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Biomedical subjects

C L Meneghini

Publications and source records attributed to C L Meneghini.

At least 37 records · Page 2Linked to original sources
PubMed1982

T gamma and theophylline-sensitive T lymphocytes in allergic contact dermatitis.

Two lymphocyte subpopulations, T cells bearing a receptor for the Fc fragment of IgG (T gamma) and theophylline-sensitive T cells, were investigated in 49 patients with allergic contact dermatitis (ACD) in the acute phase and compared with a control group. Patients with ACD had markedly reduced relative T gamma and theophylline-sensitive T lymphocyte levels, compared with normals (P less than 0.0005). The patients also showed reduced absolute T gamma and theophylline-sensitive T cells with respect to the controls (P less than 0.01). To determine whether decreased levels of T gamma and theophylline-sensitive T cells were related to the activity of ACD, the same T-cell subsets were determined in 10 of 49 patients after the clearing of the contact dermatitis. Both T-cell subpopulations were found within the normal range.

Adolescent↗
PubMed1982

A case of hibernoma in a child.

A rare case of hibernoma about the nipple in a 9-year-old boy is presented: the tumour was peculiar not only for the age and region, but also for its superficial, subepidermal site.

Child↗
PubMed1981

Contact allergy from propylene glycol.

Propylene glycol (PG) 20% in water was tested in a group of 400 subjects with eczematous contact dermatitis. In six inpatients (1.5%) reactions were recorded as considered positive according to the following criteria: 1. the relevant history of prolonged contact with PG-containing topical pharmaceutical and cosmetic preparations; 2. the reaction extended in time outside the area of application of the test substance, and persisted locally for several day; 3. a similar reaction was obtained on repetition of the test with a lower concentration of PG; 4. the prompt improvement in clinical manifestations of eczema on withdrawal of PG-containing topical preparations. With the PG concentration employed no irritant reactions were observed.

Adult↗
PubMed1980

The active E-rosette test in allergic contact dermatitis.

An active subpopulation of peripheral blood T-lymphocytes, characterized by rapid (5 min) rosette formation with sheep red blood cells (A-RFC), was measured in patients with acute allergic contact dermatitis. A significant rise in A-RFC occurred in these subjects. The number of total T cells was also increased in the same group of patients, but the percentage of increase was smaller than that found in A-RFC. The significance of A-RFC and their relationship to patient immunological status are discussed.

Adolescent↗
PubMed1980

Shoe contact dermatitis.

The incidence of contact allergy was studied in a series of 165 patients with eczematous dermatitis of the feet correlated clinically with shoe contact. Positive reactions to one or more substances were recorded in 108 patients (65.4%). Among the relevant sensitizers were chromium, paraphenylenediamine, paratertiary butylphenolformaldehyde resin and nickel, while the other allergens were benzocaine, neomycin, balsam of Peru, ethylenediamine and parabens. Allergic contact dermatitis of the feet can be prevented by recognition of the allergens responsible, control of hyperhidrosis and avoidance of topical allergens.

Dermatitis, Atopic↗
PubMed1979

Contact and microbial allergy in pompholyx.

Contact sensitivity to medicaments and other chemical allergens has been observed in about 30% of 364 patients with pompholyx. Pompholyx is a recurrent vesicular eruption which increases the incidence of contact sensitivity. The majority of patients tested by means of intradermal and cultural tests did not show any relevant finding on the microbial nature, allergic or not, of pompholyx.

Allergens↗