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C Mihăileanu

Publications and source records attributed to C Mihăileanu.

11 recordsLinked to original sources
PubMedDate not supplied

[An analysis of the medical contraindications for poliomyelitis vaccination in a district of the city of Bucharest].

The authors report on the results of the analysis of frequency, motives and possible consequences associated to the medical contraindication of inoculations with TPDV (thermal polio-destroyed virus) during the antipoliomyelitis vaccination in the spring of 1989 in District 3 of Bucharest. The failure share in the first antipoliomylitis vaccination was of 2.2% in the 2,500 children selected: 46 (83.6%) were CIM in one of the inoculations and 9 (16.4%) in both inoculations with TPDV of the vaccination. Infectious acute affections were the most numerous motives (89.1-57.1%) of the medical contraindications of inoculation with TPDV; in 59.6-31.2% of these causes the hospitalization of the cases was necessary. The false contraindications were at the basis of 10.9-42.9% of the medical decisions that contraindicated inoculation with TPDV. Of the children with contraindications at inoculation with TPDV, 41.8% met the risk criteria after the first stage and 12.7% after the second stage of the vaccination.

Child, Preschool↗
PubMedDate not supplied

[An estimate of the index of collective measles immunity among the pupils in 8-year elementary education in 1988-1989 in sector III of the city of Bucharest].

The authors have verified morbidity antecedents in the medical files of 18.5% of the cohort of 47,354 students registered in classes I-VIII in the year 1988-1989 in the III-rd Sector of Bucharest. On the basis of simple hypotheses concerning the post-infectious anti-rubeola immunity, and the post-vaccinal immunity respectively an index was estimated of the anti-rubeola collective immunity of 89.1% a value associated to the risk of transmission of the rubeola infection in this cohort. These observations have permitted the authors to suggest anti-rubeola vaccination of students without documented evidence of anti-rubeola immunity on the one hand, immediately in all the classes (I--VIII) of the present scholar year, and, on the other hand, to vaccinate all the students in the first class, yearly, as an additional measure in the present control anti-epidemic strategy of rubeola.

Child↗
PubMedDate not supplied

[A plan for poliomyelitis vaccination].

A study of the vaccinal antecedents on a representative group of children between 12 and 45 months in the district 3 of Bucharest showed that there exists a certain and direct correlation between the number of simultaneous DTP/VPOT administrations programmed in the immunization scheme and the vaccinal coverage with I DTP revaccination at the minimum age recommended. Administration of VPOT at the ages of 3, 5 and 11 months, simultaneously with the corresponding doses of DTP is the most efficient immunization scheme with these vaccines, in order to proceed to steady rate of antipoliomyelitis vaccination.

Child, Preschool↗
PubMedDate not supplied

[An economic evaluation of measles vaccination in District 3 of the city of Bucharest].

The cost-profit analysis (CPA) of the anti-measles (AM) vaccination, 10 years after its introduction in the anti-epidemic strategy, shows that in the district 3 of Bucharest, the prevention, by vaccination, of more than 17,000 cases of getting ill was associated with a net profit of 11 X 10(6) lei, and a profit/cost ratio (PCr) of 6/1. These figures evidence the economic value of the AM vaccination and stimulate the further development of the programme for the control of measles by vaccination.

Cost-Benefit Analysis↗
PubMedDate not supplied

[Vaccinal coverage at 1 year of age of the generation of children born in February 1987 in District 3 of the city of Bucharest].

The authors checked the vaccine coverage and the situations in which the compulsory vaccines were not administered up to the age of one year in the children born in February 1987 in District III of Bucharest. The results show a vaccine coverage of more than 90% in BCG vaccination (99.4%), antipoliomyelitic with one dose (94.2%) and with two doses of oral polyvaccine (92.2%) respectively, and the first DTP vaccination (95.9%). The values were under 90% in antimeasles vaccination (87.2%) and the second vaccination with 1 DTP (25.5%). The main causes leading to vaccine coverage could have been prevented. Discussion of these results shows that better vaccination values might be obtained by improving the present control on the immunoprophylaxis activity of the paediatric medical units, by intensifying both their control actions and aims.

Humans↗
PubMedDate not supplied

[The risks of transmitting viral hepatitis in a section of the city of Bucharest].

The authors of the present paper consider that 82.3% of all cases of viral hepatitis in a Bucharest district were transmitted nonparenterally and only 17.7% were transmitted parenterally. They used the information on the way and mode of transmission, recorded in the epidemiologic investigations, of the cases of viral hepatitis without HBsAg in 1987 and of those with HBsAg in 1983-1987, respectively. The highest values of the risk of catching the disease were calculated for the infective social contact in family, in the viral hepatitis with HBsAg (60.9%), and for the infective social contact in collectivities (46.4%) in the viral hepatitis without HBsAg. These data have to be checked up by prospective epidemiologic studies, randomized and controlled.

Hepatitis B↗