PubMed Health⌕ Search

Biomedical subjects

C L Trempe

Publications and source records attributed to C L Trempe.

At least 109 records · Page 6Linked to original sources
PubMed1984

Retinal pigment epithelium decompensation. I. Clinical features and natural course.

We studied 97 eyes (73 patients) that showed a sharp contrast between the grossly normal appearance of the posterior pole by funduscopy and the fluorescein angiography findings of multiple patches of retinal pigment epithelium (RPE) transmission defect in the early transit, associated with focal areas of RPE staining in the late transit. The staining was located primarily at the superior edge of the RPE defect (63 eyes). The average age of the patients was 52.2 years at the time of diagnosis, and the ratio of men to women was 3.5 to 1. Ocular histories were unremarkable, except for 27 eyes with documented central serous retinopathy. Thirty-two consecutive eyes have been followed for an average of 3.9 years, and 30 of those eyes have shown visual deterioration.

Adult↗
PubMed1984

Natural history of choroidal neovascularization in degenerative myopia.

We studied 354 eyes with myopic chorioretinal degeneration by means of standard clinical evaluation and fluorescein angiography. The eyes were classified on the basis of the degree of chorioretinal degeneration found in the posterior pole. Lacquer cracks (breaks in Bruch's membrane) were noted in 82% of the 149 eyes with choroidal neovascular membranes (CNM) and in 96% of the 58 eyes with isolated subretinal hemorrhages. These hemorrhages were reabsorbed without adverse visual sequelae in 32 eyes that were followed; in 14 of these eyes that were followed closely, the average time of reabsorption was 6.4 weeks. Seventy eyes with CNM were followed for an average of 40.9 months. In 96% of these eyes the CNM remained stable or regressed, leaving an atrophic, nonexudative scar. This study indicates that CNM in degenerative myopia is usually self-limited.

Adolescent↗
PubMed1984

Retinal pigment epithelium decompensation. II. Laser treatment.

Forty-one of 97 eyes with retinal pigment epithelium decompensation (RPED) were treated with monochromatic green argon laser photocoagulation to the focal area of RPE staining detected in the late fluorescein transit. Nineteen eyes were treated because of progressive visual deterioration. The other 22 eyes already had visual acuities of 20/50 or worse. Vision stabilized or improved in 34 eyes (82.9%) after an average of 1.6 years following treatment, compared with improvement in only 5 of 56 untreated eyes after an average follow-up period of 2.1 years. After an average follow-up of 7.1 years, 12 of 97 eyes with RPED developed choroidal neovascularization (9 spontaneously and 3 after photocoagulation) in the area where late RPE staining had been observed.

Adult↗
PubMed1984

Ultrasonographic findings in endophthalmitis.

Ultrasonographic findings in 11 cases of endophthalmitis are presented. Anterior vitreous echoes and thickening of the retinochoroidal layer were constant findings. Posterior vitreous echoes were seen in nine of the cases, posterior vitreous detachment in seven, and vitreous membrane formation in six. Although vitreous echoes and thickening of the retinochoroidal layer are seen--singly or together--in various conditions, when these findings are present in a patient with signs and symptoms suggestive of infection, the suspicion of endophthalmitis is strong.

Adult↗
PubMed1984

A- and B-scan characteristics of shifting fluid level.

A shifting fluid level (SFL) was detected by A- and B-scans in 155 eyes. All eyes had a hemorrhage into the vitreous. In 129 of the 155 eyes (83%) the vitreous hemorrhage resulted from proliferative diabetic retinopathy. In 11 (7%) and seven eyes (5%), respectively, the hemorrhage was a complication of closed vitrectomy and scleral buckling procedures. In eight eyes (5%), the hemorrhage resulted from severe penetrating ocular trauma. The SFL was characterized by a high-amplitude echo on A-scan, and straight horizontal or vertical linear echo on horizontal or vertical B-scan, respectively. It showed a typical shift toward the most posterior portion of the globe when the eye was moved in the different positions of gaze. The SFL was overlying the retina in 150 eyes (97%) and was suspected to be subretinal in five eyes (3%). SFL represented a layer of sedimented red blood cells on the surface of the retina or choroid.

Adolescent↗
PubMed1984

Chronic macular edema in retinal branch vein occlusion: role of laser photocoagulation.

