Biomedical subjects

C Massias

Publications and source records attributed to C Massias.

3 recordsLinked to original sources

PubMed2000

[Fetal alcohol syndrome].

Fetal alcohol syndrome is frequently observed. It is estimated that 0.2% of newborns in France have fetal alcohol syndrome, a rate which reaches 1% in certain studies. Ultrasound diagnosis is straightforward, based on: - intrauterine growth retardation, predominantly involving the limbs and occurring early without oligoamnios; - specific facial dysmorphism with two essential signs, frontal rounding of the philtrum, suppression of the Cupidon arch; - several malformations involving the corpus callosum, ocular and renal tissue; - markedly higher incidence in multiple parity women over thirty who gain little weight during pregnancy. We report seven cases observed between 1994 and 1999 and discuss the growth curve and the facial dysmorphism.

Adult↗

PubMed1994

[Recurrence of common truncus arteriosus. Prenatal diagnosis of a case report].

We report a case of isolated truncus arteriosis diagnosed prenatally which recurred during a subsequent pregnancy. This observation would suggest an increased risk of recurrent single trunk malformation as compared with other congenital heart diseases, in agreement with our understanding of the genetic processes involved. A prenatal screening can be achieved with a systematic examination of the fetal morphology. Prognosis is severe and prenatal diagnosis is difficult.

Abortion, Therapeutic↗

PubMed1989

[Tracheal agenesis].

A case of tracheal agenesis is reported. At present, this lethal and rare malformation cannot be recognized before birth. Circumstances of the pregnancy and the stages leading to the diagnosis at birth are reported. Autopsy allows to classify the type of malformation and to search for others malformations, as seen in the VATER syndrome. A tracheo-oesophageal fistula is always present. The mechanism is unknown and there is no chromosomal anomaly. Fifty cases have been published in literature.

Humans↗