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C M Arroyave

Publications and source records attributed to C M Arroyave.

59 records · Page 4Linked to original sources
PubMedDate not supplied

[Klebsiella pneumoniae glycoproteins as coadjuvants in the prevention of recurrent respiratory infections in children 1-6 years of age].

MATERIAL AND METHOD: Forty two children with clinical diagnosis of recurrent high and low respiratory infections, were treated with an extract of P1 and F1 glycoproteins; fraction of Klebsiella pneumoniae, 1 g/day for one week a month for three months, according to a double-blind, randomized, parallel group trial. RESULTS: Improvement of clinical and laboratory results were compared with 44 control patients with the same age and similar sex distribution, that were treated with placebo. At the end of study, clinical analysis at 6, 9 and 12 months after the initial dose of Klebsiella pneumoniae, decreased in the number of respiratory infections, sick days, and school assistance were observed in the study group when compared with the control group (p < 0.001 in all parameters). There were not statistical significant changes in hemolytic complement, C3, C4 and immunoglobulins (IgA, IgG, IgM and IgE) levels before and after treatment and between groups. There were not observed adverse reactions to oral treatment with this extract of Klebsiella pneumoniae. CONCLUSIONS: These results suggested that the extract of Klebsiella can be used as a coadjuvant in the treatment of pediatric patients with recurrent high and low respiratory infections.

Adjuvants, Immunologic↗
PubMedDate not supplied

[Recurrent otitis media with effusion and food allergy in pediatric patients].

INTRODUCTION: Recurrent otitis media with effusion continues to be important pediatric clinical problem and is related to food allergy. OBJECTIVE: The purpose of the present investigation was to determine if the recurrent otitis media with effusion was associated to food allergy. METHODS: We reviewed medical charts from children with food allergy and otitis media with effusion for a period of three months of duration or every month for the last six months seen in an allergy clinic. Patients with anatomic abnormalities, polypous or immunologic deficiencies were excluded. Every patient was challenged with foods to which he/she was allergic in order to demonstrate cause-effect. In all patients we performed tympanometries. RESULTS: We found twenty five patients with recurrent otitis media with effusion and food allergy demonstrated by positive skin testing. The most common food found to be associated was milk, egg, beans, citrus, and tomato. The elimination of the food diet led to a significant amelioration of the otitis in 22 patients, in whom clinical and tympanometry evaluation was performed. The challenge diet with suspected offending food provoked a recurrence of the otitis problem. CONCLUSION: These results demonstrated the association between recurrent otitis media with effusion and food allergy. Therefore, all patients with recurrent otitis media with effusion should be investigated for food allergy.

Acoustic Impedance Tests↗
PubMedDate not supplied

[Identification of antinuclear, nucleolar and SS-A antibodies, using an immunoassay system].

In this paper we report a solid phase ELISA for screening of antinuclear, nucleolar, and SS-A antibodies. The test system was evaluated with 158 sera that were positive by immunofluorescence (IF), some of which were immunologically characterized as containing antibodies to Sm, RNP, SS-A, SS-B, nucleolar, and DNA, and 247 IF negative that were used as a control group. Ninety eight per cent of serum samples with an antibody of known specificity and/or positive IF, were positive by the ELISA system including antinucleolar samples. Reproducibility of the assay was demonstrated by using five sequentially prepared antigenic extracts. The lineal regression from the last experiment was between 0.75 and 0.91. With this system, positive and negative ANA can be identified as the screening procedure without the need of additional studies. To our knowledge this is the first ELISA system report for the screening of antinucleolar antibodies.

Antibodies, Antinuclear↗