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Biomedical subjects

C Morera Pérez

Publications and source records attributed to C Morera Pérez.

15 recordsLinked to original sources

[Blood viscosity profile in rapidly progressive sensorineural hearing loss with positive Western-blot].

OBJECTIVE: To value a possible association between disorders in blood viscosity of patients with rapidly progressive sensorineural hearing loss (RPSHL) of autoimmune origin. PATIENTS AND METHODS: We studied the viscoelastic properties of blood in 43 subjects bearing of RPSHL and a positive Western-blot for anticochlear antibodies: whole blood viscosity (WBV) at different shear rates and erythrocyte filterability (EF). These results were related to hearing loss initially detected and recovery average one year later from steroid therapy. RESULTS: Just WBV at 230 sec(-1) shear rate was significatively higher in cases than in controls (p < 0.01). Hearing recovery degree correlated in an statistically way to increased values of EF (p < 0.01). There was no relation between initial hearing loss level and any rheology parameter. CONCLUSIONS: Autoimmune RPSHL does not show a pathophysiology mechanism associated to blood hyperviscosity. So, rheoactive therapies as plasmapheresis warrant no clinical improvement.

Adult↗

[Ménière's disease and migraine].

INTRODUCTION: The possible link between vertigo and migraine has been known for a long time as well as its association with Ménière's disease. OBJECTIVE: To determine the lifetime prevalence of migraine in EM patients and to compare it with the prevalence of migraine in general population according to the International Headache Society (IHS) criteria. METHODS: We interviewed 65 EM patients. Our results have been compared with a sex- and age-matched control group with no otological antecedent. RESULTS: The lifetime prevalence of migraine was significantly higher in Ménière group compared to the age- and sex-matched control group (35.4% versus 15.4%, p < or = 0.05). Nine patients with EM and migraine related an evident relationship between their vertigo episodes and the migraine. CONCLUSIONS: The results obtained in our study suggest the possibility of common pathophysiological mechanisms to both pathologies and it may lead to new therapeutic options for treatment of EM and migraine patients.

Adult↗

[Kinetic tests representativity in vestibular function].

INTRODUCTION: The most frecuently tests used to study the vestibular system, with videonystagmographic register, are the caloric and rotatory ones. MATERIAL AND METHODS: We have carried out a comparative study of the kinetic tests through a sample of 41 patients without vestibular pathology, stratified by age and gender. The performed rotational tests have been: Constant/cycles, postrrotatory test, increasing, decreasing and constant test. RESULTS: We have not observed age or gender influence on the results. We give the numeric results of these tests. CONCLUSION: The obtained data allow to conclude that the information given by the increasing and decreasing pendulous test is similar, phenomenon that doesn't happen in the rest of the practiced tests. We also study the habituation phenomenon to a know stimuli. We point out the importance of each laboratory to have their tests done previously in a normal control group in order to compare the results when performing them in pathological patients.

Adult↗

[Vestibular evoked myogenic potential: a contribution to the vestibular physiology and pathology knowledge. Quantitative patterns in healthy subjects].

INTRODUCTION: Vestibulocollic reflex is a muscular reflex which is activated by acoustic stimulation. It shows two components: the first one, the vestibular evoked myogenic potential (VMEP) related to the vestibular pathway and the second, to the auditive pathway. The VMEP potential could be useful for vestibular physiology and pathology knowledge. OBJECTIVE: To determine the VMEP's parameters of normality and to evaluate influential factors such as age, sex or stimulation intensity. MATERIAL AND METHODS: Prospective study of the VCR in 40 healthy individuals, distributed in 4 groups according to their age. Stimulation was carried out at 100db and 85db on each ear independently. RESULTS: There are not differences between both ears and sexes. Normal latency levels must be separated between two groups of age: older and younger than 11 years old. Normal absolute values of amplitude response differ depending on muscular contraction, age and stimulation intensity. It is more representative to consider the difference between the values obtained in the two ears of the same individual than to consider the absolute values.

Adolescent↗

[Primary tuberculous otitis media].

Tuberculous otitis media is now an infrequent disease, with an incidence of less than 1%. In most cases the origin is a pulmonary focus and primary cases are rarer. We report a case of primary tuberculous otitis media in an immunocompetent patient. A bibliographic review was made of clinical and etiopathogenic aspects, as well as diagnosis and treatment. We highlight the diagnostic difficulty and the fact that this entity should be included in the differential diagnosis of persistent suppurative otitis media.

