Biomedical subjects
C M Reading
Publications and source records attributed to C M Reading.
Multiple sclerosis : is it transplacentally induced?
The aetiology of multiple sclerosis MS is not known. Most research workers believe a viral aetiology. An alternate theory - namely transplacental induction of MS is outlined. Correlative evidence is drawn from epidemiological studies, models of transplacentally induced conditions, metabolic disturbances in utero that can affect myelin development or result in offspring with defective immunological competence and surveillance. The relationship between B group vitamin deficiencies and mineral deficiencies and MS is considered. Primary, secondary and tertiary prevention of MS in view of this theory is outlined.
Effect of dieldrin and calcium on the performance of adult Japanese quail (Coturnix coturnix japonica).
Two experiments were conducted to determine the effects of dieldrin and calcium on reproductive performance of quail. At 25% egg production the quail received diets containing 0,10 or 25 p.p.m. of dieldrin for 6, 28-day periods in experiment 1 and 0, 5, or 25 p.p.m. of dieldrin for 4, 28-day periods in experiment 2. Pesticide treatments were employed with diets containing 0.5% and 3.0% calcium. The results show that egg shell thickness, cracked eggs, egg production, feed consumption, egg weights, fertility, hatchability and body weights were not affected by dieldrin treatments. However, egg shell thickness, cracked eggs, egg production and hatchability were adversely affected by the lower calcium level. Female body weights were consistently heavier for the low calcium diet. Mortality increased in the presence of 10 and especially 25 p.p.m. of dieldrin. Livability of chicks from hens receiving rations with 10 and 25 p.p.m. of dieldrin was significantly lower than those fed no dieldrin. In summary, dieldrin was without effect on egg shell quality or other reproductive factors but did exert a detrimental effect on adult mortality and livability of progeny.
Latent pernicious anaemia: a preliminary report.
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