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Biomedical subjects

C L Wallace

Publications and source records attributed to C L Wallace.

5 recordsLinked to original sources
PubMed1999

The effect of surgery upon the quality of life in snoring patients and their partners: a between-subjects case-controlled trial.

Snoring is a common complaint in the community. Its psychosocial effect upon the relationship between sleeping partners is not known. This study examines prospectively by detailed tailored questionnaires the differences in the physical, psychological and social aspects in 27 snoring patients and their partners presenting to a snoring clinic and compares them with a control group of 24 patients who had undergone successful Laser-Assisted Uvulopalatoplasty (LAUP) and their partners. All areas examined showed improvement in the non-snoring group, particularly for the patient. Improvement was demonstrated in the non-snoring group's quality of marital state (P < 0.01). Quality of life was improved (P < 0.05). Perceived inadequacies in support were significantly higher in the snoring group (P < 0.05). Evidence of psychiatric disorder apparent in the snoring group was not present in the control group (P < 0.01). This is the first study to demonstrate significant improvement in the quality of life in both patients and their partners, after successful surgery for simple snoring.

Case-Control Studies↗
PubMed1997

Discovering common ground: the future of health, healing, and environment.

An ongoing project addressing relationships among and between nursing, health, healing, and environment gave rise to a future search conference. The conference goal was to describe a preferred future for health, healing, and environment and to devise action plans to realize it. Direction and focus were provided by the questions, "How do we want to be cared for?" and "How do we want to give care?" Outcomes, derived consensually, include a mission statement, long- and short-term goals, and a minimalist organizational structure.

Environment↗
PubMed1995

Nursing as the promotion of well-being: the client's experience.

An essential question of the discipline of nursing is: What do nurses do to promote the client's well-being? Using a phenomenological-hermeneutic approach to inquiry, this study explored the client's experience of nursing as the promotion of well-being, explicating in three distinct metathemes the meaning of well-being as transforming and nursing as caring. Based on this critical view of nursing, prospective directions for education, research and practice are suggested.

Adaptation, Psychological↗
PubMed1989

Vascular myosin expression during cytokinesis, attachment, and hypertrophy.

Primary cultures of canine saphenous vein smooth muscle cells downregulate the expression of the two muscle myosin heavy chains (mMHC) and upregulate the expression of a nonmuscle myosin heavy chain (nmMHC) when maintained in medium containing 10% fetal calf serum (FCS). The cellular function and control of these changes in contractile protein expression are not known. The purposes of these experiments were to determine whether the expression of nmMHC was required for cytokinesis, whether cell attachment stimulated nmMHC expression, and whether during changes in total myosin production the relative amounts of the two mMHCs remained constant. Primary cultures were maintained in FCS, in a serum-free defined medium (SFM), or after 2 days in SFM switched to FCS to induce proliferation and changes in myosin expression. nmMHC expression occurred before cytokinesis if cells were placed directly in FCS, whereas it occurred after cytokinesis if growth-arrested cells were exposed to FCS. The position of the cell in the cell cycle was responsible for these differences, and the temporal correlation of cell-cycle progression and nmMHC expression indicated that expression occurred during G1. Cells that remained unattached in the presence of FCS or attached in SFM did not express nmMHC. During net production or loss of mMHC by growth in SFM or FCS, respectively, the relative amounts of the two mMHC remained constant. These results suggest that 1) the expression of nmMHC requires the combined effect of FCS and attachment, 2) it occurs in cells progressing through G1 but is not required for cytokinesis, and 3) during changes in net myosin production, the two mMHC are coregulated.

Animals↗