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Biomedical subjects

C L Reynolds

Publications and source records attributed to C L Reynolds.

15 recordsLinked to original sources

The measurement of health in nursing research.

Health, a concept central to the discipline of nursing, was investigated to determine how it is operationalized in the nursing research literature. It was found that, in spite of extensive admonitions in most theoretical guides (which otherwise vary) not to do so, nurse researchers most often characterize health in research as the absence of illness, disability, or symptoms, and they frequently ignore multiple dimensions, eg, physical, mental, or sociological aspects, as well as the reliability and validity of the measures when assessing the health of subjects. Suggestions for advancing research on the concept of health consistent with theoretical beliefs are offered.

Health↗

Lung carcinoid with Cushing's syndrome: control of serum ACTH and cortisol levels using SMS 201-995 (sandostatin).

Two patients with Cushing's syndrome due to lung carcinoid tumours were given the long-acting somatostatin analogue SMS 201-995 (Sandostatin). One received a single 50 micrograms dose which produced a 50% reduction in circulating ACTH levels within 4 h. The other has been maintained in clinical and biochemical remission for 10 weeks on 100 micrograms tid. This is the first report of the successful use of SMS 201-995 in carcinoid-induced Cushing's syndrome, and suggests that this hormone analogue could be valuable in the long term medical management of such patients.

Adrenocorticotropic Hormone↗

A new total substitute urinary bladder.

A surgical technique for the creation of an antireflux reservoir type substitute urinary bladder using the distal part of the ileum and aimed at meeting the demands expected of its normal counterpart is presented. Two male patients who underwent radical cystoprostatectomy with pelvic node dissection without urethrectomy for transitional cell carcinoma of the bladder are discussed herein. Variations in the creation of the reservoirs in both patients are described and the preliminary results reported.

Carcinoma, Transitional Cell↗

Thermodynamic considerations of the setting reaction in Ag3Sn amalgams.

The setting reaction of Ag3Sn amalgams may be thought of as a liquid phase sintering problem in which the reactants seek to form products with the lowest thermodynamic potential. We discuss the thermodynamic and kinetic considerations of this reaction. The lowering of free energy has been given as the reason for the formation of the gamma1, gamma2,and beta1 phases and a qualitative reaction coordinate diagram has been hypothesized. The barrier height for the formation of the beta1 phase has been determined to be 137 kJ/mol.

Dental Alloys↗