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Biomedical subjects

C Lazăr

Publications and source records attributed to C Lazăr.

At least 19 recordsLinked to original sources

[Prevention and therapy of postoperative thyrotoxic crisis].

Out of a group of 361 patients with various anatomo-clinical forms of hyperthyroidia--of which 328 had underwent surgery--hospitalized in the Surgical Clinic from Jassy between 1965 and 1974, a total of 17 observations are analised, from the clinical and the therapeutical viewpoint, that showed postoperative thyreotoxicosis crisis. The fact is stressed that the prophylaxis of the crisis is dominated by the principle that no case of hyperthyroidia should be operated on before it has been perfectly balanced from the endocrinological viewpoint. The complex treatment of the cases that are presented included a symptomatic component to which were associated oxygen therapy, tonics, vitamins, hepatotrop preparations, eventually antibiotics. The results obtained--complete recovery in all the cases--can be compared with the best from the literature.

Adolescent

[Prognostic value of the chromosome pattern in tumors of the urinary bladder].

Cytodiagnostic and histopathological studies were made in 42 cases of epithelial urinary bladder tumours. The correlation was investigated between the modal chromosomal number, the frequency of the structural chromosomal aberrations and the degree of histologic malignancy (cellular anaplasy and invasion of the bladder wall). The proliferative rate was also determined of the analized tumours. In all the epithelial tumours that have been studied it was noted that the more malignant the tumour, the higher was the value of the modal chromosomal number, and the more frequent the chromosomal abnormalities. The proliferative rate of polyploid tumours was significantly higher as compared with that of the diploid ones. The presence of a polyploid mitotic population, as well as of structural chromosomal disturbances in a tumour with a low degree of malignancy, as demonstrated histologically, may have a prognostic significance.

Carcinoma

[Unusual localizations of hydatid cysts].

In a total of 448 hydatic cysts that have been treated in the I-st Surgery Clinic of Jassy between 1947 and 1977 rare localizations were noted in 61 cases. Of these 47 were primary echinococcoses and 14 were secondary. The clinical and therapeutic aspects are discussed for each particular localization: the splenic localization was encountered in 16 cases, the peritoneal one in 10 cases, the diaphragmatic in 6 cases. There were also 2 renal localizations, 3 retro-peritoneal ones, 3 ovarian and salpyngean localizations, 3 thyroid, 7 endo-thoracic but extra-pulmonary, 5 muscular and 6 subcutaneous localizations. Radical surgery had immediate and late results that were quite satisfactory. No deaths or recidives were noted.

Abdominal Muscles