We used the monochromatic green argon laser to treat 41 eyes with retinal branch vein occlusion (RBVO) and decreased vision because of chronic macular edema of at least six months duration after the onset of RBVO. The average follow-up period after treatment was 19 months. Cystoid macular edema (CME) occurred in 34 eyes and noncystoid macular edema in seven eyes. In eyes with chronic CME we decreased intracapillary pressure in the portion of the macula drained by the occluded vein by segmental retinal arteriolar narrowing using photocoagulation to the retinal arterioles that perfused the involved portion of the macula. Partial or complete resolution of macular edema occurred in 27 eyes. Vision improved in 19 eyes and was stabilized in seven eyes. In eyes with chronic noncystoid macular edema treatment consisted of focal closure of leaking microaneurysms and retinal telangiectasias with photocoagulation. Closure of these leaking vessels associated with partial or complete resorption of hard exudates that had accumulated in the macula secondary to the leakage occurred in six of the seven photocoagulated eyes. Vision improved in four eyes and was stabilized in two eyes.

Aged↗
PubMed1984

Visual acuity related to retinal distance from the fovea in macular disease.

The visual potential of patients with macular diseases involving the fovea has not been adequately documented. We evaluated 55 eyes of patients having discrete macular lesions and related best visual acuity to retinal distance from the fovea. Best visual acuity in the parafoveal area extending from the center of the fovea to a distance of 0.25 disk diameters (DD) away was 20/25 to 20/50; from 0.25 to 0.5 DD, 20/50 to 20/100; from 0.5 to 0.75 DD, 20/100 to 20/200; from 0.75 to 1.0 DD, 20/200 to 20/400; and greater than 1.0 DD, counting fingers. The clinical importance of the findings as they relate to the rationale of laser treatment of macular lesions and to the evaluation of the low-vision is discussed.

Adult↗
PubMed1983

Choroidal neovascularization in fellow eyes of patients with advanced senile macular degeneration. Role of laser photocoagulation.

Choroidal neovascularization in fellow eyes of patients with advanced disciform macular scars usually has an unfavorable prognosis. Fifty-two such fellow eyes were treated, using the monochromatic green argon laser. The neovascular membranes were foveal in 24 eyes, juxtafoveal in ten eyes, and perifoveal in 18 eyes. Complete closure of the choroidal new vessels after treatment was seen in 46 eyes. Only one eye in the foveal group and five eyes in the juxtafoveal group had residual new vessels. After an average follow-up period of 16 months, improvement or stabilization of vision was seen in 36 eyes--18 eyes in the foveal group, four in the juxtafoveal group, and 14 in the perifoveal group. In view of the rewarding anatomical and functional results, photocoagulation, using the monochromatic green argon laser, should be considered in these high-risk eyes. Treatment of foveal neovascular membranes seems to be indicated if the visual acuity is 20/70 or worse.

Aged↗
PubMed1983

Management of choroidal neovascularization within the foveal avascular zone in senile macular degeneration.

After fluorescein angiography, central visual field testing, and photofield mapping, 94 eyes with senile macular degeneration and foveal choroidal new vessels (distance of 200 micron or less from the center of the foveal avascular zone) were treated with the monochromatic green argon laser. By the end of the follow-up period (average follow-up, 15 months), the new vessels were closed in 88 eyes and visual acuity was stabilized or improved in 70 eyes. These 70 eyes included 68 of 80 eyes with preoperative visual acuities of 20/70 or worse and only two of 14 eyes with preoperative visual acuities of 20/60 or better. Visual acuity was stabilized or improved in 55 of 62 eyes in which the foveal edge of the choroidal new vessels was within the margins of the pretreatment scotoma and in only 15 of 32 eyes with foveal edges extending beyond the scotoma margins.

Choroid↗
PubMed1983

Biomicroscopic study of the vitreous in macular breaks.

The vitreous in 74 eyes with macular breaks was studied using the El Bayadi-Kajiura preset lens mounted on a slit lamp. Fifteen of the eyes had macular breaks secondary to various causes, and 59 eyes had idiopathic senile macular breaks. Vitreous traction, indicated by the presence of opercula or visible vitreous strands, was present in 29 (49%) of the idiopathic cases. In 17 of 31 eyes without posterior vitreous detachment (PVD), an operculum was seen. In these eyes, intravitreous traction was suspected to be the cause of macular breaks. Opercula were seen attached to the posterior hyaloid membrane in six of the nine eyes with partial PVD. An operculum corresponding to the macular break was observed on the posterior hyaloid membrane in only five of 19 eyes with complete PVD. Of the 15 eyes with macular breaks secondary to various causes, complete PVD was seen in 10 eyes, one of which had an operculum. One eye had no PVD, and four eyes had partial PVD. Opercula were detected in two of the latter eyes. In one eye of the senile group and one eye of the secondary group, partial PVD caused traction at the edges of the macular break, resulting in retinal detachment.

