Biomedical subjects

C Meeuwis

Publications and source records attributed to C Meeuwis.

3 recordsLinked to original sources

PubMed2007

Targeting difficult accessible breast lesions: MRI-guided needle localization using a freehand technique in a 3.0 T closed bore magnet.

PURPOSE: To report the accuracy of magnetic resonance imaging (MRI)-guided needle localization for diagnosis of MRI detected suspicious breast lesions located in difficult accessible regions of the breast, using the freehand method in a 3.0 T closed bore magnet. MATERIALS AND METHODS: In five patients with five MRI-only breast lesions underwent MRI-guided needle localization for histopathologic evaluation of the lesions. All interventional procedures were performed in a 3.0 T MRI system with the patient in prone position and by using a dedicated phased array breast coil. MRI-guided needle localizations were performed by using a freehand technique. In our study, the high-resolution scan allowed preprocedural localization of all lesions without use of contrast enhancement. In all cases contrast-enhanced MRI was performed after insertion of the wire to confirm the tip of the wire in direct contact with the enhancing lesion. RESULTS: Needle localizations were performed in five patients. Histopathologic evaluation of tissue after surgery excision biopsy revealed one lymph node, three invasive ductal carcinoma and one ductal carcinoma in situ. Lesion size varied from 6 to 30 mm. Mean duration time was 25 min. No complications occurred during the intervention method. In the patient with the benign lesion control MRI of the breast after 6 months confirmed lesion removal. CONCLUSIONS: MRI-guided needle localization by using a freehand technique in a 3.0 T closed bore magnet is a safe and accurate method for diagnosis of difficult accessible breast lesions only visible on MRI.

Biopsy, Needle↗

PubMed2006

[MRI-guided biopsy of suspicious abnormalities in the breast].

In a 55-year-old woman, an echographically occult breast tumour was only visible in one direction on mammography. MRI-guided needle localisation of the lesion followed by surgical excision biopsy were then carried out for diagnostic purposes. In a second woman, 61 years of age, mammographic needle localisation of a deep, echographically occult, lesion was unsuccessful. She then also underwent MRI-guided needle localisation followed by surgical excision biopsy. A third woman, also 61 years of age, with known carcinoma underwent an MRI staging study. This revealed a second, mammographically and echographically occult, lesion for which MRI-guided large-core needle biopsy was done. MRI of the breast has a high sensitivity for the detection of invasive breast carcinoma. MRI of the breast reveals suspicious lesions that cannot be seen on the conventional mammogram or by echography in 15-25% of the cases. In order to obtain tissue from these lesions for histopathology, MRI-guided biopsy techniques have been developed. The most commonly used methods are MRI-guided needle localisation followed by surgical excision biopsy and MRI-guided large-core needle biopsy. The demand for MRI-guided breast interventions is growing because of the increasing use of MRI of the breast in clinical practice.

Biopsy, Fine-Needle↗

PubMed1996

The Blom-Singer tracheostoma valve as a valuable addition in the rehabilitation of the laryngectomized patient.

Prosthesis-assisted tracheo-esophageal speech has proven its value in post-laryngectomy voice rehabilitation, although manual occlusion of the tracheostoma during speech is necessary. In contrast a tracheostoma valve enables hands-free speech. We have now had experience with 30 patients using the Blom-Singer tracheostoma valve for more than 6 months and have found that most patients prefer prosthesis-assisted speech with the tracheostoma valve. Measurement of several speech parameters with digital and valve occlusion of the tracheostoma did not show any significant differences between the two speaking conditions. Problems included maintenance of an airtight seal, outward forcing of the valve diaphragm during forced expiration and subjective increased airflow resistance.

Adult↗