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Biomedical subjects

C Maestrone

Publications and source records attributed to C Maestrone.

5 recordsLinked to original sources

[Benzodiazepine and flumazenil in elective electric cardioversion].

The Authors report on the use of Flumazenil (Antagonist of the benzodiazepines in the CNS) in patients awakening from benzodiazepine induced necrosis for defibrillation. When used in these circumstances, the normal side effects of the narcosis (arrhythmia, rebound hypertensive convulsions, states of paradoxical anxiety) were almost completely absent. Furthermore, given the optimal quality of the rapid awakening, in about 5 minutes, the antagonistic qualities of the drug were confirmed making further development of the therapeutic uses of the benzodiazepines possible.

Adult↗

[Transportation during the night with the military anesthesia and resuscitation service: importance in urgent transfers].

The A.A. show a clinic case of a 37 years old person injured by a thunder due to a contact with high intensity electric energy, with a lot of scalds of first, second and third degree, on 70% of the body surface, in which there was necessity of Air-Force to bring the person out of the Region border, and out of the working time of the Regional helicopter assistance. The A.A. want you to know the importance of S.A.R. in particular weather situations and places that are not contemplated by Regional helicopter assistance lous.

Adult↗

[Urapidil in intraoperative continuous infusion].

The author reports the results of a clinical experiment with Urapidil administered in continue infusion to induce controlled hypotension during hemilaminectomies. The reduction of pressure values is obtained after 15-20 minutes since the beginning of drug infusion (35-40% compared with the starting basis values); moreover, because of the double action mechanism of the drug (central and peripheral), "reflex tachycardia", a common symptom in hypotensive drugs used in the past, disappears. In addition, the author states that the absence of potentially toxic degrading metabolites and the lack of "rebound" hypertensive phenomena or tachyphylaxia assure very good administration and pharmacological security of the drug.

Adult↗