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Biomedical subjects

C Leboeuf-Yde

Publications and source records attributed to C Leboeuf-Yde.

At least 19 recordsLinked to original sources

Psychosocial factors at work in relation to low back pain and consequences of low back pain; a systematic, critical review of prospective cohort studies.

Relevant studies of low back pain (LBP) published between 1990 and 2002 were systematically retrieved via electronic databases and checking of reference lists. Forty papers fulfilled the inclusion criteria; 10 were of high quality. A wide variety of instruments had been used for collection of data on work related psychosocial factors, many of which had not undergone any form of validation. Moderate evidence was found for no association between LBP and perception of work, organisational aspects of work, and social support at work. There was insufficient evidence for a positive association between stress at work and LBP. No conclusions could be drawn regarding perception of work and consequences of LBP. There was strong evidence for no association between organisational aspects of work and moderate evidence for no association between social support at work and stress at work and consequences of LBP.

Cohort Studies↗

Ambiguous relation between physical workload and low back pain: a twin control study.

AIMS: To examine the association between self reported physical workload and low back pain (LBP) in younger twins. To investigate whether genetic factors interact with physical workload in relation to LBP. METHODS: A twin control study was performed within a population based twin register using 1910 complete monozygotic (MZ) and same sexed dizygotic (DZ) twin pairs aged 25-42 and discordant for LBP. LBP in the affected twins was divided into two groups: "LBP for </=30 days during the past year", and "LBP for >30 days during the past year". Physical workload was divided into four categories: "sitting", "sitting/walking", "light physical", and "heavy physical". Data were analysed in a matched design using conditional logistic regression. MZ and DZ twins were analysed separately and together in order to determine possible genetic influences in relation to physical workload and LBP. RESULTS: Statistically significant graded relations were found for increasing workload and LBP of longer duration but not for LBP of shorter duration (</=30 days during the past year). In both LBP groups the "sitting" and "sitting/walking" groups were not statistically different. MZ and DZ twins did not differ significantly with respect to LBP in the various workload groups. CONCLUSIONS: There is evidence for a dose-response relation between physical workload and LBP of longer duration. Attention to clinically relevant subgroups based on duration, for example, is necessary in epidemiological studies dealing with LBP. Physical workload might be more important than genetic factors in LBP.

Adult↗

Back pain reporting pattern in a Danish population-based sample of children and adolescents.

STUDY DESIGN: A cross-sectional survey of 806 pupils in Odense, Denmark was performed. This survey included children and adolescents ages 8 to 10 and 14 to 16 years obtained through two-stage cluster sampling from schools stratified according to school type, location, and socioeconomic character of the uptake area. OBJECTIVES: To establish the 1-month prevalence of neck, middle back, and low back pain and the consequences this disorder may have in relation to age and gender. SUMMARY OF BACKGROUND DATA: The differences in definitions of back pain and the variety of age groups included in previous studies make it difficult to draw clear conclusions about the onset of pain for various spinal regions in the young. METHODS: Information on back pain within the preceding month, obtained through a standardized interview of 481 children and 325 adolescents, was categorized according to area of pain, age, and gender. The consequences of back pain also were studied. RESULTS: The 1-month prevalence of back pain was 39%. Thoracic pain is most common in childhood, whereas thoracic pain and lumbar pain are equally common in adolescence. Neck pain and pain in more than one area of the spine are rare in both age groups. No gender differences were found. Of those who had back pain, 38% also reported some type of consequence, usually either visits to a medical physician or diminished physical activities. CONCLUSIONS: For clinical and research purposes, neck pain, middle back pain, and low back pain in childhood should be regarded as three specific entities. In future research the data for different age groups should be reported separately.

Adolescent↗

The association between physical workload and low back pain clouded by the "healthy worker" effect: population-based cross-sectional and 5-year prospective questionnaire study.

