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Biomedical subjects

C L Hart

Publications and source records attributed to C L Hart.

59 records · Page 4Linked to original sources
PubMed1991

Relationships of structural dimensions to bench press strength in college males.

The purpose of this study was to determine the relationships between structural dimensions and bench press performance in college males. Members of required fitness classes (n = 170) were measured after 14 weeks of strength and aerobic endurance training. Anthropometric dimensions included upper arm and chest circumferences, upper and lower arm lengths, shoulder and hip widths, %fat, and height. Arm muscle cross-sectional area (CSA) was calculated from upper arm circumference corrected for triceps skinfold. Drop distance was measured from the bar to the pectoral muscles. Multiple regression analysis selected upper arm CSA, %fat, and chest circumference as the best items to predict bench press strength (R = 0.83; SEE = 11.6 kg). Cross-validation of the prediction equation on a similar sample (n = 89) produced an r = 0.74 between predicted and actual bench press (t = 0.53, p greater than 0.50). In a second cross validation sample (n = 57) who had trained more extensively with weights, the correlation between predicted and actual bench press was r = 0.57 (p less than 0.05). The prediction equations significantly (t = 6.59, p less than 0.01) underestimated bench press performance in the more extensively weight trained subjects. The results of this study suggest that bench press performance is related to structural dimensions in males and that extensive strength training may alter the relationship between size and strength.

Adult↗
PubMed1990

Dose-dependent reduction of myocardial infarct size with the perfluorochemical Fluosol-DA.

The perfluorochemical Fluosol-DA has been shown to reduce infarct size. However, the dose-response relationship of the agent is unknown. Because perfluorochemicals (PFC) can potentially saturate the reticuloendothelial system and decrease carbon clearance as well as cause a transient elevation in liver enzymes, the present study was conducted to determine the lowest effective dose. New Zealand White rabbits (n = 73) were randomly selected prior to infarction to receive 10, 15, 20, 25, or 30 ml/kg PFC or an equivalent volume of 5% dextran (control) intravenously. Animals underwent 30 minutes of coronary artery occlusion with PFC or dextran infused over a 30-minute period starting at 20 minutes into the occlusion. Animals were put to death at 24 hours and infarct size was determined histologically and quantitated by computerized planimetry. Neutrophil infiltration into the ischemic myocardium was evaluated semiquantitatively. No hemodynamic differences were noted within groups. Infarct size was similar to that of controls in animals treated with 10 or 15 ml/kg PFC. Significant infarct size reduction, however, was noted in animals treated with 20, 25, and 30 ml/kg PFC versus controls; (p = 0.05, 0.04, and 0.02, respectively). Maximal infarct size reduction was seen with 30 ml/kg PFC (35%). Neutrophil infiltration was significantly decreased in all groups treated with PFC. These results show that intravenous Fluosol-DA significantly reduces infarct size at a minimal dose of 20 ml/kg.

Animals↗
PubMed1987

Invasive bacterial disease in childhood: efficacy of oral antibiotic therapy following short course parenteral therapy in non-central nervous system infections.

Recommendations vary considerably for duration of parenteral therapy of common bacteremic infections in children. To assess the efficacy of the current standard of practice by private pediatric practitioners in Portland, OR, we reviewed hospital and clinic records of children older than 6 months of age with non-central nervous system bacteremic disease due to Haemophilus influenzae type b, Streptococcus pneumoniae, Neisseria meningitidis and Group A Streptococcus during 1981 to 1984. Diagnoses were: cellulitis (buccal/periorbital), 21; bacteremia without focus, 17; epiglottitis, 13; pneumonia, 7; and other, 4. The average duration (range) of fever (greater than 37.9 degrees C) was 1.8 days (0.5 to 21 days), that of parenteral therapy was 2.9 days (0 to 10 days) and that of oral therapy was 9.5 days (4 to 42 days). No complications of inadequate therapy assessed by clinical or microbiologic failure were reported in study patients. Our review suggests that in a private practice where compliance and accessibility of medical care are good, parenteral therapy for non-central nervous system bacteremic disease need be continued only until the child is afebrile for 24 to 48 hours; outpatient oral therapy should be provided to complete a 10- to 14-day total course of antibiotics. A lumbar puncture should be performed in bacteremic children to rule out occult meningitis.

Administration, Oral↗