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Biomedical subjects

C Miranda

Publications and source records attributed to C Miranda.

At least 91 records · Page 5Linked to original sources

[Post-traumatic hemoperitoneum: a rare complication of peritoneal splenosis].

Peritoneal splenosis is a frequent condition after traumatic spleen fracture, which, given that it is usually asymptomatic, is often not diagnosed unless a laparotomy is performed for some other reason. The case is presented of a 9 year old boy splenectomized a few years earlier because of traumatism, who again suffers abdominal injury with the development of hemoperitoneum, observing during surgery multiple splenosis foci disseminated all over the abdominal cavity, some of which present rupture and hemorrhage, constituting the cause of hemoperitoneum.

Abdominal Injuries↗

[Insulinoma and pregnancy. Clinical case].

A 25 year old woman developed severe episodes of hypoglycemia during the first weeks of pregnancy. Insulin blood levels of 53 uU/ml and Peptide C levels of 6.5 ng/dl were shown associated to a blood glucose level of 34 mg/dl. Echotomographic examination of the abdomen was unrewarding. Surgical exploration revealed a 1.5 cm tumor located at the junction of the body and tail of the pancreas, which was removed. Hypoglycemia disappeared and pregnancy continued uneventfully ending in a normal delivery at 40 weeks. The newborn was normal and no motor or psychologic abnormalities have been noted during follow up to 2 years of age.

Adult↗

[Evaluation of the Vitek system in the identification and biotyping of Streptococcus agalactiae].

Using the Vitek card for identification of gram-positive agents, 244 strains of Streptococcus agalactiae were studied. Twenty five out of these strains were studied during 3 consecutive days. The study also involved 25 pairs of maternal and neonatal strains. The system gave correct identification of only 52 out of 244 strains of S. agalactiae. Due to the low reproducibility of the system it is suggested that the bionumbers used in the codification of a microorganism should be avoided.

Bacterial Typing Techniques↗

[Antimicrobial activity of ornidazole and 6 other antibiotics against anaerobic bacteria].

The antimicrobial susceptibility of 235 anaerobic bacterial strains to ornidazole, metronidazole, chloramphenicol, clindamycin, penicillin, cefoxitin and imipenem has been studied using agar-dilution technique. Ornidazole and metronidazole were active against 88.6% and 86% of gram-positive cocci. Overall, 99.1% of Bacteroides group fragilis, and 91.3% of non-fragilis Bacteroides were also sensitive to both drugs. We did not find any Clostridium perfringens resistant strain. Cefoxitin and penicillin showed good activity against all Clostridium perfringens strains, and also against 97.7% and 92.5% of gram-positive cocci. We found one single imipenem resistant strain among gram-positive bacteria. Bacteroides fragilis also showed sensitivity to penicillin (41.5%), cefoxitin (85.7%) and imipenem (97.1%). Clindamycin was active against Clostridium perfringens (90.9%), gram-positive cocci (86.7%) and imipenem (68.6%). Chloramphenicol showed good activity against Clostridium perfringens (100%), gram-positive cocci (95.5%) and Bacteroides spp. (99.4%). Our results showed an overall good activity of all the seven drugs tested against anaerobic gram-positive microorganisms. Of notice, we found a good activity of chloramphenicol, imipenem, metronidazole and ornidazole against Bacteroides spp.

Anti-Bacterial Agents↗

[Trophic effect of testosterone on erythropoiesis in the mouse].

Some differences between erythropoietin biogenesis under the action of natural stimuli and that resulting from testosterone administration are commented. Evidences are presented suggesting that androgens, apart from amplifying erythropoietin production, might exert some action on the stroma as specific erythrocytic tissue. This action could be anabolic or trophic and not erythropoietin dependent, at least to some extent, its effect being applied on the quantitative erythropoietic homeostasis.

Animals↗

[Echographic imaging of absence of follicular rupture. Endocrinologic aspects].

Since Jewelewicz in 1975 first described the luteinization of an unruptured follicle (LUF), clinical evidence for the importance of this syndrome has been given by various groups of investigators. Luteal phase of 14 cycles with ultrasound evidence of unruptured follicles were studied with plasmatic determination of levels of FSH, LH, prolactin, 17 B estradiol and progesterone each one day. Two groups were defined. One, with "ovulatory ranges" of progesterone, probably LUF syndrome and another, with "anovulatory levels", probably follicular cysts.

Estradiol↗

[Intramyoma intrauterine device].

This article describes a cases of "missing strings" of a Zipper IUD embeded in an intracavitary myoma. Two attempts with classical procedures failed to remove it and the diagnosis was done after a hysteroscopy complicated with uterine perforation. It is very difficult to assure if the myoma grew around the IUD or it was perforated at the time of its insertion. Histological evidences lead to the first option.

Adult↗

[Parasitic infections in renal transplantation patients].

We performed indirect hemagglutination tests for toxoplasmosis and Chagas disease, complement fixation test for toxoplasmosis, stool examination for parasites and Graham test for enteroparasites in 51 patients before and after renal transplant. Post transplant surveys were performed at 3, 6, 9, 12 and 18 months. 18 patients who were positive for toxoplasmosis remained so and 5 new asymptomatic cases were detected in the post transplant period (15%). Two patients who were positive for Chagas disease remained positive and asymptomatic. One patient receiving a kidney from a Chagas positive donor remains negative. Asymptomatic enteric infection was detected in 45% of patients at some time during follow up: amebic infection (25%), giardiasis (14%) and oxyuriasis (24%). Two patients showed asymptomatic cryptosporidiasis.

Chagas Disease↗

Echinococcal disease of the extrahepatic biliary tract.

Cystic hydatid disease of the liver is uncommon in the United States. It is caused by the larval cestode Echinococcus granulosus. One complication of this disorder is rupture of the hepatic hydatid cyst into the biliary ducts. There have been few reported cases of this complication of hydatid disease in the US literature. We describe a case of this disorder and briefly review the literature.

Adult↗

A simple method for concentrating erythropoietin activity in plasma and in other body fluids.

The method here described is based on the property of erythropoietin to remain in water solution in the presence of up to 60% ethanol. More than 90% of inert proteins precipitate in the process and can be eliminated without significant loss of the activity. The addition of sulfuric ether produces the separation of the water phase and of its solutes which can be recovered in the solid material obtained by lyophilization. Using this method a marked erythropoietin activity can be demonstrated in extracts of the plasma from mice with a moderate reduction of the hematocrit.

Erythropoietin↗