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Biomedical subjects

C Laurenti

Publications and source records attributed to C Laurenti.

At least 37 records · Page 2Linked to original sources
PubMed1984

[Medical treatment of cystine lithiasis in children].

Prophylactic measures or dissolution by medical therapy was used to treat bladder cystine stones in 14 children over about a 10-year period. All patients received alpha-MPG (alpha-mercaptopropionylglycine) except one child allergic to alpha-MPG who was treated with DNP (D-penicillamine). In 10 patients the treatment was administered 11 times to dissolve the stones, with resulting total dissolution in 6 cases, partial removal in one case. Two patients are still under treatment and 2 cases failed to respond. Among the 12 patients receiving preventive therapy, only 2 cases were reported as developing recurrences, due in fact to irregular taking of medication. Lytic treatment proceeded without any particular problems, and results were more than satisfactory, but for preventive therapy the difficulty resides in its application and duration when confronted with the serious and frequent danger of a relapse.

Amino Acids, Sulfur↗
PubMed1979

Ureteroureterostomy in complete ureteral duplication.

Homolateral pelvic ureteroureterostomies were performed in 25 patients presenting with complete duplication of the pyeloureteric tract. The procedure was performed in 16 cases of ureteroceles, in 7 cases of reflux in duplicated ureters, in 1 case of ectopic ureter and in 1 postoperative stenosis of one segment of a double ureter. According to the authors' experience this is the surgical treatment of choice in conservative surgical treatment.

Adult↗
PubMed1978

Renal carcinoma in a child.

A case of renal carcinoma in the left kidney of a 9-year-old female with parahilar lymph node metastases, surviving 9 years after surgery, is described. Referring to data in the literature, symptoms of infantile renal carcinoma, differential diagnosis, treatment and prognosis are discussed.

Adenocarcinoma↗
PubMed1975

Double bladder with complete sagittal septum: diagnosis and treatment.

A case of double bladder with complete sagittal septum in which the excluded bladder and septum were removed (together with the silent kidney and ureter) is described. Long-term follow-up has confirmed the success of the operation. Cases of this rare malformation reported in the literature are reviewed and diagnosis and therapy are discussed.

Child↗
PubMed1975

Development of the smooth muscle of the ureter and vesical trigone: histological investigation in human fetus.

The development of the muscular tissue of the ureter, ureterovesical junction and vesical trigone in the human fetus has been investigated using serial histological sections. The muscular tissue firstly appears in the lumbar tract of the ureter and the further smooth muscle development occurs in a cranio-caudal direction. The muscular tissue in the intravesical portion of the ureter is present only in fetuses between 22 and 24 weeks. The development of the muscular tissue of the trigone is dependent upon the development of smooth muscle of this tract.

Cell Differentiation↗
PubMedDate not supplied

Urothelial bladder carcinoma and viral infections: different association with human polyomaviruses and papillomaviruses.

Bladder cancer is the second most commonly occurring genitourinary cancer in adults. The interaction of different carcinogenic and cocarcinogenic agents are responsible for bladder urothelial carcinoma: alcohol and smoking habits, Schistosoma haematobium infection, exposition to chemicals, analgesic and antineoplastic drugs prolonged use. Recently also viral infections have been associated to this pathology. In this study the correlation between viral infections and bladder carcinoma has been evaluated. A group of 32 patients affected by primary bladder neoplasia has been analysed. A control group of 20 autoptic samples of healthy bladder was analysed. The DNA of the following viruses has been searched by polymerase chain reaction (PCR): Adenovirus, Herpes simplex virus type 1 (HSV-1), Herpes simplex virus type 2 (HSV-2), Human Papillomaviruses (HPV), Polyomaviruses (BKV and JCV). In the examined population the association bladder carcinoma-HPV, found by others, has not been confirmed. The high percentage of human polyomaviruses present in the samples is a statistically significant data (p=0.0087) and allows to presume that BKV and JCV may play a role in the aetiology of bladder tumor. In particular the polyomavirus BK, which is found in significative percentage both in single infection (p=0.0036) and in co-infections with other viral species (p=0.035), may be an important co-factor in the pathogenesis of bladder carcinoma.

Adult↗