STUDY DESIGN: A population-based cross-sectional and 5-year prospective questionnaire study. OBJECTIVE: To investigate self-reported physical workload as a risk factor for low back pain. SUMMARY OF BACKGROUND DATA: Both physical and psychosocial workplace factors are considered risk factors for low back pain. However, today no consensus has been reached regarding the exact role of these factors in the genesis of low back pain. METHODS: Questionnaire data were collected at baseline for 1397 (and after 5 years for 1163) men and women aged 31--50 years at baseline. Low back pain ("any low back pain within the past year," "low back pain < or = 30 days in total during the past year," "low back pain > 30 days in total during the past year") was analyzed in relation to physical workload (sedentary, light physical, and heavy physical work) using logistic regression and controlling for age, gender, and social group. The proportions of workers changing between the workload groups over the 5-year period were analyzed in relation to low back pain status. RESULTS: At baseline no statistically significant differences in low back pain outcomes were found for workers exposed to sedentary, light physical, or heavy physical work. This was true for all age, gender, and social groups. At follow-up there was a statistically significant dose-response association between any low back pain and longstanding low back pain within the past year and increasing physical workload at baseline also after controlling for age, gender, and social group. Subjects with heavy physical workload at baseline changed statistically significantly more often to sedentary work if they experienced low back pain for more than 30 days out of the past year. CONCLUSIONS: Having a sedentary job might have a protective or neutral effect in relation to low back pain, whereas having a heavy physical job constitutes a significant risk factor. Because of migration between exposure groups (the "healthy-worker" effect), longitudinal studies are necessary for investigating the associations between physical workload and low back pain.

Cross-Sectional Studies↗

Prognostic values of physical examination findings in patients with chronic low back pain treated conservatively: a systematic literature review.

BACKGROUND: Most patients undergo physical examination. However, low back pain can only rarely be clearly diagnosed as having an irrefutable pathoanatomic cause on the basis of the classical battery of noninvasive physical examination procedures. However, physical examination findings are also used to predict the prognosis of treatment of chronic low back pain. A systematic review of the clinical literature is needed for an understanding of findings in this area. OBJECTIVES: To establish whether various physical examination procedures can be used to predict treatment outcome in the conservative (noninvasive) treatment of chronic low back pain. DATA SOURCES: From 910 titles published between 1986 and 1998, 10 original research reports were selected. These were obtained by means of a computerized MEDLINE search through use of various combinations of the key words low back pain, treatment, physical findings, predictors, prognosis, prognostic factors, prognostic indicators, and predictors and outcome(s); manual search strategies were also used. DATA SYNTHESIS: Articles that fitted the objectives of this review were retained and systematically reviewed for the prognostic value of the relevant tests/observations. In addition, results were studied in relation to type of outcome variable and type of treatment. RESULTS: The most commonly investigated tests were lumbar range-of-motion tests, which were found to have a clear-cut significant predictive value in 3 of 9 studies. Further analyses in relation to definition of outcome (back-to-work or reduction of symptoms) were not possible because study results were usually not clearly reported for each definition and because therapies were multimodal rather than distinctly well defined. CONCLUSIONS: This area has not been fully investigated. Therefore, there is no satisfactory answer to the question of whether some physical examination tests have a prognostic value in the conservative treatment of chronic low back pain.

Chronic Disease↗

Recovery pattern of patients treated with chiropractic spinal manipulative therapy for long-lasting or recurrent low back pain.

