PubMed Health⌕ Search

Biomedical subjects

C L Gupta

Publications and source records attributed to C L Gupta.

16 recordsLinked to original sources
PubMed1980

Ureterocalycostomy for postpyelolithotomy stenosis after failure of intubated infundibuloplasty.

Extended pyelolithotomy for staghorn calculus in a uremic patient with solitary functioning kidney was followed by development of stenosis of the infundibulum draining the superior and middle calyces. Drainage of the lower calyx down the ureter remained intact. Intubated infundibuloplasty proved unsuccessful since scarring and occlusion promptly recurred. Anastomosis of the middle calyx to the ureter was then performed with good results. We believe this is the first reported case of ureterocalycostomy for providing drainage to the middle calyx without lower polar nephrectomy.

Adult↗
PubMed1978

Fatal complication of intravesical formalin during control of intractable hemorrhage from radiation cystitis.

Fatal acute tubular necrosis occurred in 1 patient in whom intravesical formalin was used to control massive persistent hemorrhage from radiation cystitis. A suggestion is made to monitor blood formic acid levels and institute prompt dialysis whenever these exceed 80 mg. per 100 ml. to avert such a catastrophe. Intravenous sodium bicarbonate appears to be indicated prophylactically in combating the associated metabolic acidosis due to absorbed formic acid.

Acute Kidney Injury↗
PubMed1977

Blow out of a colocystoplasty loop owing to bladder neck obstruction.

A case of blowout of the colonic segment of a colocystoplasty at its free end owing to late development of bladder neck obstruction is described. Prostatitis and secondary bladder neck contracture provided further hindrance to the already inefficient voiding mechanism and predisposed to the rupture of the decompensated bowel loop. This is an extreme example of proof that the colonic loop, except as an improved substitute for an ileal segment, cannot withstand high intraluminal pressures generated in the presence of bladder outlet obstruction.

Adult↗
PubMed1977

Topical or no anaesthesia for external urethral sphincterotomy in neurogenic vesical dysfunction due to spinal injury.

Considerable controversy exists regarding the ideal anaesthetic coverage for external urethral sphincterotomy in spinal injury patients with detrusor-sphincter dyssynergia. From this preliminary experience on 34 patients in whom this procedure was indicated and then attempted under topical (urethral instillation of 20 ml of 2 per cent Lignocaine jelly) or no anaesthesia, we are encouraged into believing that these patients may not require general or regional anaesthesia for this operation.

Aged↗
PubMed1977

Testicular degeneration and necrosis induced by chronic administration of cannabis extract in dogs.

UNLABELLED: 1. Daily administration of cannabis extract (12.5 mg/kg body wt. for 30 days) produced a complete arrest of spermatogenesis in dogs. Distinct degenerative effects were produced in the form of extensive fibrosis and exfoliation of the seminiferous elements. 2. RNA, protein and sialic acid contents of the testis and epididymides were reduced after cannabis extract administration, whereas, testicular cholesterol and enzyme phosphatase were elevated. 3. Serum transaminases were slightly elevated, whereas the alkaline phosphatase and haemoglobin/haematocrit values were in normal range. 4. Histophysiological examination of the liver did not show any damage. 5. Reduced androgen production was reflected in low levels of sialic acid in the testis and epididymides, and shrunken Leydig cell nuclei and luminal epididymal epithelium. 6. IN CONCLUSION: Cannabis extract at 12.5 mg/kg body wt. dose level did not cause severe damage to the vital organs but it produced an effective inhibition of spermatogenesis in male dogs in 30 days and thus induces an antifertility state. The possibility of an adverse effect of frequent marihuana use on male reproductive organ functioning in man is alarming.

Animals↗
PubMed1976

Uretero-diverticulostomy to provide efficient drainage of pyelocaliceal diverticlum without sacrificing functional renal parenchyma.

Dependent drainage of a lower pole pyelocaliceal diverticulum was achieved by uretero-diverticulostomy in eight patients who already had compromised renal function due to bilateral megaureters or posterior urethral valves. This procedure preserves all functional renal parenchyma and the ureteropelvic junction is left undisturbed. This is the first description of such a procedure for the treatment of lower polar pyelocaliceal diverticulum.

Adolescent↗
PubMedDate not supplied

Pedicled omental graft in repair of large, difficult vesicovaginal fistulae.

Large vesicovaginal fistulae, particularly those associated with urethral loss, present formidable repair problems. Omentum, recognized for its role in resolving abdominal infection, is successfully used for pedicle grafts in these complex situations. The authors present their experience in 25 cases, describing modifications of an earlier procedure.

Adolescent↗
PubMedDate not supplied

Effects of Danazol on the epididymal function in male langurs (Presbytis entellus entellus Dufresne).

Danazol (28 mg/kg body weight) was administered intramuscularly (i.m.) to intact langurs for a period of 48 days. Epididymides weight showed no significant change but tubular lumina were devoid of spermatozoa. These effects were reversible after 180 days of recovery period. Possible antiandrogenic action of the drug was evaluated by administering Danazol in conjunction with testosterone propionate (TP) (0.7 mg/kg body weight) to castrated langurs. Biochemical estimations for total protein and sialic acid contents showed a significant fall in all the treated groups. Whereas, alkaline phosphatase activity was increased in Danazol treated langurs and a decrease was noticed in castrates, which returned to near normal level after recovery period in intact and TP treatment in castrates. In conclusion, the present findings demonstrate that Danazol effectively suppressed the action of testosterone propionate in castrates. The inhibitory effects of Danazol on steroidogenesis in intact langurs might be due to biochemical interaction at subcellular system.

Alkaline Phosphatase↗