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Biomedical subjects

C Merlet

Publications and source records attributed to C Merlet.

At least 19 recordsLinked to original sources
PubMed1983

[Treatment of gout].

Explore the source record for details and available documents.

Combined Modality Therapy↗
PubMed1983

[Physiology and main implications of magnesium in osteo-articular pathology].

The role of magnesium in the constitution, metabolism and hormonal control of bone tissue can be deducted from what is known of its physiology. Magnesium deficiency may result in vitamin-D resistant hypocalcaemia or even biochemical signs of hypoparathyroidism, which only regress after the deficiency is corrected. Measurements of magnesium levels in blood and urine are justified when such abnormalities occur in patients with digestive disorders, predominantly alcoholism, liver diseases or malabsorption. In all other circumstances, magnesium therapy is very rarely indicated for osteo-articular diseases.

Animals↗
PubMed1983

[Articular manifestations of Whipple's disease. A case of sacroiliitis and destructive coxopathy].

Whipple's disease is a systemic illness whose pathogenesis, which is still poorly understood, implies an infectious agent accessible to antibiotic therapy. The authors report a case which is made unusual by the manifold systemic manifestations, important eosinophilia and destructive nature of the joint lesions of the hips. The physiopathological mechanisms of ocular and cutaneous manifestations are considered. A dramatic improvement is obtained with tetracyclin.

Adult↗
PubMed1983

[Destructive non-tumoral osteoarthropathies of the shoulder].

Destructive arthropathy of the shoulder is reviewed and the indications of total prothesis are briefly considered. It seems that the long term functional tolerance of destructive arthropathy of the shoulder is better than would be expected considering the radiological damage which is often substantial. The indications of shoulder prosthesis are dominated by rheumatoid polyarthritis and are infrequent in the other forms of these arthropathies.

Arthropathy, Neurogenic↗
PubMed1983

[Plasma exchange in rheumatology. Technical problems, tolerance, indications].

Plasma exchange, used since 1979 in the treatment of severe rheumatoid arthritis, has been the subject of numerous publications in the recent years. According to data from a review of the literature and from our personal experience, this therapy cannot be advocated in the usual forms of rheumatoid arthritis. Because of the side-effects, the complicated technical equipment required and the short duration of therapeutic results, plasma exchange should, for the time being, be restricted to malignant forms of rheumatoid arthritis, polyvisceral exacerbations in lupus and scleroderma, and hyperviscosity syndromes in globulinopathies.

Arthritis, Rheumatoid↗
PubMed1983

[Cauda equina syndrome and ankylosing spondylitis. Association with acromegaly. A myelographic and tomodensitometric study of the lumbar canal].

Cauda equina syndrome is a rare neurological complication of ankylosing spondylitis. The specific myelographic and tomodensitometric anomalies are exemplified by the reported observation. This case is unusual by the moderation of the neurological manifestations, and especially by the absence of sphincteral disorders. The characteristic roentgenologic signs of ankylosing spondylitis are associated with a scalloped appearance of the lumbar spinal column and antecedent quiescent acromegaly.

Acromegaly↗
PubMed1982

[Treatment of severe or vasculitis associated forms of rheumatoid arthritis by plasma exchanges (author's transl)].

Five patients with typical seropositive rheumatoid arthritis were treated by plasma exchange. All patients had severe affections resistant to conventional treatment, while in four cases the disease involved extra-articular localizations: rheumatoid nodules (3 cases), polyneuritis (1 case), skin necrosis (1 case). Each patient received between 5 and 10 plasma exchanges over a period of 3 to 4 weeks. No major complications were observed. Immediate results were very good in all cases, as shown by absence of clinical expression of the arthritis, marked regression in extra-articular symptoms, and reduction in erythrocyte sedimentation rate without parallel alterations in rheumatoid factor levels. Improvement lasted for only a few weeks in 3 patients, in one case preceded by an acutely painful episode. In the remaining 2 cases, with associated vasculitis, improvement has been sustained for a period that now exceeds one year. Results are compared with those reported in the published literature, and the mode of action and indications for plasma exchange in rheumatoid arthritis discussed.

Adult↗