PubMed Health⌕ Search

Biomedical subjects

C Meşină

Publications and source records attributed to C Meşină.

12 recordsLinked to original sources

Ectopic osteogenesis in the rectus sheath.

Although was published many cases of ectopic osteogenesis of traumatic, neurogenic cause or hereditable form, the etiology of ectopic osteogenesis remaining unknown. We present ectopic osteogenesis in the rectus abdominal sheath. The study material was represented from fragments of ectopic bones discovered in rectus sheath of four patients suffering iterative surgical abdominal interventions. The pieces of ectopic bone were decalcified and then were made to the standard techniques (paraffin inclusion, general techniques dyeing). The process of ectopic osteogenesis was analyzed through microscopically study to seriated sections of discovered piece, finding the presence of the hematopoesis foci. We conclude that is important identifying and characterizing the osteoinductor agents because these allowed the study of osteogenesis to the cellular level and make an estimation of the abnormally bone developing mechanisms. A possible osteoinductor factor has been considerate the non-absorbable wound closure material.

Aged↗

[Abdominal tuberculosis: clinical and therapeutic evaluation].

In this paper we present our experience concerning abdominal tuberculosis. The aim of this study is to evaluate various methods and to establish therapeutic approach to patients with abdominal tuberculosis. There were six patients (3 males and 3 females), aged between 22 and 67 years old, such as: 2 patients developed peritoneal tuberculosis, 3 patients developed intestinal tuberculosis and one patient developed mesenteric lymph node tuberculosis. We concluded that early diagnosis is often impossible and laboratory report was non-specific. Because surgical treatment in abdominal tuberculosis was made in complicate forms, we concluded that enterostomy "a minima" is the best therapeutic method.

Abdomen↗

[Upper digestive tract bleeding from ulcer with unusual etiology].

Case report of 40 year old female, admitted in emergency because signs and symptoms of upper digestive tract bleeding. Reappearance of bleeding, during haemodynamic compensation and dramatic installation of a haemorrhagic shock determines the surgical intervention for haemostasis. During surgery we discovered a duodenal ulcer with hypertrophic vessels, penetrating the gallbladder, that in its clinical course eroded the cystic artery. We performed bipolar cholecystectomy; removed the duodenal ulcer with anterior pilorectomy, Burlui antro-duodenostomy with a favorable postoperative course.

Adult↗

[Coloesophagoplasty, a choice operation for postcaustic esophageal stenosis].

OBJECTIVE: To evaluate the problems of approach, of technique and of care as a 20 years experience demonstrates. MATERIAL AND METHOD: a retrospective study including 45 operated cases where the large-bowel served as reconstructive material (in 33 cases the transverse colon and in 12 cases right ileocolon). RESULTS: Healing was obtained in 42 patients. Early postoperative evolution presented: peritonitis caused by anastomotic leakages--2 cases, hemoperitoneum--2 cases, cervical fistula --1 case, wound infection--6 cases, evisceration--1 case, acute respiratory failure--6 cases. Cervical anastomosis reconstruction for late stenosis--1 case. There were 2 postoperative deaths by haemorrhagic shock and peritonitis--mortality 4.4. DISCUSSIONS: Reconstruction by using the large-bowel was justified through anatomic argumentation (sufficient vascular supply), technic argumentation (easy anastomosis, tension free, short time of execution), functional argumentation (good compliance of large-bowel to the new function). CONCLUSION: Coloesophagoplasty is an efficient method on the condition of a strict planning: continent gastrostomy and evolvement of vascular arcades due to previous vascular "carving".

Adolescent↗

[Primary retroperitoneal tumors--diagnostic and therapeutic difficulties].

This paper emphasizes the diagnosis and therapeutic difficulties in primary retroperitoneal tumors. There were analyzed 68 primary retroperitoneal tumors (1992-2002): 16 (23.5%) benign tumors, 39 (57.35%) malignant tumors and 13 tumors with unknown histological structure. The preoperative diagnosis was clinically suggested and confirmed by ultrasound and CT examination; the operability was always established by laparotomy. All cases were operated on: complete resection of tumor was possible in 39 cases (57.35%); partial resection in 11 cases (16.17%) and 18 (26.47%) cases were inoperable. There were 5 major intraoperative vascular lesions: 1 inferior vena cava lesion, 1 superior mesenteric vein lesion, 1 left common iliac vein lesion and 2 lumbar artery lesions. Postoperative mortality was represented by 2 cases. Postoperative complication was represented by 3 postoperative hemorrhages, 2 severe pulmonary infections, 1 postoperative evisceration, 1 postoperative acute pancreatitis and 1 acute myocardial infarction. In conclusion the primary retroperitoneal tumors represent a challenge for all surgeons, especially due to surgical approach difficulties, because of problems in tumors intraoperative exploration and resection and because of difficulties in hemostasis.

Adolescent↗

[Unusual late complication after esophagoplasty type Gavriliu II for esophageal stenosis from chemical burns--cancer of the esophagoplasty tube].

