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Biomedical subjects

C L Sharma

Publications and source records attributed to C L Sharma.

5 recordsLinked to original sources

A polystyrene based membrane electrode for cadmium(II) ions.

A polystyrene based membrane of 3,4:12,13-dibenzo-2,5,11,14-tetraoxo- 1,6,10,15-tetraazacyclooctade-cane shows a Nernstian response to Cd(II) ions over a wide concentration range (3.16 x 10(-6) - 1.00 x 10(-1) mol L(-1) with a Nernstian slope of 29.8 mV/decade of concentration, between pH 2.0 and 6.0. This electrode has been found to be chemically inert and of adequate stability with a response time of 20s. The electrode gives reproducible results with a lifetime of 130 days. The membrane works satisfactorily in a partially non-aqueous medium up to a maximum 35% (v/v) content of methanol and ethanol. The practical utility of the proposed chemical sensor has been observed by using it as end-point indicator in the titration of Cd(II) ions with EDTA. The potentiometric selectivity coefficient values indicate that the membrane sensor is highly selective for Cd(II) ions over a number of cations. Small amounts of surfactants do not disturb the functioning of the sensor. This electrode has also been used to estimate cadmium ions in real samples.

Cadmium↗

Nonresective alternative for the cure of nongangrenous sigmoid volvulus.

PURPOSE: Recurrence in sigmoid colon volvulus is a very vexing problem, because it occurs after all types of treatment including a resection of the sigmoid. A nonresective procedure that prevents recurrence in the long term has been devised and tried during the period 1968 to 1992. METHODS: The procedure involves extraperitonealization of the whole sigmoid colon via a left paracolic gutter incision in a manner akin to an extraperitonealized colostomy and placing it in the left half of the infraumbilical abdominal wall. This article presents a study of 84 patients who underwent this operation and who were followed-up. Some very useful practical points for ensuring the success of the procedure are also presented. RESULTS: The subjects comprised 58 male and 26 female patients, aged 10 to 81 (median, 60) years. The operating time ranged from 40 to 70 (median, 50) min. The operative mortality (9 percent) and morbidity of the procedure including cardiopulmonary complications (7 percent), incidence of small-bowel obstruction (1 percent), and incisional hernia formation (2.3 percent), were reasonably low. The incidence of wound-healing problems was significantly (P < 0.02) reduced in the 1980s and 1990s. Seventy-six patients were available for follow-up ranging from 0.5 to 25 (mean+/-standard error, 6.671+/-0.573; median, 6) years. Forty-eight patients were followed-up for five or more years. No patients developed recurrence of volvulus during the entire follow-up period. CONCLUSIONS: This nonresective, recurrence-free procedure provides a cure for nongangrenous sigmoid volvulus. It may be performed safely, even in relatively poor-risk patients, with acceptably low morbidity and mortality rates.

Adolescent↗

Massive necrosis and perforation of the colon in amebiasis.

A successfully treated case of acute fulminating necrotizing amebic colitis characterized by signs of toxemia, septicemia and peritonitis is reported. Early diagnosis and staged surgical procedures apparently lower the mortality. Intensive antiamebic therapy should be instituted as soon as amebiasis is confirmed, otherwise surgical therapy is likely to fail.

Acute Disease↗

Double gall bladder with two disease processes.

A double gall bladder is a rare congenital anomaly which is usually diagnosed by preoperative ultrasonography. Either one, or both lobes, of the double gall bladder, may be diseased. We report a patient in whom the two lobes were affected by different disease processes, namely, cholesterosis, and cholelithiasis with mucocele.

Adult↗