reactions. The reactions are similar to those catalyzed by the enzymes, phosphoenolpyruvic carboxylase and phosphoenolpyruvate carboxykinase. No significant differences in enzyme characteristics or enzyme content were found when virulent cells were compared with avirulent under the conditions of our experiments. The carboxykinase of P. pestis differs from that of animal origin, because it is dependent upon adenine derivatives rather than inosine or guanosine nucleotides. The latter two nucleotides can act indirectly by way of adenosine nucleotides, because nucleoside diphosphokinase and myokinase are present in the extract.

Acetates↗
PubMed1959

Photodynamic response in bacteria.

The photodynamic lethal response of Gram negative bacteria was found to be a one event phenomenon as previously reported. However, the kinetics of the lethal response in Gram-positive microorganisms was found to be more complex. The survivor response of the latter was dividable into at least two distinct parts, each of which could be influenced by various environmental and genetic factors. Some correlation was found between sensitivity or resistance to x-ray and ultraviolet radiations and sensitivity or resistance to photodynamic action.

Bacteria↗