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Biomedical subjects

C L Cazzullo

Publications and source records attributed to C L Cazzullo.

At least 109 records · Page 6Linked to original sources
PubMed1976

Further studies on the major histocompatibility complex as a genetic marker for schizophrenia.

Our results seem to indicate the existence of a locus in the major histocompatibity complex (MHC) region, correlated to schizophrenic illness and strictly linked to the loci HL-A and MLR. The associations found between these last loci and the disease can probably be explained by a linkage disequilibrium or a selective pressure between the allelles of the three loci. Our results also indicate that the genetic systems investigated may be useful diagnostically as a genetic marker for schizophrenia. But the real meaning of their relationships to the illness has to be further investigated.

Alleles↗
PubMed1975

[Technic and indications for acupuncture in psychiatry].

On the basis of personal experience in the People's Republic of China, Chinese Psychiatry and acupuncture are reviewed. The application technique is described and the syndromes in which it is most indicated discussed. Its association with psychodrugs is also considered.

Acupuncture Therapy↗
PubMed1975

Immunogenetics of the Lennox-Gastaut syndrome: frequency of HL-A antigens and haplotypes in patients and first-degree relatives.

Twenty-two patients with the Lennox-Gastaut syndrome and their families were examined for HL-A antigens by the microlymphocytotoxicity test. The antigen HL-A7 belonging to the HL-A locus showed a significantly increased frequency (p less than 0.0005) both in parents and in patients. The same antigen showed a significantly altered segregation in patients but a normal one in healthy siblings. Another antigen of the second HL-A locus, HL-A12, did not display a normal segregation in our patients, in whom it was nearly not represented.

Epilepsy↗
PubMed1975

Multiple sclerosis immunogenetics. A possible correlation with human leukocyte HL-A antigens.

To investigate the relationships of genotype to susceptibility to multiple sclerosis, 42 patients hospitalized into Multiple Sclerosis Study Center of The Milan Medical School were typed for 14 HL-A specificities: HL-A1, HL-A2 + W 28, HL-A3, HL-A10 + W 19, HL-A11, HL-A9 of the 1st Series and HL-A5, HL-A7, HL-A8, HL-A12, HL-A13 of the 2nd Series. The increased HL-A9 frequency found in a previous study has been confirmed. Moreover in the total of multiple sclerosis patients this deviation reaches a higher degree of significance (P less than 0.01) and one antigen HL-A10 + W 19 appears to be significantly decreased (P less than 0.01). No variations were found in HL-A3, HL-A7 frequencies.

Clinical Trials as Topic↗