PubMed Health⌕ Search

Biomedical subjects

C Mieras

Publications and source records attributed to C Mieras.

At least 19 recordsLinked to original sources

[Scabies vs. histiocytosis X: a possible diagnostic error].

Scabies is a relatively common disease among Spanish children. The classic papulovesicular type is not usually a diagnostic problem. Therefore, the nodular type, much less frequent, is unknown for a lot of specialists (except dermatologist), and even it is mistaken for Histiocytosis or Lymphoma. Authors present a female infant, 6 months old, with nodular skin lesions whose first diagnosis was X-Histiocytosis. Regarding the big difference between the two processes (in respect of prognosis and treatment), this chance should be excluded, among others, when X-Histiocytosis is suspected in a child with sole skin affectation.

Biopsy↗

[Panniculitis in pancreatic diseases].

A case of panniculitis in a patient with a pancreatic pseudocyst is described. Etiologic possibilities of the dermic lesions are analized, pointing out the role of the antiproteolytic enzymes and immunologic factors. In our patient neither immunologic or alpha-1-antitrypsin anomalies were detected. The skin lesions are probably related to the release of the pancreatic enzymes into the blood.

Adult↗

[Epidermolysis bullosa letalis].

A case of epidermolysis bullosa letalis in a newborn is described by the authors. The girl had numerous lesions for all the tegument except on the face, palms and soles. Something of them were bullous. The histopathological examination revealed a bulla with detachement dermoepidermic. Without infiltrate in dermis. The roof of the bullae is conservate. In the PAS stain we show the detachement over of the basal membrane.

Epidermolysis Bullosa↗

Necropsy and ultrastructural findings in histiocytic medullary reticulosis.

In a case of histiocytic medullary reticulosis with protracted course and necrotic skin lesions, histological study revealed infiltration of the fat tissue by atypical reticulohistiocytic cells, areas of associated fat necrosis and vascular lesions. Autophagocytosis (phagocytosis of erythrocytes, erythroblasts, platelets, lymphoid cells, and nuclear debris) was found in biopsy specimens of the subcutaneous infiltrates, lymph nodes, and bone marrow, and in necropsy specimens of skin, iliac mesenteric lymph nodes, bone marrow, liver, spleen, and suprarenal glands. Electron microscopy of various viscera showed abnormal histiocytic cells containing multiple phagocytosed erythrocytes and other blood cells in different stages of destruction and digestion. Multi-membranous bodies also were present. Defective lysosomal degradation of intracytoplasmatic ceroids in this condition is postulated.

Adrenal Glands↗

[Pseudoxanthomatous mastocytosis with aspects of nervus elasticus].

A case of mastocytosis is presented by the authors. The lesions appeared in early childhood with the typical appearance of urticaria pigmentosa. With the course of the years they changed becoming micropapular and assuming the appearance of the clinical picture described by Griffiths and Daneshbod as pseudoxantomatosis mastocytosis, although some clinical and histological aspects resembled the morphology and structure of the "nevus elasticus".

Adult↗

[Ultrastructural and cytological study of atypical fibroxanthoma].

A case of atypical fibroxanthoma of the skin is related. Ulstrastructural findings include: fibroblast-like cells, histiocytic-like cells, xanthomatous cells, and multinucleated cells. Strikingly similar findings were found by Fu and cols. (1975) in four cases of malignant fibrous histiocytoma. The authors postulated that both tumours could represent different aspects of a single proliferating process.

Aged↗