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Biomedical subjects

C Milewski

Publications and source records attributed to C Milewski.

29 records · Page 2Linked to original sources
PubMed1992

[Esthetic aspects of excision of basaliomas of the area of the head and neck].

Eighty-four patients with basal cell carcinoma of the head and neck were submitted to surgery. In 75%, infiltration of the reticular dermis or the subcutis was documented. Primary closure of the wound was achieved in only one-third of these patients. In the remaining cases, the defects were closed by local flaps, regional flaps or a microvascular forearm flap. In 86% of the cases, good-to-excellent results were achieved.

Adult↗
PubMed1991

[Merkel cell carcinoma: an endocrine differentiated tumor in the head-neck area].

Merkel's cell carcinomas are rare tumours of the skin, frequently on the head and neck. Electron microscopical and immunohistological techniques are employed for differentiation from other skin malignancies. With two cases the clinical picture, the typical histology and the therapy are elucidated. To detect pathognomic antigen expression, antibodies against Neuron-specific-enolase (NSE) as a marker for endocrine activity and cytokeratin to prove the epithelial character of cells were used (Abb. 4 a,b). The best treatment of Merkel's cell carcinoma is surgical resection, including the regional lymph nodes. Consecutive radiotherapy is strongly recommended.

Aged↗
PubMed1991

[Results of tympanoplasty following application of cartilage-perichondrium transplants for tympanic membrane substitution under unfavorable circumstances].

From a series of 2335 cases of ear surgery over a five-year period, the author reports on 550 cases where perichondrium cartilage from the tragus or concha was used as transplant material. Two different surgical techniques were employed. The postoperative gain in hearing and the overall incorporation rate are presented.

Ear Cartilage↗
PubMed1991

[Artificial nutrition with nasogastric catheters. Experiences with a new administration system].

Enteral nutrition via a nasogastric tube is widely used but is inconvenient for patients: the nostril and skin of the nose become irritated and ulcerated, and the tube causes pain and psychological trauma. We have developed a new system which combines the security and ease of nasogastric tube feeding with comfort for the patient. The distal part of the tube is invisibly anchored in the vestibule of the nose, using a special device. The outer part is attached only when feeding is necessary. We report 52 ENT patients who have used this system.

Adult↗
PubMed1991

[Treatment of fractures of the orbital floor].

Extensive fractures of the orbital floor are often combined with other fractures of the facial skeleton, and require surgical treatment and reconstruction. In some cases the reconstructed orbital floor needs temporary support from the maxillary sinus to facilitate healing in the correct position. Over a period of 18 months a new low-pressure balloon, made from silicon with a tetrahedron shape, was used in 24 of 47 patients with lateral midface fractures. The post-operative results are presented and the treatment regimen is discussed.

Bone Plates↗
PubMed1990

[Bilateral congenital profound hearing loss and hypospadias--a new syndrome?].

Five children with hypospadia and profound hearing loss were presented to the Clinic for Speech and Communication Disorders of the University of Mainz. Anamnestic and laboratory investigations strongly suggest, that the malformations are interrelated and may represent a new syndrome. Therefore it appears to be helpful to carry out a routine hearing check in children, who are hospitalized for the first surgical treatment of hypospadias.

Audiometry, Pure-Tone↗
PubMed1988

[The risk of endocrine activation in interventional procedures on paraganglioma of the head and neck].

In the literature on paragangliomas or glomus tumors of the head and neck, the question rarely arises as to whether in endocrine inactive paragangliomas the tumor necrosis resulting from the embolization can release the stored substances. Based on 34 paragangliomas after surgical treatment, the angiographic and immunohistological characteristics of the paraganglionic, angiomatous and adenomatous tumors are presented. No catecholamine secretion occurred as a result of interventional or surgical treatment.

Antibodies, Neoplasm↗
PubMed1988

[Immunohistologic findings in paragangliomas in the area of the head and neck].

30 patients with paraganglioma of the head and neck region were subjected to surgery at the Department of Otorhinolaryngology during 1978-1985. Histological classification of the obtained specimens was performed using also immunocytochemical methods to detect more details. The site of origin of the tumours was the glomus tympanicum in 18 cases, 7 times the glomus caroticum and 5 times the glomus jugulare. Antibodies against neuronal components (S-100 protein), endothelial cells (UEAI) and endocrine activity (NSE) were used for subtyping by PAP-method (Figs. 1-3). Immunocytochemistry provided for an easy subtyping of the tumours and showed an increase in severe progress forms in adenomatous variants of paragangliomas.

Adult↗
PubMed1983

Clinical and morphological aspects of nephrotic syndrome in perimembranous, focally sclerosing and membrano-proliferative glomerulonephritis.

The following data was obtained by morphometric and photometric microscopic studies of renal biopsies from 140 patients with idiopathic perimembranous glomerulonephritis, 108 patients with focally sclerosing glomerulonephritis and 50 patients with membranoproliferative glomerulonephritis and correlation of the results obtained with available clinical data: 1. In all three diseases proteinuria and serum protein concentration show no tendency to stabilization in spite of increasing renal insufficiency. 2. With increasing renal insufficiency the proximal tubular cells become increasingly atrophic. 3. Protein resorption through the proximal tubulus cells becomes increasingly diminished with advancing renal insufficiency. It is concluded from the present data that proteinuria, which is primarily glomerular caused, is increased by increasingly diminished resorption of proteins in the tubulus system with increasing renal insufficiency. In this way, even under conditions of advanced renal insufficiency with reduced GFR, large amounts of proteins can be excreted and a nephrotic syndrome can persist to a stage of renal insufficiency.

Absorption↗