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Biomedical subjects

C L Coblentz

Publications and source records attributed to C L Coblentz.

27 records · Page 2Linked to original sources
PubMed1989

Chronic lung diseases: specific diagnosis by using CT.

We evaluated patterns of abnormal lung parenchyma on CT scans in six specific chronic lung diseases and then applied those findings in the differential diagnosis of these lung parenchymal patterns in 56 subjects. There were 48 patients with chronic lung diseases (43 with histologic proof) consisting of usual interstitial pneumonia (n = 20), sarcoidosis (n = 16), lymphangitic carcinomatosis (n = 7), lymphangioleiomyomatosis (n = 2), drug toxicity (n = 2), and eosinophilic granuloma (n = 1). Including eight CT scans of normal control subjects, 56 CT scans were assessed independently by two readers (R1 and R2). Chest radiographs, most of which were obtained within 1 week of CT examination, were available in 48 of the 56 subjects. CT scans were evaluated for specific parenchymal features including disease distribution, lung distortion, thickening of bronchovascular bundles and polygon walls, bronchiectasis, cysts, and nodules, to determine the association of each abnormal feature with the different diseases. Diagnosis was then made from the overall CT appearance of the lungs and, on a separate occasion, from the appearance of the chest radiograph. The correct diagnosis was made from the CT appearance in 54 of 56 patients (R1) and in 50 of 56 patients (R2). Correct diagnoses were made from the chest radiographs in 42 of 48 patients (R1) and 43 of 48 patients (R2). We have identified features that are reproducible and useful when describing CT scans of patients with chronic lung diseases. Interpretation of the appearance of the lung on CT scans was accurate in diagnosing usual interstitial pneumonia, sarcoidosis, and lymphangitic carcinomatosis.

Chronic Disease↗
PubMed1988

Aspergillus terreus as a cause of invasive pulmonary aspergillosis.

A 70-year-old woman with nodular, poorly differentiated lymphocytic lymphoma is the third reported patient with invasive pulmonary aspergillosis caused by Aspergillus terreus. This case differs from the two previously reported in that neither neutropenia nor broad spectrum antibiotics preceded the infection. A terreus should not be dismissed as a laboratory contaminant in pulmonary specimens, especially those from immunosuppressed patients.

Aged↗
PubMed1988

Aortobronchopulmonary fistula complicating aortic aneurysm: diagnosis in four cases.

Aortobronchopulmonary fistula, a fistulous connection between the aorta and lung, is uniformly fatal in untreated cases. However, with early recognition and surgery, the survival rate exceeds 80%. We have had four patients with aortobronchopulmonary fistula, all of which resulted from thoracic aortic aneurysms (two after grafting of thoracic aortic aneurysms, one mycotic, one atherosclerotic). All four patients presented with hemoptysis. All four had a chest radiograph, which in two showed the aneurysm and in three showed airspace disease adjacent to the aorta. The aneurysm was shown by CT in one of two patients and by aortography in two of three patients. Neither CT nor aortography showed the fistula. Aortobronchopulmonary fistula was proved by surgery in two of the patients and by autopsy in the other two. A high index of suspicion is necessary to make the diagnosis of aortobronchopulmonary fistula. The diagnosis should be considered in patients who have minor or major hemoptysis, with either coexisting thoracic aortic aneurysms or history of thoracic aneurysm repair.

Adult↗
PubMed1988

Calcified intralobar pulmonary sequestration.

The radiologic features of intralobar pulmonary sequestration (ILPS) have been described and include the identification of a feeding systemic artery on computerized tomography. Radiographically demonstrated calcification is rare and has been described only three times. We describe a patient with an ILPS whose radiographic findings were unusual for two reasons. First, while computed tomography (CT) demonstrated a tubular structure, it did not enhance with contrast material and thus was not considered to be a feeding vessel. Pathological examination revealed that this vessel had undergone thrombosis with subsequent organization and calcification. This finding also explains the second unusual feature, calcification, seen both on a plain chest radiograph and CT.

Aged↗
PubMed1985

Pain after barium enema: effect of CO2 and air on double-contrast study.

One hundred fifty-one consecutive patients scheduled for double-contrast barium enema studies were assigned randomly to insufflation with either air or carbon dioxide (CO2) in a double-blind, prospective trial. Within 24 hours after the enema study, the patients were contacted by telephone by an interviewer, who completed a standard questionnaire. Radiographs from the enema studies were assessed for quality by two radiologists. Pain experienced after the procedure was graded from 0 (none) to 4 (severe). Clinically relevant (grades 2-4) pain was experienced by 30% of patients after insufflation with room air, compared with 11% of patients in whom CO2 was used for insufflation (P = .005). The mean pain score for CO2 was 0.4, and for room air, 1.2 (P less than .005). Although five patients experienced grade 4 pain after insufflation with air, no patient reported severe pain after CO2 insufflation. Post-evacuation films confirmed there was significantly less residual gas in the CO2 group. The quality of radiographs was equal in the two groups. CO2 has advantages for use in the double-contrast barium enema examination.

Air↗
PubMed1985

Resolution of myositis ossificans in a hemophiliac.

Hemophilic myositis ossificans at the site of previous hemorrhage is a well recognised entity. A phenomenon, not previously described, is gradual absorption of a well corticated heterotopic bone over a period of five-and-a-half years. We here report this happening in a patient.

Child↗
PubMedDate not supplied

MR imaging of stump neuroma.

Painful stump neuromas in the postamputation patient are difficult to diagnose and treat. We report a case in which magnetic resonance allowed precise preoperative diagnosis and localization of such a lesion. Magnetic resonance, with its ability for long axis imaging in the extremity, is ideally suited for the workup of stump neuromas.

Amputation Stumps↗