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Biomedical subjects

C Migdal

Publications and source records attributed to C Migdal.

31 records · Page 2Linked to original sources

Control of chronic simple glaucoma with primary medical, surgical and laser treatment.

This prospective clinical study comparing laser trabeculoplasty, medical therapy and surgery as the primary therapy for 168 patients with untreated chronic simple glaucoma, showed that the surgical group resulted in the lowest mean intraocular pressures, and was most effective in controlling the diurnal swing of intraocular pressures. Laser trabeculoplasty resulted in a lesser degree of pressure reduction but these patients were more frequently subject to high pressure spikes. Medical therapy was the least effective in lowering pressure.

Clinical Trials as Topic↗

Primary therapy for chronic simple glaucoma the role of argon laser trabeculoplasty.

This report compares the preliminary findings in three groups of patients suffering from chronic simple glaucoma who were treated with either laser, medicine or surgery, as the primary therapeutic procedure, and followed for a minimum period of six months. It is suggested that there is a place for primary treatment by surgical trabeculectomy in those patients who present with advanced chronic simple glaucoma, while argon laser trabeculoplasty would appear to have a very definite role in the primary treatment of all other patients with this disease.

Aged↗

Bilateral primary choroidal melanoma.

A case of bilateral primary choroidal melanoma is described in a 51-year-old white male. Histological confirmation followed enucleation of the left eye and local excision in the right. A careful systemic evaluation failed to demonstrate any other primary or secondary melanomata. This case is the first bilateral primary choroidal melanoma reported in the United Kingdom and the first to be described in which histological confirmation was obtained as a result of local excision of one of the tumours.

Choroid↗

The developing bleb: effect of topical antiprostaglandins on the outcome of glaucoma fistulising surgery.

A prospective trial of topical antiprostaglandins versus placebo in the treatment of postoperative fistulising surgery followed up for 12 months is described. It is concluded that antiprostaglandins have little place in the management of these cases. A photographic record of evolution of the fistulising bleb is described, together with a scoring system devised for the evolution of the successful fistulising bleb. A comparison is made between appearance and function of the fistulising bleb based on the use of the water drinking test and tonography together with intraocular pressure as tests of bleb function. It is concluded that the appearance of the established bleb alone is an insufficient guide to function, particularly if further surgery--for example, cataract extraction--is required.

Adult↗

Effect of the method of enucleation on the prognosis of choroidal melanoma.

The prognosis following treatment of uveal melanomata depends not only on factors such as cell type and degree of mitotic activity, size and location of the tumour, and the age of the patient, but also on the method of enucleation, as surgical manipulation of the neoplasm may potentiate the shedding of malignant cells into the blood stream. One hundred and thirty-one patients treated by different methods of enucleation were reviewed and the mortality patterns assessed. The numbers of deaths over the first 5 years differed significantly between the different groups. A specific method of enucleation used for tumour-containing eyes is described and its importance emphasised.

Choroid Neoplasms↗

Bilateral retinoblastoma: the prognosis for vision.

In the treatment of retinoblastoma careful case selection is essential. Each eye is assessed individually; the worse affected eye is no longer routinely enucleated in bilateral cases. One hundred and sixteen patients were reviewed to assess the overall visual prognosis. 50% achieved a final acuity of 6/12 or better in one eye at the age of 8 years, and 2 patients had acuities of 6/12 or better in both eyes. Various methods of treatment are discussed.

Adolescent↗

Choroidal melanoma: the role of conservative therapy.

The indications for and the results of therapy with cobalt plaques and photocoagulation administered to patients with choroidal melanoma are reviewed in the light of present-day experience. 99 patients followed up for a minimum of five years are included in the study. The visual results and survival figures confirm that there is a definite place for these forms of conservative therapy of choroidal melanomata.

Adult↗

Sir Arthur Conan Doyle: the author was an ophthalmologist.

Sir Arthur Conan Doyle created the famous detective Sherlock Holmes, and his faithful companion, Dr. Watson. A graduate of the University of Edinburgh Medical School, Doyle (1859-1930) spent nearly ten years practicing medicine. During his years in general practice, Doyle gave particular attention to the eye. Later, he studied ophthalmology in Vienna and spent time with the best known ophthalmologist in Paris. He returned to London and established an ophthalmological office near Harley Street. His literary career soon overtook the medical career, but he made many references to medicine, and to ophthalmology in particular in his writings.

England↗

Congenital cataracts--management and visual results (Cape Town 1956-1976).

A survey of 123 patients with congenital cataracts treated at the Red Cross War Memorial Children's Hospital in Cape Town between 1956 and 1976. The various factors influencing the functional prognosis were examined and correlated with the final visual outcome. Practicalities, both pre- and postoperative, involved in the management of these cases are discussed. Parental motivation and cooperation throughout the period of treatment is emphasized.

Adolescent↗