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Biomedical subjects

C Merino

Publications and source records attributed to C Merino.

32 records · Page 2Linked to original sources
PubMed1984

Resistance of Aeromonas hydrophila to beta-lactam antibiotics.

The activity of some beta-lactam antibiotics upon 20 strains of Aeromonas hydrophila and some properties of their beta-lactamases have been studied. High degree of resistance to benzylpenicillin and lower resistance to ampicillin and cephaloridine was observed. Clavulanic acid showed the highest activity. When clavulanic acid was assayed at subinhibitory concentrations in association with ampicillin. MICs of the latter decreased to two- to eight-fold. All strains produced inducible beta-lactamases with high activity upon ampicillin. A group of cephalosporinase-like enzymes was also found. Some beta-lactamases were inhibited by cloxacillin, and most of them were completely inhibited by 5 mg/l of clavulanic acid. Low impermeability of Aerom. hydrophila cells to beta-lactams was observed.

Aeromonas↗
PubMed1983

Differential susceptibility of Aeromonas hydrophila and Enterobacteriaceae to nalidixic acid.

The susceptibility of 49 strains of Aeromonas hydrophila and 77 strains of Enterobacteriaceae towards nalidixic acid was compared by tube dilution and agar diffusion methods. A higher susceptibility was exhibited by Aerom. hydrophila and no overlap in MICs was found for strains of the two groups of microorganisms. Discs containing 0.25 microgram of nalidixic acid produced measurable zones of growth inhibition with Aerom. hydrophila and no zones with the Enterobacteriaceae. The use of a disc with 0.25 microgram of nalidixic acid for the primary differentiation of strains of Aerom. hydrophila from those of the Enterobacteriaceae with similar biochemical properties is suggested.

Aeromonas↗
PubMed1981

[Infantile cortical hyperostosis and fatal varicella (author's transl)].

We report a male, prematurely born, affected by an Infantile Cortical Hyperostosis. He had very frequent infections in skin, ear, meninges, gastrointestinal and respiratory system. He died at 13 months during a varicella, and an immunological defect was suspected, but could not be proved. Our patient showed some remarkable peculiarities. He was premature, uncommon fact, and associated constant infections, undernutrition and fatal varicella. This case support the relationship between Infantile Cortical Hyperostosis and infection.

Bacterial Infections↗
PubMedDate not supplied

[Renal hydatid cyst: a nuclear magnetic resonance study].

A case of renal hydatid cyst (R.H.C.) in which study both traditional diagnostic methods (such as serology, radiology, ecoraphia, C.A.T., etc.) and the newer ones, including Nuclear Magnetic Resonance (N.M.R.) were used, is presented. The diagnostic characteristics of this type of cystic pathology were reviewed through N.M.R. study, as well as current criteria to outline a correct differential diagnosis with simple Renal Cysts (R.C.). Finally, a theoretical place for each of these methods within the diagnostic algorithm of renal masses is suggested.

Aged↗
PubMedDate not supplied

[Chemoprophylaxis of superficial tumors of the bladder with thiotepa: long-term results].

A retrospective study was done on the long-term evolution of 48 patients diagnosed of transitional cell carcinoma of the bladder who were treated with full transurethral resection and intracavitary chemoprophylaxis with Thiotepa. All patients presented a minimum disease control period of 36 months, and were followed for 85.3 months on the average (38-156) months. The actuarial study of the relapse-free intervals turned out into a possibility of 89.3% of patients without a relapse by 5 years, and of 64.6% by 10 years. The actuarial study of tumor progress showed that 91.4% and 58.8% of the patients were free of progression by 5 and 10 years respectively. pT1-G3 tumors did not show greater relapse rate nor progression than the rest of cases, it is therefore convenient to consider other prognostic factors in the long-term evolution of these patients. 85.7% of patient deaths were due to direct consequence of the bladder tumor. These results and their clinical implications are analyzed.

Administration, Intravesical↗
PubMedDate not supplied

[Pneumatic dilatation in patients with esophageal achalasia].

From October 1984 to March 1992, 21 patients of Hospital Nacional Guillermo Almenara Irigoyen-IPSS, Lima, Perú, with esophageal achalasia were treated with pneumatic dilatation using a 3.5 cm diameter Rider-Moeller balloon. The mean age was 40.5 years (range: 24-54). Six were men and 15 women. The mean time with dysphagia previous to treatment was 5.3 years. A total of 29 sessions were performed, 1.38 sessions per patient. The follow-up of the first 10 patients was carried for a mean time of 48.3 months (range:6-91). A satisfactory response to treatment was obtained in 8 patients (80%). Two patients (20%) relapsed after 2 and 3 treatment sessions needing surgery. One patient suffered a esophageal perforation recovering after surgical treatment. We conclude that pneumatic dilatation with Rider-Moeller balloon is a safe and not difficult medical procedure for esophagus achalasia.

Adult↗