Biomedical subjects
Publications and source records attributed to C M Lynne.
We report our experience with 18 consecutive cases of priapism treated with intracorporeal irrigations of dilute epinephrine solution. Of the 18 patients 16 were treated successfully. The 2 failures had priapism 36 hours and 5 days in duration, respectively.
A 29-year-old woman suffered a vesicouterine fistula following cesarean section. The fistula was treated successfully after cystoscopic identification and fulguration of the tract. Although various surgical approaches to this problem have been described, and a number of cases of spontaneous resolution are reported, to date there have been no reports of treatment of this problem via cystoscopic fulguration. We advocate this simple technique as a primary approach to vesicouterine fistulas.
Presented is a case of a bladder polyp diagnosed by ultrasound and removed by transurethral resection.
A patient with tuberous sclerosis presented with renal failure secondary to bilateral angiomyolipoma. The angiomyolipoma was associated with polycystic disease and a foci of renal cell carcinoma. This unusual combination has not been reported previously, although each entity has been described separately in tuberous sclerosis.
A case of fatal disseminated mucormycosis causing bilateral renal artery thrombosis, parenchymal and collecting system invasion and destruction, and extrinsic perirenal and proximal ureteral compression is presented. In addition to acute renal failure meningoencephalitis, cerebral hemorrhagic infarction and septic enterocolitis were contributing causes of death.
Twenty-four beagles received 4-aminobiphenyl orally 5 days a week for 3 years. The dogs were examined cytoscopically at frequent intervals. Biopsy and surgery were performed according to predetermined criteria. Three basic patterns of carcinogen responses were seen. Negative or minimal disease was seen in four dogs. Of these, two remained completely free of neoplasia. Eleven dogs progressed slowly in their development of neoplasia with minor fluctuations in development. A rapidly progressive pattern was observed in the remaining nine dogs. A large variance in the time of onset of the first positive diagnosis of neoplasia was seen. Eleven dogs underwent surgery ranging from tumor sampling to cystectomy plus ureterosigmoidostomy. Histologic types and grades and patterns of metastasis as well as several other characteristics seemed to parallel closely human bladder cancer.
A right flank mass, in a patient with fever of unknown origin, pain, and superiorly displaced right kidney on excretory urogram, was explored through a subcostal incision. Finding of a retroperitoneal abscess was anticipated; instead of a ruptured mycotic aortic aneurysm was encountered. An awareness that entities such as this may exist is imperative in the differential diagnosis of flank masses. Treatment through a flank incision presents an elusive if not impossible feat. Because of the gravity of the underlying disease, misdiagnosis almost always results in death.
Four of 8 cases that represent unusual and infrequent complications of the transvesicle Politano-Leadbetter ureteral reimplantation technique are reported. Approximately 90 per cent of ureteral reimplantations for vesicoureteral reflux may be done satisfactorily as a transvesical procedure but combining it with an extravesical approach of the ureter when necessary or indicated will serve to correct any conceivable congenital, acquired or iatrogenic lesion of the lower ureteral segment. The extravesical approach should be used if there is any difficulty in performing the procedure transvesically or if the patient has undergone previous attempts at antireflux operation. Obstructive complications may occur in either the early or late postoperative period. When discovered, surgical correction is usually indicated. We strongly advocate strict adherence to the surgical technique involved and meticulous postoperative followup of these patients.
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Spontaneous rupture of the kidney occurs rarely. Among the known causes polyarteritis nodosa is uncommon with less than 50 cases reported. Diagnosis is difficult to make with certainty. Our case concerns a 38-year-old man whose symptoms originally simulated acute renal colic. Nephrectomy was done. A brief review of the pertinent literature, diagnosis and management is presented.
The immunologic status of dogs undergoing bladder carcinogenesis with 4-amino-biphenyl and normal littermate controls is being evaluated. Studies using blastogenic transformation, nonimmune cytotoxic reactions, and rosette formation have revealed that dogs possess lymphocytes that have some properties similar to those of B and T cells of other species. Since tumors are now just appearing and hence are not yet available for specific immunologic determinations, the assessments had to be limited for the present to other types of antigens and mitogens (yeast, red blood cells and plant lectins). No major changes in reactions of cells from the carcinogenized animals have yet been observed during the preneoplastic phase as measured by phagocytosis, migration inhibition, or cytotoxicity tests, although a trend to lower blastogenic responses was noted. It yet remains to be seen whether lower lymphocyte responses to mitogens in carcinogenized dogs are of prognostic value for the early detection of tumors of the bladder.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.