Adult↗
PubMed1983

Vitreous floaters.

The vitreous changes in 148 eyes with sudden onset of floaters were evaluated biomicroscopically and documented photographically using an El Bayadi-Kajiura aspherical preset lens mounted on a photo slit lamp. Posterior vitreous detachment (PVD) was found in 83% of the eyes. In those eyes, the primary causes of floaters were prepapillary glial tissue on the posterior hyaloid membrane and minimal vitreous hemorrhage. In eyes with no PVD, intravitreous fiber-like opacities corresponding to the patient's symptoms were present in the posterior vitreous cavity near the retina. These opacities were found on the plicated membranes of Cloquet's canal, or were associated with liquefaction of the gel. The symptoms of patients 50 years of age or older were related to the acute onset of PVD in 95% of the cases. The complaint of multiple small floaters was frequently associated with vitreous hemorrhage and retinal breaks.

Adult↗
PubMed1983

Ultrasonographic findings in eyes with giant retinal tears and opaque media.

A preoperative diagnosis of giant retinal tear was suspected as a result of ultrasonography in six eyes with opaque media, and the diagnosis was then confirmed during surgery. All eyes showed a discontinuity in the high amplitude linear retinal echo, representing the location of a retinal tear involving more than one retinal quadrant. In five eyes there was a double linear echo attached to the optic nerve. The linear echo that was discontinuous with the contour of the globe corresponded to the inverted posterior flap of the giant retinal tear. The linear echo that was continuous with the contour of the globe represented detached retina. The preoperative discovery of a giant retinal tear by ultrasonography in eyes with opaque media influences the subsequent management of the patient.

Adult↗
PubMed1983

Tractional detachment of the macula following branch retinal vein occlusion.

In two patients, a detachment of the macula occurred following a branch retinal vein occlusion. Vitreoretinal relationships were investigated and documented by biomicroscopic photography. Both eyes showed partial posterior vitreous detachment with dense adhesions to a preretinal membrane at the macula. Vitreous contraction and traction appeared to be responsible for the detachment.

Aged↗
PubMed1982

Prognostic value of vitreous findings in diabetic retinopathy.

We examined the vitreous in 163 eyes with diabetic retinopathy using a +58.6-diopter aspherical preset lens and a slitlamp. Sixty-eight eyes had no vitreous detachment, 76 eyes had partial vitreous detachment, and 19 eyes had complete vitreous detachment. This article studies the vitreoretinal relationship to determine its role in the progression of proliferative diabetic retinopathy. We found that partial vitreous detachment with vitreoretinal traction is a major risk factor for progression of proliferative diabetic retinopathy, whether or not photocoagulation is performed. With complete vitreous detachment or with no vitreous detachment, the absence of vitreous traction protects against the progression of proliferative diabetic retinopathy.

Adult↗
PubMed1982

Macular photocoagulation. Optimal wavelength selection.

Relative merits of different laser wavelengths for macular photocoagulation are analyzed in terms of light scattering and light absorption in hemoglobin, melanin, and macular xanthophyll. Disadvantages of inner retinal damage in the macula caused by the blue-green argon photocoagulators in standard clinical use are discussed, along with advantages of argon green and krypton yellow light. Results of treatment of subretinal neovascularization in disciform macular degeneration are presented. A repetitive treatment, close follow-up protocol was employed with the objectives of closing neovasculature and preserving central visual field. In 74 successive patients treated with monochromatic argon green radiation, neovasculature was closed in 93%, central visual field loss was reduced or stabilized in 76%, and visual acuity was improved or stabilized in 70%. Results were analyzed in terms of location and size of the neovascular membrane, and it was found that best results were obtained with neovascularization farther than 600 microns from the foveola and smaller than 2 mm2. In 17 patients with neovascular membranes more than 600 microns from the foveola, neovasculature was closed in 100%, central visual field loss was reduced or stabilized in 94%, and visual acuity was improved or stabilized in 88%. Similar results were obtained with monochromatic krypton yellow radiation.

Humans↗
PubMed1982

Retinal localization of scotomata by scanning laser ophthalmoscopy.

The scanning laser ophthalmoscope (SLO) system has been modified to permit direct retinal perimetry. A movable pinhole in a retinal conjugate plane furnishes a mapping stimulus whose retinal locus is directly observable on a video image of the fundus. Scotoma maps in patients with macular disease and physiologic scotomata associated with normal optic discs are presented. Clinical applications of the method are discussed.

Humans↗