Effect of mass media campaign to reduce socioeconomic differences in women's awareness and behaviour concerning use of folic acid: cross sectional study.
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Awareness↗
Biomedical subjects
C M de Rover
Publications and source records attributed to C M de Rover.
Periconceptional folic acid in The Netherlands in 1995. Socioeconomic differences.
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Educational Status↗
Risk of otitis externa after swimming in recreational fresh water lakes containing Pseudomonas aeruginosa.
OBJECTIVE: To determine whether an outbreak of otitis externa was due to bathing in recreational fresh water lakes and to establish whether the outbreak was caused by Pseudomonas aeruginosa in the water. DESIGN: Matched case-control study. SETTING: The Achterhoek area, the Netherlands. SUBJECTS: 98 cases with otitis externa and 149 controls matched for age, sex, and place of residence. MAIN OUTCOME MEASURES: Odds ratios for type of swimming water and frequency of swimming; presence of P aeruginosa in ear swabs and fresh water lakes. RESULTS: Otitis externa was strongly associated with swimming in recreational fresh water lakes in the previous two weeks (odds ratio 15.5 (95% confidence interval) 4.9 to 49.2) compared with non-swimming). The risk increased with the number of days of swimming, and subjects with recurrent ear disease had a greatly increased risk. The lakes met the Dutch bathing water standards and those set by the European Commission for faecal pollution in the summer of 1994, but P aeruginosa was isolated from all of them, as well as from the ear swabs of 78 (83%) of the cases and 3 (4%) of the controls. CONCLUSIONS: Even when current bathing water standards are met, swimming can be associated with a substantial risk of otitis externa because of exposure to P aeruginosa. People with recurrent ear disease should take special care when swimming in waters containing P aeruginosa.
Adult↗
Differences in individual responsiveness of serum cholesterol to fat-modified diets in man.
In the period 1963-1974, 82 monks and 48 nuns from five Dutch and Belgian Trappist monasteries each participated in two or more out of nine different trials designed to test the effect of 58 different fat-modified diets on serum cholesterol. We analysed these data to quantify the extent to which healthy, normolipaemic subjects differ in the responsiveness of their serum cholesterol to a change in dietary fatty acid composition. Statistically significant between-person variance components (SD2p) were found in the serum cholesterol responses for the whole group (SD2p = [0.20 mmol l-1]2), for the men (SD2p = [0.24 mmol l-1]2) and for those women who participated in three or more trials (SD2p = [0.14 mmol l-1]2). The between-person variation (expressed as SD) was on average only half as large as the within-person variation in response when the same subject was challenged repeatedly. It is concluded that medically significant differences in responsiveness to fat-modified diets exist in both men and women. However, few subjects fail entirely to respond to a change in dietary fatty acid composition. In addition, the large within-subject variability makes it difficult to identify hypo- and hyperresponders.
Adult↗
Urinary porphyrin pattern in liver damage.
Known techniques were used with slight modification to analyse and quantify porphyrins in the urine samples of normal human subjects, of clinically established jaundice cases and of women taking oral contraceptives. The results indicate that the urinary porphyrin pattern can be a useful tool in the detection of early liver injury.
Adult↗