Adult↗

[Meningoencephalocele: microsurgical endonasal approach. Report of two cases].

Neurosurgery is the commonest way of treating meningoencephaloceles, but there are cases with certain particularities allowing microsurgical approach through the nose, for instance nasoethmoidal sitting, small size,... We report our experience of 2 cases of meningoencephalocele removed through this approach, one of them reoperated because tumor recurrence.

Encephalocele↗

[Audiometric threshold shift in patients with cochlear implantation].

A great number of studies have been carried out during many years in order to evaluate the histological changes that take place after the insertion of a cochlear implant, having been experimentally and histologically, in temporal bones, demonstrated its relative harmlessness. We have focused our functional investigation induced by the implants through the shift of pre- and postoperative tonal audiometric thresholds, in 13 carriers on an C. I. Nucleus 22. Most of them suffered minimal or even showed no shift of thresholds. Therefore we consider the functional alterations due to the insertion of electrodes as practically nonexistent.

Adolescent↗

[Cochleovestibular nerve compression syndrome. A case report].

Cochleovestibular nerve compression syndrome is a term used to describe a group of audiovestibular symptoms produced by vascular compression of the cochleovestibular nerve. The most frequent abnormalities are sensorineural hearing loss, asymmetry of the wave I-III and III-V interval in the auditory brainstem response, and changes in electronystagmography. The clinical presentation varies and symptoms include recurrent vertigo, tinnitus, instability, and motion intolerance. A case is reported of cochleovestibular nerve compression syndrome in a 40-year-old woman with right ear hearing loss and occasional dizziness and tinnitus. Clinical exploration disclosed no relevant findings, but the auditory brainstem response showed an increase in the wave I-V interval. Contrasted magnetic resonance imaging identified a vascular loop near the cochleovestibular nerve. The differential diagnosis and treatment of this rare syndrome are discussed.

Adult↗

[Epidermoid of the petrous apex].

The AA. report a case of primary cholesteatoma of the petrous apex. These seldom cases show at the beginning trigeminal symptomatology. They are treated through a middle fossa approach. Survey of the literature.

Adult↗

[Results of an auditory screening program in preschool children].

Although important advances have been made in screening for neonatal hearing loss in recent years, there are no extensive studies of other age groups (2 and 3 years). In an audiological study of 284 children of this age using brainstem evoked potentials, we found some degree of deafness in 6.3%, 17% sensorineural and 70% moderate. The large percentage of hearing deficits found in this preschool population suggests that screening programs should be carried out.

Child, Preschool↗

[Hypertrophic osteoarthropathy in a patient with nasopharyngeal carcinoma].

A clinic-pathological study of a 12 year-old male diagnosed of non-differentiated nasopharyngeal carcinoma (NPC) was carried out. The patients presented secondary hypertrophic osteoarthropathy prior to the development of lung metastases. Hypertrophic osteoarthropathy is a clinic-radiological syndrome characterized by a neoformation of periosteal bone, fundamentally located in long bones and distal ends of metacarpal bones. Polyarticular and synovial involvement is also observed. Association between NPC and hypertrophic osteoarthropathy is uncommon and appears to suggest the existence of metastatic spread (probably to the lung), particularly in young patients.

Antineoplastic Combined Chemotherapy Protocols↗

[Pediatric laryngeal papillomatosis: our experience (three cases)].

Three cases of juvenile laryngeal papillomatosis were treated at our hospital between 1984 and 1994. Papillomas were excised in all patients because of upper airway obstruction. Two were given alpha interferon as complementary treatment. Two patients are asymptomatic after years of follow-up and one is still taking alpha interferon.

Antineoplastic Agents↗

[Emergency amygdalectomy and adenoidectomy in children with upper respiratory obstruction].

Hypertrophy of the adenoids and tonsils in children sometimes produces life-threatening upper airway obstruction that requires emergency endotracheal intubation followed by adenotonsillectomy. Four patients, age range 18 months to 3 years, who required emergency treatment in the Pediatric Intensive Care Unit were studied for acute respiratory distress syndrome with cyanosis and use of accessory respiratory muscles. Two had orotracheal intubation to stabilize their cardiorespiratory situation before surgery. One presented cardiomegaly and secondary pulmonary arterial hypertension. The third remained stable and adequately ventilated with naso-hypopharyngeal ventilation. The fourth remained in intensive care for its clinical situation, but did not require exceptional measures.

Adenoidectomy↗