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C León Gil

Publications and source records attributed to C León Gil.

12 recordsLinked to original sources
PubMed1997

[The role of meropenem in the treatment of pneumonia in the critical patient].

Pneumonia in critical ill patients, most of them associated with insaturation of an artificial a way and the use of mechanical ventilation, involves important morbi/mortality in the Intensive Care Units. Knowledge of pathogenesis, risk factors, and implicated microorganisms in developing of this major infectious complication, in the context of infections which rise in the critically ill patients, allow us to apply prophylaxis measures which could decrease its incidence, and establish antimicrobial therapy, which permit us to cover all the etiologic possibilities. Availability in the arsenal of the powerful antimicrobial, of a new carbapenemic, meropenem, and based on the different studies and clinic assays, allow to recommend its use with warranties and efficacy, in the empirical or's in concretely those due to Pseudomonas aeruginosa, enterobacteriaceae, (in general or producers of ample spectrum beta-lactamases), and Acinetobacter spp., in monotherapy or combined therapy, with aminoglycosides.

Clinical Protocols↗
PubMed1991

[Necrotizing infections of the soft tissues. Apropos of 40 cases].

The diagnosis of necrotizing soft tissue infection (NSTI) is based on a high suspicion index and/or clinical experience. Mortality is associated with delayed diagnosis and use of early surgical treatment, and also with the underlying disease and the patient's age. Usually they are mixed infections; therefore, in addition to surgical therapy an adequate antibiotic coverage is required. The latter, in cases of severe renal failure, might consist in monotherapy. All these guidelines can be modified on the basis of bacteriological findings. The Gram stain of a surgical sample can be very useful to select an appropriate empirical therapy. From a clinical point of view, we suggest to pay extreme attention to the findings consistent with NSTI: tenderness and/or crackling of soft tissue, rapid expansion through natural planes, or visualization of gas in the x-ray film of the involved zone, particularly if associated with a rapid deterioration of the general condition of the patient.

Adolescent↗