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C Meléndez

Publications and source records attributed to C Meléndez.

8 recordsLinked to original sources
PubMed1983

Sex differences in secretion pattern of neonatal rat Harderian gland under various environmental lighting conditions.

1. Secretion pattern of Harderian gland of neonatal rats maintained under (a) diurnal lighting conditions; (b) continuous light or (c) continuous darkness was studied at light microscopy level. 2. All animals were placed in especially designed cages at 13:00 hr on day 1 and studied on day 7 at 13:00 and 23:00 hr, respectively. 3. Acini with intraluminal secretion were counted in glands from each animal and the results were separately grouped for male and female animals. 4. A diurnal rhythm in secretion pattern of rat Harderian gland in neonatal period was demonstrated. 5. A statistically significant difference was observed in the gland secretion pattern between males and females at both, 13:00 and 23:00 hr when the animals were kept under diurnal lighting conditions. 6. Under continuous light or continuous darkness, the diurnal rhythm in secretion pattern was lost and no significant differences were seen when data from males were compared to those from female neonates. 7. Results are discussed in terms of the possible function of Harderian gland as element of an extraretinal photoreceptor system involved in the regulation of pineal function in neonatal rats.

Animals↗
PubMedDate not supplied

[Congenital mitral stenosis. Experience in 1991-2001].

OBJECTIVE: To describe ten years of experience with congenital mitral stenosis. METHOD: All cases with congenital mitral stenosis from January 1991 to 2001 were analized. RESULTS: 16 patients with congenital mitral stenosis were found, mean age 3 +/- 3.08 years. TYPES OF OBSTRUCTIONS: Mitral commisures combined with tendinous cords fusion (45%), parachute mitral valve 37%, supravalvar mitral ring in one, fusion between papillary muscle and leaflets in one, and double mitral orifice in one. Hemodynamic (in mmHg) findings: wedge pressure 18.4 +/- 4, pulmonary artery systolic 61 +/- 21, diastolic 34 +/- 15, mean 47 +/- 18 mmHg, mean transvalvar gradient (MTG) 12.9 +/- 7.3, PRU 5.5 +/- 3.8. Four patients received medical treatment. Surgical results: Six patients underwent mitral repair, and four were subjected to mitral valve replacement (two with previous mitral repair). Global mortality was 2 (12.5%). Follow-up was 3.5 +/- 3 years. There was a significant difference when the initial MTG 22.6 +/- 11.5 mmHg before surgical repair was compared with the final MTG 4.75 +/- 1.5 (P < 0.05), also when initial MTG 12 +/- 2.3 before mitral valve replacement was compared with the final MTG 6 +/- 1.15 mmHg (P < 0.05). CONCLUSION: Most patients are candidates for mitral surgical repair, however at mid term one third will require mitral valve replacement.

Child↗
PubMedDate not supplied

[Evaluation of arterial hypertension program in a primary care center].

The rate of detection, confirmation, control and follow-up of hypertension in the Canteres Primary Care Center was evaluated two years after the beginning of the hypertension program from a sample of 1219 clinical records. It was found that 572 individuals (46.9%) had at least one blood pressure reading. Of these, 68.2% had values within the normal range, whereas 9.6% of females and 2.8% of males were known hypertensives. High BP levels were found in 69 (19.9%) females and in 34 (15%) males. Of these 103 individuals, the three BP readings were only completed in 34 (49.3%) females and 12 (35.3%) males, and only 26 and 3, respectively, were considered as new hypertensives. In 87% of hypertensives the follow-up was correct, and 59% had BP within normal limits. It is concluded that priority should be given to more deprived and higher risk groups (males of working age), a new evaluation being proposed at 5 years with the following standards; greater than 80% with BP readings (greater than 95% in individuals older than 30 years), with correct confirmation of the diagnosis in greater than 95% and greater than 80% of control and follow-up.

Adolescent↗