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Biomedical subjects

C M Fisher

Publications and source records attributed to C M Fisher.

At least 127 records · Page 7Linked to original sources

Embolic occlusion of the superior and inferior divisions of the middle cerebral artery with angiographic-clinical correlation.

Clinicians, in defining cerebral vascular syndromes, recognize embolism to the superior and inferior divisions of the middle cerebral artery in addition to embolism of the individual branches. In the present study 14 examples of arteriographically visualized divisional occlusion are analyzed, and a good correlation is demonstrated between the roentgenologic and clinical findings.

Cerebral Angiography↗

Acute cerebellar infarction in the PICA territory.

Although old or recent infarcts of a cerebellar hemisphere in the territories of the posterior inferior (PICA), superior, or anterior inferior cerebellar arteries are commonplace autopsy findings, in no case have corresponding clinical symptoms been clearly identified. We have studied three cases, two clinocaopthologically and one clinicosurgically, in which an acute infarct involving only the cerebellum lay in the PICA territory distal to the branches to the medulla oblongata. The clinical manifestations consisted of rotatory dizziness intensified by motion, nausea, vomiting, imbalance, and nystagmus. In two cases, the clinical diagnosis had been a benign labyrinthine disorder. Recognition of a syndrome corresponding to cerebellar infarction in the PICA territory is important insofar as it assists in the differential diagnosis of dizziness. It becomes of crucial importance when cerebellar infarction is the prelude to cerebellar swelling and brain stem conpression leading to coma and death unless surgically relieved.

Acute Disease↗

Surgical treatment of extracranial carotid occlusive disease.

This report has reviewed the preoperative evaluation, operative technique, postoperative care, results, and representative pathological findings in 225 carotid endarterectomies. Surgery is generally indicated in patients with: 1. TIA's, and carotid stenosis (lumen diameter less than 2 mm.) or an ulcerated plaque. 2. A stable, mild to moderate neurological deficit with or without TIA's, and carotid stenosis (lumen diameter less than 2 mm.) or an ulcerated plaque. 3. An acute progressive or fluctuating neurological deficit, and carotid stenosis (lumen diameter less than 2 mm.) or carotid occlusion. Surgery should be considered in some patients with: 1. TIA's, and ipsilateral carotid occlusion. 2. An acute partial persistent neurological deficit, and carotid stenosis (lumen diameter less than 2 mm.) or occlusion. 3. No symptoms, and carotid stenosis (lumen diameter less than 2 mm.). Surgery is generally not indicated in patients with an acute severe persistent neurological deficit, and carotid stenosis or occlusion.

Aged↗

Stroke in a 15-year-old girl secondary to terminal carotid dissection.

A 15-year-old girl died 14 days after hemiplegia suddenly developed. On arteriography, intimal separation of the middle cerebral arteries showed as a long attenuated column of dye--the "string" sign. Pathologic examination showed intimal separation starting at the distal bifurcation of the right internal carotid artery and extending into the middle and anterior cerebral arteries. The arteriographic string sign as evidence of dissection may aid diagnosis of this cause of childhood hemiplegia.

Adolescent↗

Cerebral miliary aneurysms in hypertension.

The types of miliary cerebral aneurysms associated with hypertension were studied, using serial sections of blocks of brain tissue from hypertensive patients with a history of cerebral hemorrhage or lacunar infarcts or both. Four different structures were identified-three aneurysmal (saccular, lipohyalinotic and asymmetric fusiform) and one nonaneurysmal, the so-called bleeding globe. They probably account for all of the miliary cerebral aneurysms described during the past 100 years. The present survey is one of the most comprehensive yet undertaken.

Cerebral Arteries↗