OBJECTIVE: To investigate the recovery pattern in chiropractic patients being treated for long-lasting or recurrent low back pain; in particular, to identify the minimum number of required treatments and the minimum number of days from the beginning of treatment to the occurrence of improvement. DESIGN: Prospective, uncontrolled multicenter study. SETTING: Private practice. PARTICIPANTS: Each of 19 selected Norwegian chiropractors provided 10 consecutive patients; each of the latter fulfilled a set of criteria (low back pain, a present episode longer than 2 weeks in duration, a total of more than 4 weeks of low back pain in the preceding year, no chiropractic treatment during the preceding 6 months, and suitability for manipulation). Response Rate: Data were collected on 164 patients (86% of the optimal study sample), 6 of whom were excluded. This left 158 patients for the analyses. MAIN OUTCOME MEASURES: Information on low back pain status was collected on each visit (maximum, 12 visits) through use of both a 10-point numeric pain rating scale and a global improvement scale (for the question "Do you feel that you have improved since you began receiving chiropractic treatment?," 5 answers were possible, ranging from "Yes, definite improvement" to "No, I am worse now than when the treatment started"). With respect to the numeric pain rating scale, "improvement" was defined as the point at which the score reached 2 for the first time or, if the initial score was 2, the point at which the score reached 1 for the first time. With respect to the global improvement scale, "improvement" was defined as the point at which the patient first answered "Yes, definite improvement." RESULTS: Approximately 50% of patients reported that they had "improved" at the 4th visit and within 2 weeks. After this time, fewer new cases of "improvement" occurred for every visit or day since the first treatment. At the 12th visit (earlier if treatment was concluded before the 12th visit), approximately 75% of the patients reported that "improvement" had occurred. CONCLUSION: There is a large group of chiropractic patients with relatively long-lasting or recurrent low back pain who report "improvement" early in the course of treatment.

Humans↗

Body weight and low back pain. A systematic literature review of 56 journal articles reporting on 65 epidemiologic studies.

STUDY DESIGN: A systematic review of the epidemiologic literature. OBJECTIVE: To establish if body weight is truly associated with low back pain (LBP) and whether the link may be causal. SUMMARY OF BACKGROUND DATA: Because obesity and LBP are prevalent in western society, it is of interest to establish whether obesity can induce LBP. METHODS: Fifty-six original research reports, reporting on 65 studies published between 1965 and 1997, were systematically reviewed for the frequency of positive associations between body weight and LBP. In addition, the presence of positive findings was examined in relation to several study characteristics. Based on these results, only studies emanating from the general population with a sample size exceeding 3000 were included in the additional search for causality using some of the classical Bradford-Hill criteria. The review was carried out by the author, blindly at 2 months' interval. RESULTS: Thirty-two percent of all the studies report a statistically significant positive weak association between body weight and LBP. Studies that fulfilled the post hoc criteria never report a rate ratio above 2, but there is possibly a positive biological gradient. These studies had no information on temporality or reversibility and there was no obvious consistency of findings. CONCLUSIONS: Due to lack of evidence, body weight should be considered a possible weak risk indicator, but there is insufficient data to assess if it is a true cause of LBP.

Body Weight↗

Whole-body vibration and low back pain: a systematic, critical review of the epidemiological literature 1992-1999.

OBJECTIVES: A previous extensive review of the literature including that from the middle of 1992 concluded that whole-body vibrations may contribute to low back pain, but that the exposure-response relationship had not been clarified. We reviewed the literature of the past 7 years to find out: (i) whether there is evidence in the recent epidemiological literature for a causal association between whole-body vibrations and low back pain, and (ii) if there is evidence in the recent literature for a dose-response relationship between whole-body vibrations and low back pain. METHODS: All relevant epidemiological articles which were obtained through a search in the databases MEDLINE, OSH-ROM and TOXLINE, and through personal communication, were reviewed independently by the two authors, using a checklist. RESULTS: Twenty-four original articles concerning the association between whole-body vibrations and the lower back were retained for use. The quality of the papers was mostly low, but improved with time. Only seven articles passed our predetermined quality criteria. Of the seven reports, one showed increased frequency of lumbar prolapse in occupational drivers, and six showed low back pain to be more frequent in whole-body vibration-exposed groups. Only two out of the four articles reporting on dose, showed a dose-response association. CONCLUSIONS: Despite the lack of definite evidence, we found sufficient reasons for the reduction of whole-body vibration-exposure to the lowest possible level. If new knowledge is to be produced, good prospective studies with repeated measurements of exposure, analyses of work postures, and clear definitions and subgroupings of low back pain are needed. Other research in this field should be given up, and the resources used for more important issues, as the size of the problem of whole body vibration is probably on the decrease because of the technical prophylactic developments that are already in progress.

