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Biomedical subjects

C Messmer

Publications and source records attributed to C Messmer.

5 recordsLinked to original sources
PubMed1991

Influence of betaxolol and timolol on the visual fields of patients with glaucoma.

In a double-masked study, 40 patients with primary open-angle glaucoma were randomly assigned to treatment with betaxolol 0.5% or timolol 0.5% in both eyes twice daily. Visual fields and intraocular pressures were studied. Perimetry was performed with the Octopus G1 program two weeks after a washout period and three, six, 12, and 18 months after initiation of treatment. Both drugs reduced intraocular pressure. The reduction in intraocular pressure in the timolol-treated group was more pronounced than that in the betaxolol-treated group; the difference, however, was not statistically significant. In both treatment groups, the visual fields tended to improve during the first six months of treatment and remained stable or tended to deteriorate thereafter. The treatment effect on the visual field was better in the betaxolol-treated group than it was in the timolol-treated group (P = .041).

Aged↗
PubMed1991

[Effect of betaxolol and timolol on visual fields in glaucoma patients].

In a prospective, randomized, double-masked study, primary open-angle glaucoma patients were treated twice daily with either betaxolol 0.5% or timolol 0.5%. Patients received a pretreatment baseline examination following a 2 week washout period; they were then examined after 3 and 6 months of treatment. Each examination included visual field measurements with an Octopus automated perimeter and intraocular pressure measurement. The visual fields of the betaxolol group showed on the average a pronounced tendency toward improvement (MD decrease of 2.05 dB); visual fields in the timolol group showed a slight tendency toward improvement (MD decrease of 1.56 dB). The difference between these 2 trends after 6 months was statistically not significant (p greater than or equal to 0.05, U-test). Both drugs lowered intraocular pressure, there was no significant difference between the two drugs (p greater than or equal to 0.05, U-test).

Betaxolol↗
PubMed1991

Octopus program G1X.

The glaucoma program G1 is widely employed by Octopus users. In addition to a specific distribution of test locations, its main advantages are the quick comparison of results with normal values and an easy follow-up. The program, however, is relatively time consuming and, therefore, tiring for some patients. For this reason, the program was modified to 'G1X'. This program is interruptable at any time and provides information, including statistical analysis based on the available data. The test sequence is rearranged in accordance with the importance of the information. The available information, including the confidence limits, is continuously calculated and presented on the screen of the Octopus 1-2-3 during the test procedure. This provides the possibility of adapting the measurement to the patients and their state of health. The principal features as well as clinical applications are described.

Glaucoma↗
PubMed1990

[The Opacity Lens Meter 701: clinical experiences].

The quantitative influence of cataracts on visual fields was studied in 11 patients before and after cataract extraction with intraocular lens implantation. Lens opacity, measured with the Opacity Lens Meter 701, correlated closely with the visual field changes. Measurement of stray light backscattered from the cataractous lens permits quantitative prediction of the influence of cataract on the visual field.

Aged↗