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Biomedical subjects

C M Cole

Publications and source records attributed to C M Cole.

18 recordsLinked to original sources
PubMed1992

Cholelithiasis associated with medroxyprogesterone acetate therapy in men.

Five out of forty-five adult men, 50 years of age or less, who had received, for at least six months, medroxyprogesterone acetate (MPA, Depo Provera) IM, 200-400 mg/week, for prevention of sex-offending or genital-mutilating behavior developed symptomatic cholelithiasis. Thirty of these men were studied with gallbladder ultrasound prospectively off MPA and at six-month intervals while taking the medication and then six months off MPA. Gallstones recovered from two patients were found to have very high cholesterol content, suggesting they were formed in cholesterol supersaturated bile. These findings are consistent with the increased incidence of gallbladder disease related to high-progesterone states and suggest that MPA may be a causative agent in cholelithiasis. The physiologic studies on gallbladder contraction and cholecystokinin release in a subset of the patients failed to provide information on a mechanism for the possible increased incidence of gallbladder disease.

Adult↗
PubMed1991

Anatomic variation of the corpus callosum in persons with gender dysphoria.

Previous postmortem anatomical studies have demonstrated differences between male and female in the size and shape of the splenium of the corpus callosum. The current study using the magnetic resonance imager compares the corpus callosum in 20 transsexuals and 40 controls to determine if the anatomic variance is related to anatomic sex or gender identity. No statistical differences were found in the cross-sectional areas of the entire corpus callosum, regardless of genetic sex or gender. However, the genetic males did have a larger whole-brain cross-sectional area. Also, even though there was a wide range of differences in shape and size in the splenium, the study found no significant differences between the sexes or between transsexual patients of either sex and the controls.

Adult↗
PubMed1991

Obstetric practice patterns among family practice residency graduates.

Obstetric services are a critical health care need in the southeastern United States. Until recently, many family physicians included obstetrics as a part of their practice. In recent years there has been significant attrition from the practice of obstetrics among family physicians. This survey looks at attrition among graduates of the Tuscaloosa Family Practice Residency Program and their practice patterns, as well as the reasons family physicians give for discontinuing obstetric practice. We also discuss implications for residency curricula and remedial measures at the state and national levels.

Alabama↗
PubMed1982

Observations on the influence of water and soil pH on the persistence of insecticides.

The pH-disappearance rate profiles were determined at ca. 25 degrees C for 24 insecticides at 4 or 5 pH values over the range 4.5 to 8.0 in sterile phosphate buffers prepared in water-ethanol (99:1 v/v). Half-lives measured at pH 8 were generally smaller than at lower pH values. Changes in half lives between pH 8.0 and 4.5 were largest (greater than 1000x) for the aryl carbamates, carbofuran and carbaryl, the oxime carbamate, oxamyl, and the organophosphorus insecticide, trichlorfon. In contrast, half lives of phorate, terbufos, heptachlor, fensulfothion and aldicarb were affected only slightly by pH changes. Under the experimental conditions described half lives at pH8 varied from 1-2 days for trichlorfon and oxamyl to greater than 1 year for fensulfothion and cypermethrin. Insecticide persistence on alumina (acid, neutral and basic), mineral soils amended with aluminum sulfate or calcium hydroxide to different pH values and four natural soils of different pH was examined. No correlation was observed between the measured pH of these solids and the rate of disappearance of selected insecticides applied to them. These observations demonstrate the difficulty of extrapolating the pH dependent disappearance behaviour observed in homogeneous solution to partially solid heterogeneous systems such as soil.

Half-Life↗
PubMed1981

The impact of sex therapy on sexual behaviors and marital communication.

The evaluation results of a short term intensive sex dysfunction workshop are presented. The evaluation research design involves before and after measures of sexual behaviors, sexual expectations, sexual communication, and marital communication. The results indicate that participants changed with regard to each of these variables. The workshop appears to impact couples in three ways: (1) there is a narrowing of the gap between actual and desired sexual behaviors, (2) there is improved sexual communication, and (3) there is improved marital communication. The results indicate that a combination of group instruction and individual therapy is an effective intervention technique in treating couples with sexual problems.

Adult↗
PubMed1981

A comparison of couples who have sought sex therapy with couples who have not.

The basic complaint of couples seeking sex therapy is that their sexual relationship is no longer satisfying to them, that they cannot deal with it. Although all couples who seek sex therapy feel that they have sex problems, not all couples experiencing sex problems seek sex therapy. We hypothesized that the way in which couples differ in their reaction to sex problems and their abilities to handle them is an important factor in determining their sexual satisfaction. To investigate this hypothesis, we looked at couples who attended a sex therapy clinic and at a demographically similar group of couples who have not sought sex therapy. The results suggest that factors in their relationship (marital functioning and communication and sexual communication) are a major difference between couples who seek therapy and those who do not.

Adult↗
PubMed1980

Participants' reactions to components of a rapid-treatment workshop for sexual dysfunction.

As part of a follow-up evaluation participants in a short-term rapid-treatment program for sexual dysfunction were asked to respond to items soliciting their reactions to program procedures and exercises. These questions were not designed as the sole evaluative instrument for the work, but rather as an additional attempt to explore an important process variable--participants' attitudes toward treatment. This article includes a description of the intervention procedures and summary tablets of participants' reactions. Findings suggest that attitudinal information collected directly from participants can be valuable in evaluating and modifying the therapeutic process.

Attitude↗
PubMed1979

The myth of symptomatic versus asymptomatic partners in the conjoint treatment of sexual dysfunction.

Although sex researchers and therapists alike talk about treating "couples," there persists an assumption that "symptomatic" partners vary significantly from "asymptomatic" partners with respect to early background and personality variables. Indeed, these differences have been sometimes viewed as primary causal factors for the couple's presenting state of sexual discord. Data from a short-term intensive treatment program was analyzed to compare factors such as parental-familial background, sexual attitudes and knowledge, and marital histories for individuals diagnosed as symptomatic and their partners who received no specific sexual diagnosis. Results indicated few significant differences between these identified groups. There were also few differences between groups based upon items from a follow-up evaluation, suggesting that the prognostic value of these classifications may likewise be placed in question. In general, the couple's ongoing relationship (rather than individual characteristics) appears responsible for establishing satisfactory levels of sexual intimacy. Suggestions were made toward developing couple-oriented diagnostic and outcome categories.

Adult↗
PubMedDate not supplied

Brief sexual counseling during cardiac rehabilitation.

Advances in the understanding and treatment of myocardial infarction have appeared over the past decade. One intervention technique receiving increasing emphasis is the development of multidisciplinary "rehabilitation teams" whose chief aim is to assist individuals in returning to former levels of medical and psychosocial functioning. Within the team approach, the mental health specialist clearly plays a significant role. Counselors can provide support and reassurance in the midst of the medical crisis and help to minimize stress related to rearrangements in family roles and routines. In this instance, brief sex counseling as part of an ongoing rehabilitation program serves to clarify misconceptions, reduce fears, and facilitate return to sexual activities after infarction. It is important to remember, however, that an accurate physiologic evaluation provides the foundation on which to base counseling efforts. Without adequate medical information, no amount of counseling expertise will succeed. Certainly the final decision to resume sexual behavior remains with the individual couple. The counselor's primary task is to emphasize that the myth of total abstinence is not applicable for most cardiac patients. In reality, it is possible and even highly beneficial for patient and spouse to return to their normal sexual relationship.

Counseling↗