Adult↗

Are chiropractic tests for the lumbo-pelvic spine reliable and valid? A systematic critical literature review.

OBJECTIVE: To systematically review the peer-reviewed literature about the reliability and validity of chiropractic tests used to determine the need for spinal manipulative therapy of the lumbo-pelvic spine, taking into account the quality of the studies. DATA SOURCES: The CHIROLARS database was searched for the years 1976 to 1995 with the following index terms: "chiropractic tests," "chiropractic adjusting technique," "motion palpation," "movement palpation," "leg length," "applied kinesiology," and "sacrooccipital technique." In addition, a manual search was performed at the libraries of the Nordic Institute of Chiropractic and Clinical Biomechanics, Odense, Denmark, and the Anglo-European College of Chiropractic, Bournemouth, United Kingdom. STUDY SELECTION: Studies pertaining to intraexaminer reliability, interexaminer reliability, and/or validity of chiropractic evaluation of the lumbo-pelvic spine were included. DATA EXTRACTION: Data quality were assessed independently by the two reviewers, with a quality score based on predefined methodologic criteria. Results of the studies were then evaluated in relation to quality. DATA SYNTHESIS: None of the tests studied had been sufficiently evaluated in relation to reliability and validity. Only tests for palpation for pain had consistently acceptable results. Motion palpation of the lumbar spine might be valid but showed poor reliability, whereas motion palpation of the sacroiliac joints seemed to be slightly reliable but was not shown to be valid. Measures of leg-length inequality seemed to correlate with radiographic measurements but consensus on method and interpretation is lacking. For the sacrooccipital technique, some evidence favors the validity of the arm-fossa test but the rest of the test regimen remains poorly documented. Documentation of applied kinesiology was not available. Palpation for muscle tension, palpation for misalignment, and visual inspection were either undocumented, unreliable, or not valid. CONCLUSION: The detection of the manipulative lesion in the lumbo-pelvic spine depends on valid and reliable tests. Because such tests have not been established, the presence of the manipulative lesion remains hypothetical. Great effort is needed to develop, establish, and enforce valid and reliable test procedures.

Chiropractic↗

Alcohol and low-back pain: a systematic literature review.

BACKGROUND: The role of lifestyle factors is an important issue in the prevention and treatment of disease. Although certain lifestyle factors in relation to low-back pain have evoked much interest, interest has not focused on alcohol consumption. An appraisal of the epidemiologic literature seems warranted. OBJECTIVES: To establish if there is evidence in the literature for a causal link between alcohol consumption and low-back pain. DATA SOURCES: Nine original research reports published between 1987 and 1995 were obtained through a MEDLINE search for the years 1992 to 1998, with various combinations of the terms "alcohol," "substance abuse," "life-style, " "risk factor," "epidemiology" and "low back pain." An additional manual search was made of relevant bibliographies without limitation for year of publication. DATA SYNTHESIS: A systematic review was made of the epidemiologic literature to uncover any evidence for a causal relation between alcohol consumption and low-back pain. RESULTS: None of the studies reported a positive link between alcohol consumption and low-back pain, and no positive gradient was found in studies that included an analysis of the dose-response. None of the studies was prospective in design. CONCLUSIONS: Alcohol consumption does not seem to be associated with low-back pain, but well-designed specific alcohol/low-back pain-centered studies are lacking.

Adult↗

Is sitting-while-at-work associated with low back pain? A systematic, critical literature review.

OBJECTIVES: To present a critical review and evaluate recent reports investigating sitting-while-at-work as a risk factor for low back pain (LBP). METHODS: The Medline, Embase and OSH-ROM databases were searched for articles dealing with sitting at work in relation to low back pain for the years 1985-97. The studies were divided into those dealing with sitting-while-working and those dealing with sedentary occupations. Each article was systematically abstracted for core items. The quality of each article was determined based on the representativeness of the study sample, the definition of LBP, and the statistical analysis. RESULTS: Thirty-five reports were identified, 14 dealing with sitting-while-working and 21 with sedentary occupations. Eight studies were found to have a representative sample, a clear definition of LBP and a clear statistical analysis. Regardless of quality, all but one of the studies failed to find a positive association between sitting-while-working and LBP. High quality studies found a marginally negative association for sitting compared to diverse workplace exposures, e.g. standing, driving, lifting bending, and compared to diverse occupations. One low quality study associated sitting in a poor posture with LBP. CONCLUSIONS: The extensive recent epidemiological literature does not support the popular opinion that sitting-while-at-work is associated with LBP.

