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Biomedical subjects

C McConnell

Publications and source records attributed to C McConnell.

13 recordsLinked to original sources

Renal artery embolization for benign obstructive uropathy.

PURPOSE: We demonstrate safety of renal artery embolization as an alternative to nephrectomy in symptomatic patients with obstructed, poorly functioning kidneys who are unfit for surgery. MATERIALS AND METHODS: We performed renal artery embolization in 2 medically unfit patients with benign obstructive uropathy and poorly functioning kidneys. The affected kidney was initially drained with a nephrostomy tube and the kidney was then selectively embolized using absorbable gelatin sponge particles and Gianturco coils. The nephrostomy tube was removed before hospital discharge. RESULTS: Urine production by the affected kidney ceased and symptoms resolved. CONCLUSIONS: Renal artery embolization with antegrade drainage is a safe alternative to surgery in unfit symptomatic patients with benign obstructive uropathy and poorly functioning kidneys.

Aged↗

Brief, intermittent hypoxia restricts fetal growth in Sprague-Dawley rats.

This study was conducted to determine whether brief, intermittent exposure to hypoxia with little change in nutrient intake would affect fetal growth. Pregnant rats were exposed to 1 or 2 h of hypoxia (FiO2 = 0.09-0.095) from days 15 to 19 of gestation. Exposure to 1 h of hypoxia decreased fetal body weight and length, liver weight and increased the brain/liver weight ratio (p < 0.05) as compared to controls. Two hours of hypoxia decreased fetal body weight and length, and heart, lung, kidney, gut, brain and liver weights (p < 0.01), but did not affect the brain/liver weight ratio. Two hours of hypoxia decreased maternal food intake and weight gain (p < 0.05), but fetal growth was not significantly altered in pair-fed controls. These data demonstrate that brief, intermittent periods of intrauterine hypoxia have significant effects on fetal growth.

Animals↗

Promoting informed decision-making about tattooing for adolescents.

In the February issue, the authors identified tattooing as an adolescent at-risk behavior, summarizing adverse purchase and possession factors as well as potential health threats of blood-borne disease. This information stems from a study of adolescents in five suburban high schools and one large urban school district in Texas. Promoting self-identity seems to be the key motivation for the tattooing. Investigating specific risk-taking behaviors of adolescents is important in order to create applicable health-promotion strategies. This article summarizes the development of a health education brochure, which was created on the basis of a review of the literature, an analysis of data, and field testing of the product. The purpose of the health information is to emphasize potential risks, pose definite questions and actions to minimize the risks, and encourage reconsideration or postponement of tattoo decisions.

Adolescent↗

Tattooing in adolescents: more common than you think--the phenomenon and risks.

Adolescents are obtaining tattoos, yet professionals in medical and sociological fields attribute it mostly to gang affiliation. Further information about this at-risk behavior is needed so school nurses can plan and implement applicable health promotion strategies. A total of 642 adolescents from five suburban high schools and one large urban school district in Texas participated in this study. Tattooed adolescents (N = 105) described their decisions, events, and experiences before, during, and after the tattoo procedure so purchase, possession, and health-risk factors could be examined. Over one-third of the non-tattooed adolescents are considering tattooing in the future.

Adolescent↗