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Biomedical subjects

C M Bosanko

Publications and source records attributed to C M Bosanko.

5 recordsLinked to original sources

CT in abdominal and pelvic trauma.

Computed tomography (CT) is valuable in the evaluation of the abdomen and pelvis in victims of blunt trauma and stab wounds to the back if their condition is stable or if results of their physical examination are unreliable (eg, due to altered mental status). The appearance of blood at CT depends on window width, hematocrit, physical state of blood, use of intravenous contrast material, and attenuation of adjacent organs. Rapid infusion of contrast material improves visualization of hematoma. CT is most useful in evaluating injuries to the spleen, liver, pancreas, kidney, duodenum, and small and large bowel. Although CT can be accurate in demonstrating lacerations and hematoma, radiologists must beware of pitfalls in the CT diagnosis of splenic injuries (normal lobulation or cleft within the spleen, elongation of the left hepatic lobe, adjacent unopacified bowel loop, previous splenic infarct), hepatic injuries (beam-hardening artifact from adjacent ribs, air-contrast level in the stomach), and pancreatic injuries (streak artifacts from nasogastric tubes, folding of the pancreas, misinterpretation of adjacent structures, pancreatic contusion or hematoma, intrinsic elasticity of the pancreas). Delayed scanning or scanning with slow infusion rates may also obscure hematoma. Knowledge of the various appearances of the posttraumatic abdomen and pelvis on CT scans is essential for prompt and effective treatment of patients.

Abdominal Injuries↗

Optical spectroscopy (INVOS) is unreliable in detecting breast cancer.

Recently a new nonionizing, nonimaging technique for evaluating risk of breast cancer, in vivo optical spectroscopy (INVOS), became available. The procedure evaluates the biochemical composition of the breast with spectrophotometry to provide a risk number related to the development of breast cancer. INVOS was evaluated in a prospective study of 180 women who were referred to our institution for needle localization and excisional biopsy of 181 breast lesions. All women had mammography and INVOS before surgical biopsy. The INVOS risk numbers and mammographic findings were compared with the pathologic diagnoses. Of 39 breast cancers, 19 (49%) had high-risk INVOS numbers, as did 52% of women with benign disease. INVOS had a sensitivity of 95%, specificity of 4%, and a positive predictive value of 21% for the detection of breast cancer. Mammography predicted malignancy with a sensitivity of 97%, specificity of 48%, and a positive predictive value of 34%. Receiver-operating-characteristic (ROC) curve analysis also was performed. The ROC area for mammography was 0.85 compared with 0.43 for INVOS, indicating a significantly greater (p less than .0000001) ability for mammography to detect breast cancer. We conclude that because INVOS cannot accurately predict the presence of breast cancer, it is unlikely that INVOS can be used to predict which patients are at risk for the development of breast cancer.

Adenofibroma↗

Lobar primary pulmonary lymphoma: CT findings.

A case of lobar primary pulmonary lymphoma is presented. In an asymptomatic patient with chronic lobar consolidation, CT confirmed the absence of a hilar mass or mediastinal adenopathy and demonstrated patent but stretched and irregularly narrowed bronchi.

Humans↗

Mixed cystic gliosarcoma and primitive neuroectodermal tumor: a case report.

The clinical and pathologic features of a mixed (composite) gliosarcoma and primitive neuroectodermal tumor occurring in a 54-year-old male are presented. A large cyst and the presence of Rosenthal fibers are also unusual features of this tumor. To our knowledge, such a morphologically variegated tumor has not previously been reported.

Brain Neoplasms↗