Cohort Studies↗

Smoking and low back pain. A systematic literature review of 41 journal articles reporting 47 epidemiologic studies.

STUDY DESIGN: A systematic review of the epidemiologic literature on smoking and low back pain. OBJECTIVES: To establish whether smoking causes low back pain and whether cessation of smoking reduces the incidence and/or prevalence of low back pain. SUMMARY OF BACKGROUND DATA: It seems to have become increasingly commonly accepted that smoking causes low back pain and that abstinence from smoking is an effective means for its prevention and treatment. Does the evidence in the epidemiologic literature support this concept? METHODS: Forty-one original research reports reporting 47 studies, published between 1974 and 1996, were systematically reviewed for strength of association, dose-response correlation, temporality, reduction of symptoms with smoke cessation, and consistency of findings. In addition, the presence of positive findings was viewed in light of definition of low back pain, representativeness of the study sample, sample size, and in relation to whether the prime objective had been to study the smoking-low back pain issue. Two reviews were performed by the author, blindly and separated by a 2-month interval. RESULTS: There was no consistency of statistically significant positive associations between smoking and low back pain. The association, when present, was usually weak and clearly apparent only in large study samples. No other study characteristics had an effect on the frequency of positive associations. Additional analyses were therefore performed only on studies with large samples. In general, these did not contain consistent positive findings in relation to dose-response, temporality, or reversibility. Signs of causality were consistently evident only in the study with the largest sample (n > 30,000). CONCLUSIONS: Presently, smoking should be considered a weak risk indicator and not a cause of low back pain.

Humans↗

Low back pain and lifestyle. Part II--Obesity. Information from a population-based sample of 29,424 twin subjects.

STUDY DESIGN: A cross-sectional postal survey of 29,424 twin subjects aged 12-41 years obtained from a population-generated panel. OBJECTIVES: To determine whether obesity is associated with low back pain. SUMMARY OF BACKGROUND DATA: Despite a large number of epidemiologic studies in this area, it is unclear whether obesity and low back pain are positively associated, and if so, whether there is a causal association. METHODS: The association and dose-response connection between body mass index and nonspecific low back pain experienced by subjects in the preceding year were studied. Possible modifying effects of age, gender, type of work, and smoking were investigated. The prevalence of nonspecific low back pain was also studied in monozygotic twin pairs who were dissimilar in body mass index. RESULTS: There was a modest positive association between body mass index and low back pain that increased with the duration of low back pain. The underweight subjects consistently reported lower prevalence of low back pain (odds ratios < 1) than did those higher in weight. The dose-response curve was usually A-shaped. A positive monotonic dose response was apparent mainly in those with long-lasting or recurrent low back pain. The positive association between body mass index and low back pain disappeared when monozygotic twins who were dissimilar in body weight classification were studied. CONCLUSIONS: Obesity is modestly positively associated with low back pain, in particular with chronic or recurrent low back pain. However, because the association is weak, because there is no consistent positive monotonic dose response, and because the link disappears in monozygotic twins who are dissimilar in body mass index, it is unlikely that this association is causal. It is possible, however, that obesity plays a part in the chronicity of simple low back pain. Therefore, those with recurring or long-term low back pain deserve further attention.

Adolescent↗

Low back pain and lifestyle. Part I: Smoking. Information from a population-based sample of 29,424 twins.

