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Biomedical subjects

C Mangano

Publications and source records attributed to C Mangano.

14 recordsLinked to original sources

Interface between hydroxyapatite and mandibular human bone tissue.

Samples from intraosseous dental implants, removed from patients for mechanical failures, were examined to analyse the interaction between hydroxyapatite as plasma sprayed coating on titanium supports and human bone. The implantation time varied up to 8 years. No failures had arisen from problems at the interface between the hydroxyapatite coating and bone. The number of samples examined and the implantation times give good statistical conclusions. Histological and microchemical studies showed the good performance and compatibility of this sprayed hydroxyapatite. We present evidence from the best samples which show close bonding with the surrounding bone tissue. New bone is seen all around the coated implant. The composition of the calcium phosphate deposited on the hydroxyapatite and cellular approach were determined, and demonstrate the efficiency of the interaction between this plasma sprayed hydroxyapatite and the bone.

Adhesiveness

[Clinico-epidemiologic considerations in cases of acute viral non-A, non-B hepatitis (NANB)].

Personal experience with a series of 69 cases of non-A, non-B viral hepatitis out of 164 cases of acute viral hepatitis observed at hospital admission between January 1985 and June 1988 is reported. Agreement is expressed with other Italian series as regards the incidence of sex, of the most involved age classes, of the most affected professional categories and of the incubation period of posttransfusional forms. The prevalence of sporadic forms over those transmitted intraparenterally and more prolonged course in icterus patients and in parenteral forms is pointed out.

Acute Disease

[Granular CHA in oral surgery. Clinical and therapeutic aspects].

The Authors report their experience and the clinical results obtained by the use of powders of calcium-hidroxylapatite (Dac Blu) as filling material for bone defects in many different cases. The positive biological response justifies a wider utilisation of this material in oral surgery.

Bone Resorption

Ventricle morphology in pelagic elasmobranch fishes.

Ventricle weights of the warm-bodied great white shark, Atlantic shortfin mako, and the common thresher shark (the latter presumed to be warm-bodied) are similar to those of ectothermic blue sharks, sandbar sharks, dusky sharks, tiger sharks and scalloped hammerhead sharks. Ventricle muscularity, as estimated by the ratio of cortical to spongy layer thickness, is almost twice as great in the former three species than in the latter elasmobranchs. Measurements of ventricular volumes suggest that the ventricles of the great white, Atlantic shortfin mako and common thresher sharks are better adapted to respond to demands for increases in cardiac output via increased heartbeat frequency in comparison with ectothermic species of shark.

Animals

Preparation-induced stability of bioactive apatite coatings.

The stability of the bioactive surface is a major concern in the chemical and physical design of apatite ceramic coatings. In clinical studies, no sintered-hydroxyapatite bulk coating material was present in the surrounding bone tissue after loading periods up to 11 years. In in vitro studies, hydroxyapatite plasma-sprayed coatings dissolved considerably, possibly because of loss of crystallinity during the plasma-spraying procedure. A heat treatment at 600 degrees C reconstituted the crystallinity and promoted the transformation of alpha-tricalcium phosphate into the more stable beta-tricalcium phosphate. Fluorapatite coatings did not lose their crystallinity and had the added advantage of stability as a result of the fluoride ion.

Animals