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Biomedical subjects

C Lam

Publications and source records attributed to C Lam.

97 records · Page 6Linked to original sources

Transperineal versus transvaginal color Doppler imaging of the uterine circulation.

Transperineal sonography has been described as being useful in assessing patients in special clinical situations such as posterior placenta previa, preterm labor, stress incontinence, and vaginal atresia. We explored the feasibility of this approach in assessing the uterine circulation in 54 subjects, of whom 36 were postmenopausal. We found that visualization of the uterine artery by the transperineal approach was satisfactory in most patients. The uterine arterial Doppler indices obtained from this approach were compared with those obtained by the transvaginal route. Highly significant correlations were found (correlation coefficient tau for pulsatility index = 0.74, p < 0.0001). No significant differences in results between the two approaches were detected using the Wilcoxon Matched-Pairs Signed-Rank test. We conclude that transperineal Doppler studies of the uterine circulation are possible and may be useful in certain patient groups.

Adult↗

Opsonic activity of the alternative complement pathway in infected human intra-abdominal fluid.

The complement-mediated opsonic activity (CMOA) in intra-abdominal exudates collected during laparotomy from peritonitis patients was examined by an in vitro phagocytic bactericidal assay. It was found that infected intra-abdominal exudates barely promoted detectable killing of Escherichia coli 01 by polymorphonuclear leukocytes. Only the minority of bacteria recovered by differential centrifugation from the infected exudates had C3 on their surfaces. Such bacteria were not optimally opsonized in vivo, whereas they became fully coated with C3 during a brief incubation in vitro in normal human serum. The low level of CMOA in the peritoneal fluid paralleled a depletion of complement in the peripheral blood. Thus, in cases complicated by sepsis with gram-negative bacteria, the CMOA in the blood was extremely low. These data suggest that the high susceptibility of the peritoneum to infection by gut flora, despite the normal phagocytic response, may be partly explained by the low local level of functional complement which is inadequate for optimal opsonization of the bacteria.

Adult↗

Methodologic aspects of tympanometry in cats.

The tympanometric effects of the methodologic variables of direction and rate of pressure change were studied in cats. Tympanogram morphologic findings differed between ascending and descending pressure runs, with the descending ones being simpler in configuration and less influenced by the rate of pressure change. The stability of tympanograms to repetitive testing was examined in the same cats, and five human subjects. Acoustic admittance increased sequentially during the first three pressure sweeps of a repetitive testing sequence in a majority of both groups.

Acoustic Impedance Tests↗

Particle effects on ultraviolet disinfection of coliform bacteria in recycled water.

Pilot- and bench-scale coliform inactivation tests with UV irradiation were used to show how suspended solids remaining in filtered secondary effluent affect the efficiency of the UV disinfection process. Observed kinetic inactivation rates decreased with increasing suspended particle sizes of 7 microm or larger present in tertiary effluent. First-order inactivation rates estimated from collimated beam dose-response curves for discrete ranges of UV doses were substantially different, which should caution researchers not to compare inactivation data obtained with largely dissimilar UV doses or suspended particle distributions. A dose of approximately 800 J/m2 was identified as the minimum dose that will consistently meet the California wastewater reclamation coliform criterion when applied to in-line filtration effluent.

Conservation of Natural Resources↗

Treating urinary incontinence in a head-injured adult.

The purpose of this study was to determine the effects of four behavioural procedures in helping a head-injured adult to control diurnal and nocturnal enuresis. A multiple baseline, single subject research design was utilized to test the effectiveness of those procedures. Data were collected for a period of seven months, including four months of baseline and intervention, and three months of follow-up. Results showed that the frequency of urinary incidents was reduced to zero at the end of the treatment and follow-up periods. Implications of the research data for future studies about urinary incontinence in head-injured patients are discussed.

Activities of Daily Living↗