STUDY DESIGN: A cross-sectional postal survey of 29,424 people aged 12-41 years obtained from a population-generated panel of twin individuals. OBJECTIVES: To study whether smoking causes low back pain. SUMMARY OF BACKGROUND DATA: Despite insufficient evidence in the epidemiologic literature, it has become increasingly accepted that smoking causes low back pain and that discontinuation of smoking is a suitable means of secondary prevention. METHODS: Dose-response was examined for smoking (daily use, number of years smoked, and total cigarette use during the years of smoking) in correlation with low back pain (occurring 1-7 days, 8-30 days, and > 30 days in the past year). A possible modifying effect was studied for age, gender, and body mass index. A negative gradient was sought in relation to the time since smoking was discontinued. The prevalence of low back pain was studied in monozygotic twin pairs, only one of whom smoked. RESULTS: There was a significant positive association between smoking and low back pain that increased with the duration of low back pain: occurring 1-7 days (odds ratio, 1.4), 8-30 days (odds ratio, 2.1), and more than 30 days (odds ratio, 3) in the past year. However, these differences in reports of low back pain disappeared in monozygotic twin pairs discordant on present smoke status. There was no biologic gradient for any of the low back pain definitions or measures of smoking-dose, and the prevalence of low back pain did not decrease with the number of years since smoking was stopped. Smaller people (youngsters, women, people with low body mass index) were not more vulnerable to development of low back pain with smoking. CONCLUSIONS: There is a definite link between smoking and low back pain that increases with the duration and frequency of the low back pain problem, but this link is unlikely to be causal.

Adolescent↗

[Whole body vibrations and low back pain].

Whether exposure to whole body vibration (WBV) in transport vehicles and moving machinery constitutes a health risk is unclear. The literature on this subject is vast, but most is of limited scientific value. A recent review covering the literature up to 1992 has been used as a basis for a further search concerning the period 1992-1996. Fifty-three articles were found: 14 epidemiological studies, 15 human laboratory experiments, four animal experiments, seven field studies and 13 reviews. Almost all epidemiological studies yielded insufficient information and had methodological shortcomings. Of the reviews, only three were critical. Experimental data support the hypothesis that WBV can have a negative effect on the spine. Epidemiological studies have shown drivers to have an increased prevalence of low back pain, probably in a dose-related fashion. Hence, it is likely that long-term exposure to WBV can contribute to back disorders. Present studies do not allow for a quantitative specification of the association between exposure and effect.

Animals↗

At what age does low back pain become a common problem? A study of 29,424 individuals aged 12-41 years.

STUDY DESIGN: A cross-sectional study was performed in a Danish population of individuals 12-41 years of age. OBJECTIVES: To study the lifetime cumulative incidence, the 1-year period prevalence, and point prevalence of low back pain in the general population and to investigate whether there were any differences in the occurrence of low back pain that were related to age and gender, especially in young individuals. SUMMARY OF BACKGROUND DATA: The epidemiologic literature fails to provide a credible estimate of the prevalence of low back pain in children and adolescents compared with that of adults. METHODS: A postal questionnaire was sent to 34,076 twins who were born between 1953 and 1982 and listed in the population-based Danish Twin register. The response rate was 86%. RESULTS: The prevalence of the various definitions of low back pain increased greatly in the early teen years (earlier for girls than for boys), and by the ages of 18 years (girls) and 20 years (boys) more than 50% had experienced at least one low back pain episode. The pattern for the 1-year period prevalence of low back pain was very similar to that for the lifetime prevalence; both started at 7% (95% confidence interval, 5-9%) for the 12-year-old individuals and reached 56% (95% confidence interval, 53-59%) and 67% (95% confidence interval, 62-71%), respectively, for the 41-year-old individuals. The pattern for the point prevalence resembled that of the more than 30 days of low back pain reported in the preceding year; the rate increased steadily from 1% (95% confidence interval, 0-2%) to 1.7% (95% confidence interval, 14-20%). There was a general tendency for more women to report low back pain than men, but this difference generally was not statistically significant. CONCLUSIONS: The study of the causes and prevention of low back pain needs to be focused on childhood and adolescence.

Adolescent↗