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Biomedical subjects

C L Mollerup

Publications and source records attributed to C L Mollerup.

6 recordsLinked to original sources
PubMed1987

Gastrointestinal hemorrhage due to fistula from aortic aneurysm. Case report.

Two cases of gastrointestinal bleeding due to aortic aneurysm with fistula to the duodenum are reported. When upper gastrointestinal fiberendoscopy rules out the commonest sources of bleeding but reveals no specific lesion, sonography is advisable. Accurate diagnosis and timely treatment are prerequisites for a successful outcome in this otherwise fatal condition.

Aged↗
PubMed1985

Upper gastrointestinal hemorrhage associated with pancreatitis.

In a two-year period from June 1981, two cases of acute upper gastrointestinal bleeding caused by pancreatitis were observed. In both cases the bleeding was caused by erosion of the gastric mucosa contiguous to, respectively, a pseudocyst and an abscess of the pancreas. Both patients were successfully treated with cystogastrostomy. Erosive bleeding from gastrointestinal mucosa adjoining pancreatic lesions may be a more common source of upper gastrointestinal bleeding than has hitherto been assumed.

Abscess↗
PubMedDate not supplied

Clinical applicability of an amino-terminal radioimmunoassay for determination of parathyroid hormone.

With a radioimmunoassay using hPTH 1-34 for antibody production, for radioiodination and as a standard, hPTH 1-34 was detectable (detection limit 40 pg/ml) preoperatively in peripheral blood in 14 of 29 patients with hyperparathyroidism, but in no controls. In all patients with parathyroid adenoma and detectable hPTH 1-34 preoperatively, the values fell after parathyroid surgery. Contrastingly, three of four patients with diffuse parathyroid hyperplasia and two of three with normal parathyroid glands showed a rise in hPTH 1-34 postoperatively, which was concomitant with very low serum calcium levels. In studies of hPTH 1-34 in central venous blood (3 patients), levels were detectable in all samples, but not in simultaneously drawn peripheral blood. Values for hPTh 1-34 in central blood correlated to PTH determined from a bovine assay, but the peripheral samples showed no correlation. The low levels of circulating N-terminal immunoreactivity in peripheral blood make this assay inapplicable for routine diagnostic purposes. These low levels are due not only to low secretion rates, but also to rapid peripheral metabolization.

Adolescent↗