The main indication of thyroid hormone preparations is the treatment of hypothyroidism, ideally the goal of therapy is to restore the serum thyrotropin (TSH) concentration to a normal value. The optimal doses used to be stable, but several conditions may alter their requirements (reduced intestinal absorption, pregnancy,...). Levothyroxine therapy is also used in the benign nodular disease and after surgery in patients with thyroid cancer. The overtreatment with thyroxine and the problems related to bone mineral density seems of special importance.

Bone Resorption↗

PubMed1993

[Detection and management of lipid disorders in the diabetic patient].

Diabetics patients have a greater risk of morbi-mortality associated to macrovascular disease, which may show as ischemic cardiopathy, stroke and peripheric vascular disease. The high atherogenesis in these patients. Consequently, the therapeutical goals aimed to the reduction of plasmatic lipids must be stricter among the diabetic population and, especially, among women, that among non-diabetic subjects. The first therapeutical step should be to reach a proper metabolic control through diet, exercise and, if necessary, insulin or oral antidiabetics. If these measures are not enough, hypolipemic drugs should be added.

Cardiovascular Diseases↗