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Biomedical subjects

C Landy

Publications and source records attributed to C Landy.

5 recordsLinked to original sources
PubMed1998

Nandrolone decanoate for men with osteoporosis.

To compare the efficacy and safety of nandrolone decanoate and calcium (NDC) with those of calcium alone (CAL) in men with idiopathic osteoporosis, a 12-month, randomized, prospective, controlled study, was performed in an outpatient clinic. Twenty-one men with idiopathic osteoporosis (as determined by radiological and dual energy x-ray absorptiometry findings) were randomly allocated to either 50 mg nandrolone decanoate intramuscularly (im) weekly and 1,000 mg oral calcium carbonate daily (NDC group) or to 1,000 mg oral calcium carbonate daily (CAL group). Bone densitometry (total body, left femur, and lumbar spine), serum, and urine biochemical parameters were measured at 3-month intervals. In the NDC group, bone mineral density initially increased, reached a plateau, and then decreased to near baseline levels at 12 months. Increases in lean muscle mass mirrored these changes. Free and total testosterone significantly decreased. Hemoglobin increased in all patients in this group. Patients in the CAL group exhibited no significant change in either total body or bone mineral density or biochemical parameters. Thus, nandrolone decanoate, 50 mg im weekly, transiently increases the bone mass of men with idiopathic osteoporosis in this preliminary study. Careful monitoring is necessary.

Absorptiometry, Photon↗
PubMed1997

Factors influencing the accuracy of home blood pressure measurement.

BACKGROUND: Hypertension is a common disorder, affecting approximately 50 million Americans. Because many people have this disorder and its sequela, it is important not only to detect hypertension but also to monitor adequacy of control. Over the past few years, blood pressure monitoring devices (BPMDs) have become available for individuals to measure their blood pressure (BP) in the convenience of their home. These instruments are touted as being accurate. METHODS: We conducted a study with volunteers who use BPMDs to see how they are used and to assess their accuracy. A BP reading was considered accurate if the differences between the volunteers' and technicians' systolic and diastolic readings were both 10 mm Hg or less. RESULTS: Of 91 patients, 31 (34%) obtained inaccurate readings. The inaccuracy could not be attributed to the type of the instrument, the cost of the instrument, the educational level of the user, or the age of the instrument. CONCLUSIONS: This study shows, despite other studies purporting accuracy, that a significant number of inaccurate readings are obtained by patients using BPMDs. Supervision of their use needs to be incorporated into the physician follow-up to ensure that there is a reasonable correlation between values obtained using the mercury sphygmomanometer and the BPMD.

Adult↗
PubMed1996

Tooth surface and pulp chamber temperatures developed during electrothermal bonding.

The rationale of electrothermal bonding is based on the premise that when an electric current is passed across the beaks of tweezers holding a stainless steel orthodontic bracket, heat will be generated by virtue of the electrical resistance of the steel bracket. This study was carried out to evaluate the temperatures generated on the tooth surface at the bracket/tooth interface and within the pulp chamber during electrothermal bonding. Temperatures were recorded with 5 and 7.5 A current levels applied as a 1 second pulse with time intervals between pulses of 1, 2, 3, and 4 seconds. The data showed that after three pulses with a 5 A current, the temperature on the tooth surface ranged between 43.3 degrees C (4 second intervals) to 53.6 degrees C (1 second intervals). By using a 7.5 A current, the temperature ranged from 77.5 degrees C (4 second intervals) to 85.9 degrees C (1 second intervals). The pulp chamber temperatures were evaluated in vitro for a mandibular incisor, the maxillary central and lateral incisors, a canine, a premolar, and a molar. The pulp chamber temperature of a mandibular incisor responded most, whereas that of premolars and molars responded least to temperature changes on the labial surface. The increase in mandibular incisor pulp chamber temperature after three pulses was 2.1 degrees C for 5 A and 2.8 degrees C for 7.5 A current while for a premolar the increase ranged from 0.9 degree C to 1.6 degrees C. On the basis of current evidence the increase in pulp chamber temperatures during electrothermal bonding may be considered to be clinically safe.

Bicuspid↗
PubMed1983

Racial patterns of alcoholic beverage use.

Among 59,766 persons who had routine health examinations in the years 1978 through 1980, the proportions reporting drinking among self-classified racial groups were: white, 89.5%; Latin, 84.8%; Japanese, 81.9%; black, 79.8%; Chinese, 68.1%; Filipino, 63.9%. Reported use of 3 or more drinks daily was similar in whites, Latins, and blacks but was much lower in the Asian groups. Men of all races reported more drinking than women. A large proportion of drinkers in all race-sex subgroups reported use of small amounts of alcohol, and most nondrinkers reported lifelong abstinence. Wine drinking (2+ days/week) was favored over spirits or beer by whites of both sexes and women of most races; beer use was favored by men of all races except white. All race-sex groups reported a strong alcohol-cigarette smoking association. Comparison with data collected 15 years earlier showed a substantial decline in reported proportions of abstainers and heavier (3+) drinkers as well as apparent narrowing of race-sex differences.

Adult↗