We present the case of a 56 year old female, who in 23 years after esophagoplasty type Gavriliu II, with pre-sternal tube for esophageal chemical burn stenosis, develops a cancer in the upper third of the gastric tube, with a fast evolution to malnutrition, through lumen obturation. The evolution post-esophagoplasty was marked by malfunction of the neo-esophagus, characterized through dysphagia and distal dilatation, requiring many abdominal and pre-sternal reinterventions. The objective of the present surgical intervention was to assure a way for enteral nutrition (gastrostomy for feeding) and to extirpate the gastro-esophagoplasty tube. It is discussed the characteristic feature of the case: the difficulty of the stage-evolutive integration of this malignant disease location, the etiopathogenic factors that contributed to the malignant evolution of the antral portion of the gastro-esophagoplasty tube, the limits of the surgical treatment.

Adenocarcinoma↗

[Severe nosocomial infection of soft tissue in general surgery].

This paper aim is to emphasize the severity of soft tissue nosocomial infections, determined by anaerobic bacteria associated with Gram-negative aerobic bacteria: 50% mortality, higher economic costs, disabling morphologic and functional sequels. We present the pathogenic, clinical and therapeutically problems which characterize this type of postoperative infections.

Aged↗

[Gastrointestinal stromal tumor (GIST) with jejunum localisation, unusual source of digestive bleeding. Considerations about two cases].

Gastrointestinal stromal tumors are those gastrointestinal tumors , which expression antigens for CD 117 and CD 34. GIST arise from c - kit gene mutation through inadequate function of KIT enzyme (thyroxine kinase). However, the name is gastrointestinal stromal tumor, their localisation maybe under esophagus, stomach, duodenum, small bowel or colorectal.. CT scanning shows tumoral mass with nonspecific affiliation thanks to this development extraluminal and exophytic. Digestive hemorrhage, through GIST with small bowel localisation was called "obscure" because of impossibility to detect preoperative a bleeding source. We present, two cases of hemorrhage through GIST with jejunal localisation, male 70 years old with 10 cm tumor, discovered through CT scanning such as tumoral mass in left hypochondrium and female 55 years old, with 3 m tumor, discovered through emergency laparotomy for severe digestive bleeding. Also, it is discussed the possibility of intraoperative diagnosis, criterion to appreciate benign and malign features of the tumors and to determine their mitotic index for the supervision of these two cases.

Aged↗

[Crohn's disease. Clinical and therapeutical considerations].

Crohn's disease is a chronic granulomatous inflammatory condition of the intestinal tract of unknown etiology. Most commonly the disease affects the small bowel, the colon and the rectum. The acute and aggressive forms can evolve fast, mimicking an acute surgical illness, requiring surgical intervention in emergency. Surgical therapeutical option, in this condition, must be determined strictly by establishing a correct intraoperative diagnosis, through macroscopic features and histologic evidence. Because it is an incurable disease with variable evolution, marked by recurrence, that involves repeated surgical intervention, the surgical treatment (often resection), must be most conservative from the small bowel. We present 3 cases of surgical interventions with emergency characteristics (bowel obstruction through fitobezoar, colonic tumors obstruction of colon splenic angle, urachal infected tumors). In these cases the diagnosis was established intraoperatively and the surgical intervention was adapted to the particular cases.

Adult↗

[Hemorrhagic intestinal lymphangioma --report of a case].

This paper presents the case of a male patient, 57 years old, admitted to the hospital for upper digestive bleeding revealed by melena stools. The upper digestive endoscopy has not discovered the source of bleeding. Conventional medical therapy, with hemostatics, proton pump blockers and transfusion, failed to stop the bleeding, requiring emergency surgery for stopping the bleeding. The intraoperative exploration discovered three submucosal formations with dimensions between 0,5 and 0,75 cm, who ulcerated the jejunal mucosa, situated at 20-25cm from the duodeno-jejunal angle. The pathologic report described haemorrhagic intestinal lymphangioma. The excision of the sub-mucosal haemangioma stopped the bleeding.

Duodenal Neoplasms↗

[Sentinel nodes in patients with breast cancer].

The aim of this paper is to debate, on the basis of medical literature review, the importance of detection the sentinel nodes in surgery of breast cancer. The beginning of the paper emphasized the problems of the sentinel nodes definition, and then we discuss the dates related to the history and the importance of the sentinel nodes knowledge that consist in the avoidance of axillary lymph nodes dissection in patients with breast cancer N-. Afterwards, we present the indications for detecting the sentinel nodes and the criterion to exclude from the detection of the sentinel nodes. As a part of the results of surgery sentinel nodes, we present dates about the techniques of detection the sentinel nodes, the place of injection of the radiopharmaceuticals, the size of the radiocolloid. Finally, we come up in the conclusion that the identification of the sentinel nodes is useful and possible for majority of the patients with breast cancer T1 or T2N0M0.

Axilla↗