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Biomedical subjects

C Mascrès

Publications and source records attributed to C Mascrès.

9 recordsLinked to original sources
PubMed1979

[Ultrastructure of the buccal mucosa in the non-smoking cirrhotic patient].

Ultrastructural analysis of biopsies of the buccal mucosa was carried out in 12 non-smoking patients and 10 smokers with a confirmed clinical diagnosis of alcoholic cirrhosis. Certain signs of epithelial dysplasia, including increase in nuclear cytoplasmic ratio, proeminence of the nucleolus, fragmentation and proliferations of the basal layer accompanied or not by epithelial projections into the chorion, were seen in non-smoking cirrhotics, as in the smokers. These findings emphasise the predominant role of alcohol alone in carcinogenesis.

Adult↗
PubMed1978

Allergies of the dental pulp.

A review of publications relating to the allergies of the dental pulp is presented. The pulp--especially when inflamed--contains antigens, lymphocytes, plasmocytes, IgG, IgM, IgA, and IgE antibodies, mast cells, histamine, and possibly C3. However, no antibody-mediated allergy (hypersensitivity) of the pulp has yet been demonstrated. On the other hand, two types of cell-mediated allergy--the graft-rejection reaction and contact hypersensitivity--have been reported, as well as autoimmunity.

Animals↗
PubMed1978

[Allergies and dental pulp (author's transl)].

A review of the articles dealing with allergy in the dental pulp is oppered. The dental pulp--furthermore when inflamed--showes antigens, lymphocyetes and plasmocytes, antibodies (IgG, IgA and IgE), mast-cells, histamine and possibly C3. However an hypersensitivity or allergy of immediate type elicited by circulating antibodies has never been demonstrated. In another way, two types of allergies of cellular type have been described in the dental pulp: graft rejection and contact hypersensitivity. Autoimmunity has also just been described.

Animals↗
PubMed1977

[Induction of autoallergic pulpitis in rabbit (author's transl)].

Six male rabbits were injected on days 0, 6 and 12, subcutaneously, intraperitoneally and subcutaneously with 0.5 ml/kg of a 20% suspension of homologous dental pulp, in complete Freund's adjuvant. Six controls received complete Freund's adjuvant only. Leukocytes were counted regularly. A skin test was performed on day 18. On day 22, a dental test was performed to study the macrophage migration inhibition "in vivo". On day 23, the animals were killed, the teeth and skin were analysed histologically. The following results were observed in the experimental group: 1) inhibition of growth, 2) leukocytosis and eosinophilia, 3) a positive skin test with a strong lymphocytic infiltration, 4) an inhibition of "macrophage migration", 5) pulpal lesions, numbering 1 to 6 per rabbit, with lymphocytic plasmocytic and eosinophilic perivascular infiltration. These results indicate an experimental auto-allergic pulpitis. The mechanisms of human pulpitis ought to be reexamined in the light of these observations.

Animals↗
PubMed1975

[Changes in the muscle fiber induced by p-phenylenediamine in the rat].

P-phenylenediamine (PPD) induces skeletal muscle lesions in rats which have been chosen as a model for investigation of the inflammatory and degenerative pattern of the muscle fibers. With the use of histochemical and ultrastructural criteria, the morphology of the lesions have been analysed in the diaphragm. Fifteen minutes after the induction by PPD, a subsarclemmal oedema can be shown by electron microscopy. Enzymatic changes appear during the first hour. The pathologic features are more prominent after twenty-four hours. The lesions are characterized by a segmental necrosis adjacent to unaltered fibers and by particular types of fibers such as target, snake coils, core fiber. A comparison between the lesions induced by PPD and those occurring during other types of myopathies has been made.

Adenosine Triphosphatases↗