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Biomedical subjects

C Mayor

Publications and source records attributed to C Mayor.

17 recordsLinked to original sources
PubMed1992

[Complementary information from Doppler echocardiography in the electrocardiogram in the basic assessment of chronic coronary heart disease, especially following a myocardial infarct. Observations from an ambulatory cardiology clinic].

In chronic ischemic heart disease, Doppler echocardiography (DE) at rest permits semiquantitative evaluation of scarring and remodelling processes, global ventricular function and, frequently, regional wall motion state. Late complications are detected, namely infarct expansion, true and false ventricular aneurysm, mitral insufficiency, thrombus formation, and associated valvular and aortic diseases are discovered. We studied 100 patients with known chronic coronary artery disease referred for noninvasive evaluation, including electrocardiogram (ECG) and DE. In all patients, the global left-ventricular function was satisfactorily assessable. In roughly two thirds of the documented infarctions. DE confirmed the ECG diagnosis and permitted a more precise diagnosis in the majority of them in terms of localization and/or dimension of the necrosis. In one third of the patients. DE clarified inconclusive ECG tracings. Thus, the baseline noninvasive investigation with ECG and DE is a potent tool in the management of chronic ischemic heart disease, serving as a guide to further investigation and to treatment adjustments.

Adult↗
PubMed1992

Risk for definite neuroleptic malignant syndrome. A prospective study in 223 consecutive in-patients.

The occurrence of neuroleptic malignant syndrome (NMS) was studied prospectively in two series of consecutive psychiatric in-patients (n = 223). The first group (n = 120) suffered from schizophrenia and was treated only with haloperidol. The second group (n = 103) was treated with diverse neuroleptics. All patients were on a single antipsychotic agent with no anticholinergic drug as prophylaxis. The incidence of full NMS per admission and first neuroleptic exposure was 5/223 (2.2%). Patients with bipolar affective disorder and those treated with injections were significantly over-represented in the NMS group.

Administration, Oral↗
PubMed1989

[The value of color Doppler studies to conventional cardiac Doppler studies].

Colour Doppler is a recent and important development among non-invasive diagnostic techniques in cardiology. A series of 500 adults has been studied in order to define the contribution made by colour Doppler to conventional Doppler. After elimination of patients with normal echo Doppler studies, colour Doppler contribution has been considered useful in 51% of the cases and was essential in 13%. Main contributions have been noted in valvular regurgitations, multiple valvular lesions, prosthetic valves and congenital cardiopathies. Colour Doppler appears as an useful, but not as an indispensable complement to conventional Doppler in adult cardiology.

Color↗
PubMed1987

[Ultrasonic diagnosis of aortic valve lesions in adults].

Based on a review of the literature and on a personal series of 136 cases the reliability of echocardiography and Doppler echocardiography in demonstrating aortic stenosis and regurgitation and its value for the analysis of aortic valve prosthesis is investigated.

Adolescent↗
PubMed1984

[Echocardiographic and electrocardiographic evaluation of the effects of propranolol and verapamil in obstructive hypertrophic cardiomyopathy].

The purpose of this study is to compare M-mode echocardiographic and electrocardiographic modifications obtained by short-term therapy (6 weeks) with high doses (480 mg/day) of propranolol or verapamil in six patients with hypertrophic obstructive cardiomyopathy. Propranolol prevents heart rate acceleration and reduces significantly the echocardiographic obstruction index during provocative testing with isoprenaline, when verapamil doesn't. However verapamil seems to be more able than propranolol to suppress ventricular arrhythmias as demonstrated in Holter monitoring. Evaluation of each patient suffering from hypertrophic obstructive cardiomyopathy with echocardiography and 24-hours electrocardiography would permit to better define appropriate therapy.

Adult↗
PubMed1983

[One- or two-dimensional echocardiography. A comparative study].

A consecutive series of 300 M-mode and two-dimensional echocardiograms was reviewed retrospectively by 2 independent observers. These tests had been performed in adult patients who were either ambulatory or hospitalized in a community hospital. The diagnostic contribution of two-dimensional echo in comparison to M-mode was nil in three-quarters of the cases; it was rated as important or essential in only 20% of the cases. It is concluded that M-mode echocardiography in adults retains its value in everyday cardiac practice.

Adult↗
PubMed1980

[M-mode and two-dimensional echocardiography in evaluating mitral stenosis before and after commissurotomy].

