Role of hnRNP A1 in coronavirus RNA synthesis.
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Animals↗
Biomedical subjects
C Lyle
Publications and source records attributed to C Lyle.
Assessment of two hand hygiene regimens for intensive care unit personnel.
OBJECTIVE: To compare skin condition and skin microbiology among intensive care unit personnel using one of two randomly assigned hand hygiene regimens: a 2% chlorhexidine gluconate (CHG)-containing traditional antiseptic wash and a waterless handrub containing 61% ethanol with emollients (ALC). DESIGN: Prospective, randomized clinical trial. SETTING: Two critical care units (medical and surgical) in a large, metropolitan academic health center in Manhattan. SUBJECTS: Fifty staff members (physicians, nurses, housekeepers, respiratory therapists) working full time in the intensive care unit. INTERVENTIONS: One of two hand hygiene regimens randomly assigned for four consecutive weeks. MEASUREMENTS AND MAIN RESULTS: The two outcomes were skin condition (measured by two tools: Hand Skin Assessment form and Visual Skin Scaling form) and skin microbiology. Samples were obtained at baseline, on day 1, and at the end of wks 2 and 4. Participants in the ALC group had significant improvements in the Hand Skin Assessment scores at wk 4 (p = 0.04) and in Visual Skin Scaling scores at wks 3 (p = 0.01) and 4 (p = 0.0005). There were no significant differences in numbers of colony-forming units between participants in the CHG or ALC group at any time period. The ALC regimen required significantly less time than the CHG regimen (mean: 12.7 secs and 21.1 secs, respectively; p = 0.000) and resulted in a 50% reduction in material costs. CONCLUSIONS: Changes in hand hygiene practices in acute care settings from the traditional antiseptic wash to use of plain, mild soap and an alcohol-based product should be considered. Further research is needed to examine the association between use of antiseptic products for hand hygiene of staff and reductions in nosocomial infection rates among patients.
Adult↗
Developing the perfect long-term mattress.
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Beds↗
A third-year family medicine clerkship based in an academic family practice center.
In this paper, the authors describe the planning, curriculum, and evaluation of a five-week family medicine clinical clerkship for third-year students based in an academic family practice center. The program is an outpatient experience utilizing several innovative techniques: (a) problem-based learning that focuses on patient management tutorials, (b) consultation sessions with individuals offering specialized expertise, (c) supervised patient care in a family practice center and with a nursing home inpatient teaching service, and (d) workshops on various topics, such as office-surgical techniques, practice management, and alternative methods of health care. Evaluation of the course has demonstrated the merits of careful planning with student input, the need for flexibility, and the value of focusing on concepts in ambulatory care.
Academic Medical Centers↗
Prone positioning rocker for severely disabled persons.
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Child↗
The transscleral VER: normal responses.
Normative data taken on a sample of 10 eyes indicate that transscleral visual evoked response (TVER) stimulation of the cortical evoked response with a range of lights and at lower adaptation levels produces replicable, low-variance responses which may be of sufficient quality for the clinical evaluation of retinal and visual pathway condition. Response amplitudes were related to the radiant peak-power of white stimuli but were greater for red stimuli. Attenuation of the subjective brightness of the stimulus delivered through the inferior lid and sclera was about 0.4 log units compared to corneal delivery. Typical signal:noise ratios were 5:1.
Adolescent↗
An economic power spray.
A simple adaptation which can be made to enable a manually operated spray to be used and controlled with low-flow oxygen is described.
Anesthesia, Local↗
Assessing the impact of staff development on nursing practice.
The purpose of the study was to evaluate the influence of a geriatric nursing education workshop on nursing staff competency. Forty-three nurses participated in the study, which used an intervention and comparison group research design with pretest and posttest measures. The results indicated that participation in the workshop increased nurses' knowledge of gerontologic issues and improved nurses' ability to assess patients and to plan and document nursing interventions in patient charts. The intervention did not have a significant impact on collaborative practice, role ambiguity, or job satisfaction.
Clinical Competence↗