A first group of 51 patients with pure or predominant mitral stenosis underwent M-mode (M) and two-dimensional (2D) echocardiography and cardiac catheterization (cath). After elimination of 3 incomplete cases, the series consists of 48 patients. 20 later underwent surgery. Quantitative correlations between M and cath are poor (r = 0.34, p less than 0.05); however, correlations between 2D and cath were excellent (r = 0.89, p less than 0.001). There were 4 major discrepancies between 2D and cath: 3 of these patients were operated upon and surgery confirmed 2D mitral valve area in all of them. 2D had served to diagnose all 6 cases of mitral calcifications seen at surgery; however, M provided 1 false negative and 5 false positive results with regard to diagnosis of calcifications. A second group consisted of 18 patients who had undergone mitral commissurotomy, 8 of these had a pre- and postoperative echocardiography. 10 also underwent postoperative cath. M appeared to be unable to predict correctly the presence or absence of a recurrence of mitral stenosis. Quantitative correlations between diastolic slope and mitral valve area at cath were poor. However, excellent correlations were found between 2D and cath, showing that 2D also serves to measure mitral valve area after commissurotomy.

Calcinosis↗
PubMed1980

[Atrial septum defect: comparison of pre-and postsurgery echocardiographic data in adults and children].

Echocardiographic data in 13 adults and 17 children before and after surgical closure of an atrial septum defect are compared. Before surgery the enddiastolic dimension of the right ventricle was bigger in children than in adults. Septal motion was paradoxal or abnormal in 92% of adults and 65% of children (NS). Two weeks after surgery the right ventricle had decreased similarly in adults and in children, but often remained dilated. Septal motion was normal in 25% of adults and 76% of children (p less than 0.01). Four months after surgery, the right ventricle dimension was unchanged; septal motion was normal in all children but only in 50% of adults (p less than 0.005). This remaining abnormal septal motion after surgery may be explicable by the long-standing presence before surgery of a major shunt inducing chronic disturbances of right ventricular compliance.

Adolescent↗
PubMed1980

[M-mode and two dimensional echocardiography for evaluation of mitral stenosis (author's transl)].

M-mode and two-dimensional echocardiography (echo) were performed in 51 patients with pure or predominant mitral stenosis. Echocardiographic assessment of the severity of the stenosis was compared to the results of cardiac catheterization (cath); surgical evaluation of the mitral valve area was also obtained in 20 patients. M-mode is an excellent method for the diagnosis of mitral stenosis. However two-dimensional echo is much better for the assessment of its severity; in the present study correlations with cardiac catheterization have been excellent (r = 0.89, p less than 0.001). Major disagreement between echo and cath were found in 4 patients; 3 of them have been operated on and surgery has confirmed the echo results in all 3. Two-dimensional echo has also allowed correct prediction in the presence of mitral calcifications in 6 of the operated patients, whereas several false positive and negative diagnosis was made on M-mode. Two-dimensional echocardiography is therefore an excellent non-invasive technique for the diagnosis of mitral stenosis, measurement of mitral valve area and identification of mitral calcifications.

Adult↗
PubMed1979

[Bidimensional echocardiography in evalulation of mitral and aortic stenosis].

The aim of this study was to compare the results of unidimensional and cross-sectional echocardiography and cardiac catheterisation in the assessment of mitral and aortic stenosis. 21 patients with mitral stenosis, 21 patients with aortic stenosis and 21 patients without valvular disease were studied by unidimensional and cross-sectional echocardiography and cardiac catheterisation. Although unidimensional echocardiography in the external cardiac investigation of choice for the qualitative diagnosis of mitral stenosis, a better assessment of the severity of the stenosis is obtained with cross-sectional echocardiography. The valve surface measured by cross-sectional echocardiography correlates well with the value obtained by catheterisation with the application of the Gorlin formula (r = 0.85). Cross-sectional echocardiography is therefore an important advance in the external assessment of mitral stenosis. The aortic valve can only be measured in one third of cases of aortic stenosis with unidimensional echocardiography, whilst this measurement can be performed in 90 p. 100 of cases with cross-sectional echocardiography. The values obtained in 9 patients with severe aortic stenosis were 3.7 +/- 0.7 mm/m2, in 7 patients with moderate aortic stenosis: 5.4 +/- 0.8 mm/m2 and in 5 patients with mild aortic stenosis: 6.8 +/- 1,2 mm/m2. There is a clear demarcation between the different groups if the average values are compared. Therefore cross-sectional echocardiography gives reliable semi-quantitative assessment of the severity of aortic stenosis.

Adult↗
PubMed1977

[Usefulness of echocardiography in the diagnosis of bacterial endocarditis].

Echocardiographic demonstration of vegetations has been achieved in 11 out of 19 patients with bacterial endocarditis. The present study shows that echocardiography is particularly useful in patients in whom the duration of symptoms before treatment is greater than 6 weeks. It also shows that a positive echocardiogram is indicative of a poor prognosis.

Echocardiography↗